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We are charting the path to a future free from Parkinson’s. Your support will get us there.

Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2018
    Charting a Path to Success for Clinical Trials in Patients with Inherited, GBA-linked Parkinson's Disease: PPMI Supplement

    Promising Outcomes of Original Grant:
    The original study is ongoing.

    Objectives for Supplemental Investigation:
    We aim to determine whether fatty molecules called sphingolipids can serve as biomarkers —…

  • Rapid Response Innovation Awards, 2014
    Optogenetics-based, Photo-switchable Model of Parkinson’s Disease for Drug Screening

    Objective/Rationale:
    Neurodegeneration has proven notoriously difficult to study. The main barrier to progress has been the challenging, heterogeneous nature of brain tissue. Optogenetics is a…

  • Access to Data and Biospecimens, 2014
    Defining Non-motor Phenotypes in Parkinson’s Disease and Novel Strategies for Diagnosis

    Objective/Rationale:
    Although Parkinson’s disease (PD) is diagnosed as a movement disorder, motor deficits are preceded by non-motor features including cognitive, cardiovascular, gastrointestinal…

  • Community Fast Track, 2003
    Regulation of Dopaminergic Pathways by Eph Family Receptors

    Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson’s disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also…

  • Biomarkers Across Neurodegenerative Diseases, 2014
    Cortical and Functional Distinctions in Alzheimer’s and Parkinson’s Diseases

    Study Rationale:
    Alzheimer’s disease (AD) and Parkinson’s disease (PD) are clinically distinct disorders, but their pathologies overlap considerably. Understanding how these overlaps relate to the two…

  • Alpha-synuclein Pathology, 2014
    Contrasting Pathological Versus Normal Alpha-synuclein Assemblies

    Study Rationale:                   
    Parkinson’s disease (PD) is characterized by Lewy bodies composed of the protein alpha-synuclein in dopamine-producing nerve cells. The protein aggregates are also…

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