The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarker Development, 2015Biomarker and DNA Samples Collection Add-on Study to the Phase III Trial of Isradipine
Study Rationale:
Isradipine, an FDA-approved agent for treatment of high blood pressure, was shown to be have neuroprotective benefit in models of Parkinson’s disease (PD). A recently completed Phase... -
Access to Data and Biospecimens, 2015Validation of a Blood-based Gene Expression Assay for Early Diagnosis and Monitoring Disease
Study Rationale:
The need for biomarkers in Parkinson’s disease (PD) is crucial for the early diagnosis of PD; monitoring PD severity/progression; and developing treatments that can... -
Research Grant, 2015Pre-clinical Development of the Oligomer Modulator anle138b and Establishment of a Novel Seeding-based Biomarker
Promising Outcomes of Original Grant:
In our previous work, we assessed the therapeutic potential of the oligomer modulator anle138b in pre-clinical models of Parkinson’s disease (PD). Anle138b... -
Target Validation, 2015Enhancing Mitochondria Quality Control in Parkinson’s via Activation of the Caseinolytic Peptidase
Study Rationale:
Reinforcement of mechanisms that maintain the health of the cell’s energy generator, its mitochondria, may combat age-related diseases including Parkinson’s disease... -
Target Validation, 2015Modulation of Microglia Cannabinoid Receptor 2 to Treat Neuroinflammation in Parkinson’s Disease
Study Rationale:
Numerous studies have highlighted a potential role of neuroinflammation in Parkinson’s disease whereby the immune cells of the brain called microglia may produce... -
Therapeutic Pipeline Program, 2015Effects of Transcranial Stimulation on Freezing of Gait in Parkinson's Disease
Study Rationale:
Many people with Parkinson's disease experience freezing of gait, when the person is unable to move forward, despite his or her best efforts. Although it is not exactly clear why or...
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Our funding programs support basic, translational and clinical research from academia and industry.