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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2013
    “Smart” Gene Therapy for Parkinson’s Disease

    Objective/Rationale:             
    Gene therapies for Parkinson’s disease (PD) aim to produce therapeutic proteins in diseased brain regions to promote neuron survival. Overexpression of these proteins...

  • Rapid Response Innovation Awards, 2013
    Tobacco Mosaic Virus Antibody and Risk of Parkinson’s Disease

    Objective/Rationale:             
    Cigarette smoking is associated with a lower risk of Parkinson’s disease (PD), but its protective mechanism is unknown. Tobacco mosaic virus (TMV), a plant pathogen...

  • Dyskinesia Challenge, 2013
    Oxytocin Effects on Levodopa-induced Dyskinesias

    Objective/Rationale:             
    The objective of this project is to describe the potential antidyskinetic properties of the hormone oxytocin. Oxytocin is found in brain areas that are negatively...

  • Research Grant, 2013
    Deep Sequencing Mass Spectrometry to Identify Biomarkers of Parkinson’s Disease in Cerebrospinal Fluid

    Objective/Rationale:
    Parkinson’s disease typically goes undetected until clinical diagnosis based on physical manifestations such as rigidity, resting tremor and slowness of movement.  Unfortunately...

  • Parkin Biology, 2013
    Deciphering and Exploiting the Neuroprotective Activity of Parkin

    Objective/Rationale:             
    Mutations in the Parkin gene are responsible for parkinsonism, and there is evidence that Parkin is inactivated in sporadic (cause unknown) Parkinson's disease...

  • Research Grant, 2013
    Effect of NPT088 in Alpha-synuclein Overexpressing Models

    Promising Outcomes of Original Grant:
    NeuroPhage technology simultaneously targets multiple misfolded proteins (e.g., alpha-synuclein, amyloid-beta, phosphorylated tau) involved in neurodegenerative...

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Our funding programs support basic, translational and clinical research from academia and industry.

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