The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2015Measuring Altered White Blood Cell Functionality as a Biomarker of Parkinson’s Disease
Study Rationale:
White blood cells from people with Parkinson’s disease (PD) patients appear to differ from those of control individuals in that there are differences in the set of genes that are... -
Research Grant Supplement, 2015The Influence of Bacterial Amyloid on Alpha-synuclein Misfolding in a Pre-clinical Model Supplement
Promising Outcomes of Original Grant:
We hypothesized that that deposits of the Parkinson’s disease-associated protein alpha-synuclein in gut and brain neurons are caused by exposure to proteins of... -
Research Grant Supplement, 2015Modulation of MicroRNA Activities in Parkinson's Disease
Objective/Rationale:
Previous data support that small non-coding gene regulatory RNAs, known as microRNAs, are dysregulated in Parkinson’s disease (PD). However, the disease-relevance of these changes... -
Improved Biomarkers and Clinical Outcome Measures, 2015Method to Quantify Parkinsonian Motor Signs for Interventional Drug Trials
Study Rationale:
Current methods to evaluate motor impairments in Parkinson’s disease rely on subjective examinations. Our team seeks to develop an objective assessment of motor... -
Research Grant, 2015Parallel Reaction Monitoring within the Parkin Ubiquitin Ligase System
Study Rationale:
Recent studies have revealed a role for PINK1 and PARKIN, two genes mutated in early onset Parkinson’s disease, function to promote a cellular process called ubiquitylation of... -
Improved Biomarkers and Clinical Outcome Measures, 2015Developing Progression Markers of Parkinson’s Disease with Multimodal Structural MRI of Substantia Nigra and Locus Coeruleus
Study Rationale:
Substantia nigra pars compacta (SNpc) and locus coeruleus (LC) are key brain areas involved in Parkinson’s disease. The loss of important chemicals (dopamine and norepinephrine) made...
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Our funding programs support basic, translational and clinical research from academia and industry.