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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Repositioning Drugs for PD, 2011
    Evaluation of a Specific DAT Inhibitor in Pre-clinical Models of Parkinson's Disease

    Objective/Rationale: 
    MLR-1017 is a psychostimulant drug used clinically for a variety of neuropsychiatric and other applications, but has never been tested in Parkinson’s disease (PD). Levodopa is a...

  • Research Grant, 2018
    The Effect of Psychological Stress on the Symptoms of Parkinson's Disease

    Study Rationale:
    Many people with Parkinson's disease (PD) experience chronic stress and associated disorders, such as depression, anxiety or both. Furthermore, many people with PD notice worsening of...

  • Improved Biomarkers and Clinical Outcome Measures, 2016
    Identification of Tear Biomarkers for Individuals with Parkinson's Disease

    Study Rationale:
    Prior to the appearance of classic movement abnormalities like tremor and slowness, those with Parkinson's suffer from non-motor symptoms, such as altered function of the...

  • LEAPS, 2011
    Supplement to 'Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD'

    Promising Outcomes of Original Grant:
    Activation or potentiation of metabotropic glutamate receptor 4 (mGluR4) is a promising new strategy for both Symptoms & Side Effects and disease-modifying...

  • Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2003
    A Trial of Low Frequency Repetitive Transcranial Magnetic Stimulation for Treatment of Dyskinesia

    Levodopa-induced dyskinesia (LID) is a major source of disability of many patients with Parkinson's disease (PD). LID may be associated with increased activity of the part of the brain that mediates...

  • Research Grant, 2022
    Identifying Novel Target Genes and Compounds for Controlling the Motor Symptoms of Parkinson’s Disease

    Study Rationale: Understanding neurological conditions has been among the most difficult challenges in modern medicine. The brain contains more than 86 billion nerve cells that form the neural...

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