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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Shoring Up a Medical Chemistry Approach to Treating Parkinson’s Disease: The Bridge Initiative

    Study Rationale: The proteins parkin and GCase show a strong genetic link to Parkinson’s disease (PD) and are key players of biological pathways often disrupted in the disorder. This connection makes...

  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Investigating the Role of Repeat Expansions and Mitochondrial Dysfunction in Parkinson’s Disease

    Study Rationale: Both genetic mutations and exposure to environmental factors contribute to Parkinson’s disease (PD). Genetic risk for someone with PD could be due to multiple genes, different types...

  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Evaluating a Microbial Biomarker in Blood Samples for Parkinson’s Disease

    Study Rationale: Diagnosing Parkinson’s disease (PD) currently involves evaluation by movement disorder specialists and assessment based on physical examination and questionnaires. This approach is...

  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Using Data from the LEAPS Project to Improve the Accuracy of Assays that Measure Alpha-synuclein

    Study Rationale: The scientific and clinical research community working on Parkinson’s disease (PD) is in need of biomarkers to facilitate the monitoring of disease progression and efficacy of...

  • Research Grant, 2022
    Developing a Strategy to Determine Why Melanoma and Parkinson's Disease Occur Together

    Study Rationale: Having melanoma increases the risk for Parkinson's disease (PD)—and vice versa. The cellular basis for this association is not known. To identify the key cellular events that enhance...

  • Expanding Biological Understanding of Parkinson's Disease, 2022
    Characterization of the Contributions of Alpha-synuclein and Tau Aggregation in a Preclinical Model of Parkinson’s Disease Progression

    Study Rationale: Motor difficulties are not the only symptoms experienced by people with Parkinson’s disease (PD); up to 80% eventually develop dementia. This progression to dementia is associated...

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