The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2012Novel PD Tools: Generation of Posttranslationally Modified Alpha-synuclein
Objective/Rationale:
There is increasing evidence linking specific posttranslational modification (folding, cutting, etc. of proteins before maturation) and alpha-synuclein aggregation... -
Target Validation, 2012Validating Monoacylglycerol Lipase Inhibitors in Combatting Parkinson’s Disease
Objective/Rationale:
Chronic and persistent inflammation in the brain has been shown to be an underlying driver of Parkinson’s disease (PD). Anti-inflammatory strategies may be beneficial... -
Dyskinesia Challenge, 2012Evaluation of Cortical Resonant Oscillations as a Novel Target for Treatment of Dyskinesia
Objective/Rationale:
In our research we aim to identify changes in neuronal circuits that cause motor symptoms in Parkinson’s disease (PD) by recording neuronal activity in healthy and in... -
Rapid Response Innovation Awards, 2012Polyglutamine Repeats and Parkinson Disease
Objective/Rationale:
Trinucleotide repeat expansion is a gene mutation where the codons (the groups of DNA components that correspond to amino acids) exceed the maximum of a certain gene... -
Dyskinesia LEAPS, 2012Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Objective/Rationale:
Dyskinesia is a term used to describe involuntary movements that develop as side effects of dopamine drugs used to treat Parkinson's disease. Dyskinesias are frequent and... -
Biomarker Development, 2012Cleaved Cerebrospinal Fluid Proteins as Early Biomarkers for Detection of Parkinson’s Disease.
Objective/Rationale:
Parkinson’s disease is associated with the appearance of large, intracellular aggregates termed Lewy bodies consisting of damaged, truncated, aggregated and misfolded proteins...
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Our funding programs support basic, translational and clinical research from academia and industry.