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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Repositioning Drugs for PD, 2011
    Repositioning BCG Vaccination as an Immunostimulant for Slowing the Progression of PD

    Objective/Rationale: 
    We recently demonstrated that strong immune system stimulation created by treating pre-clinical models with a safe vaccine (called BCG) can have a restorative effect on...

  • Clinical Intervention Awards, 2011
    NH004 Films for Sialorrhea in PD Patients (2011)

    Objective/Rationale:
    Uncontrolled saliva or drooling (sialorrhea) is a socially debilitating condition with high prevalence in Parkinson’s disease (PD) patients. The NH004 treatment to control...

  • LRRK2, 2011
    Neuropathological tissue collection in LRRK2 Mutant carriers with and without PD

    Objective/Rationale:
    Neuropathological studies have been vital in Parkinson’s disease (PD) research. The gold-standard diagnosis of PD is confirmed at autopsy. In addition, information on key proteins...

  • MJFF Research Grant, 2011
    Generation of LRRK2 Lentiviral Vectors

    Objective/Rationale:
    Overexpression of LRRK2 in mammalian cells, either transient or as stable cell lines, has proven cumbersome and quite inefficient. This can be partly attributed to the large size...

  • Research Grant, 2011
    LRRK2 Effects on Neural Differentiation (Supplement 1)

    Promising Outcomes of Original Grant:
    Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) account for up to 13% of familial Parkinson's disease (PD) patients. One widely held...

  • Rapid Response Innovation Awards, 2011
    Assessing the Therapeutic Potential of iDA Neuronal Cells in Autologous Strategy

    Objective/Rationale:
    We have shown recently that three transcription factors can promote the conversion of skin fibroblasts into induced dopaminergic neuronal (iDAN) cells with remarkable functional...

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