The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2021Activity and Connectivity Drive Neuronal Vulnerability and Disease Progression in Parkinson’s Disease
Study Rationale:
Specific brain circuits that are highly melanized (build-up of the dark pigment neuromelanin) with age are primarily affected, particularly early, in Parkinson's disease. Models... -
Aligning Science Across Parkinson's, 2021Cortical Pathophysiology of Parkinsonism
Study Rationale:
The outer mantle of the brain, the cerebral cortex, plays a significant role in selecting and controlling movements. Changes in the activity of cortical neurons are key to disorders... -
Fall 2021 RFP: Expanding Biological Understanding of PD, 2021Using Human iPSC to Explore the Role of the STING Pathway in Parkinson's Disease
Study Rationale: Inflammation is recognized as a factor in the progression of Parkinson’s disease (PD). The PD-associated genes PINK1 and Parkin are involved in eliminating damaged cell components...
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Fall 2021 RFP: Outcome Measures, 2021Use of Image-enhancement Techniques to Assess Anatomical Changes in Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) has several subtypes. Identification of these subtypes in individuals with PD is important for understanding disease progression, developing new therapies...
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Fall 2021 RFP: Outcome Measures, 2022Using RNA from Extracellular Vesicles to Monitor RNA Changes in the Brain
Study Rationale: Our understanding of Parkinson’s disease (PD) would be significantly improved if we had a way to directly monitor disease development and progression in the brain. One approach is to...
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Fall 2021 RFP: Outcome Measures, 2021Exploring the Role of Faulty Protein Degradation as a Cause of Parkinson’s Disease
Study Rationale: For the brain to work efficiently, its cells have systems to clear out old proteins that are no longer needed or functional. When these protein-clearing systems fail, old proteins...
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Our funding programs support basic, translational and clinical research from academia and industry.