The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2014Restoring the Nigrostriatal Pathway with Living Micro-Tissue Engineered Axonal Tracts
Study Rationale:
By the time Parkinson’s disease (PD) symptoms appear, typically 60% of neurons in the substantia nigra and their axonal projections (nerve fibers) to the striatum... -
Rapid Response Innovation Awards, 2014Novel Mechanism for Death of Dopaminergic Neurons in a Model for Parkinson’s Disease
Study Rationale:
Parkinson’s disease (PD) is due in large part to the death of dopaminergic neurons in a part of the brain called the substantia nigra. An understanding of why, as we... -
Rapid Response Innovation Awards, 2014siRNA Screen of Microglia to Identify Neuroprotective Drug Targets in Parkinson´s Disease
Objective/Rationale:
Neuroinflammation is a fundamental process contributing to the death of neurons in Parkinson´s disease (PD). During this process, inflammatory microglia, which are the... -
Rapid Response Innovation Awards, 2014Mirtazapine as a Treatment for Pathological Gambling
Objective/Rationale:
Pramipexole (Mirapex®) is a drug that is effective at alleviating movement deficits associated with Parkinson’s disease. However, pramipexole can induce compulsive... -
Rapid Response Innovation Awards, 2014Pum2-mediated Translational Regulation of Alpha-synuclein mRNA Associated with Mitochondria
Objective/Rationale:
Aggregation of the protein alpha-synuclein and dysfunction of mitochondria (the powerhouse of the cell) are two critical components of Parkinson’s disease. We have... -
Research Grant, 2014Bioenergetic and Proteomic Profiling of PINK1, DJ-1 and Parkin Models
Objective/Rationale:
Some forms of familial Parkinson’s disease (PD) are due to mutations in the genes that code for the proteins PINK1, DJ-1 and parkin. These proteins have specific roles in the...
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Our funding programs support basic, translational and clinical research from academia and industry.