The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson’s Pathway Molecular Data Analysis Program, 2022Investigating the Role of Repeat Expansions and Mitochondrial Dysfunction in Parkinson’s Disease
Study Rationale: Both genetic mutations and exposure to environmental factors contribute to Parkinson’s disease (PD). Genetic risk for someone with PD could be due to multiple genes, different types...
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Parkinson’s Pathway Molecular Data Analysis Program, 2022Evaluating a Microbial Biomarker in Blood Samples for Parkinson’s Disease
Study Rationale: Diagnosing Parkinson’s disease (PD) currently involves evaluation by movement disorder specialists and assessment based on physical examination and questionnaires. This approach is...
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Parkinson’s Pathway Molecular Data Analysis Program, 2022Using Data from the LEAPS Project to Improve the Accuracy of Assays that Measure Alpha-synuclein
Study Rationale: The scientific and clinical research community working on Parkinson’s disease (PD) is in need of biomarkers to facilitate the monitoring of disease progression and efficacy of...
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Research Grant, 2022Developing a Strategy to Determine Why Melanoma and Parkinson's Disease Occur Together
Study Rationale: Having melanoma increases the risk for Parkinson's disease (PD)—and vice versa. The cellular basis for this association is not known. To identify the key cellular events that enhance...
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Expanding Biological Understanding of Parkinson's Disease, 2022Characterization of the Contributions of Alpha-synuclein and Tau Aggregation in a Preclinical Model of Parkinson’s Disease Progression
Study Rationale: Motor difficulties are not the only symptoms experienced by people with Parkinson’s disease (PD); up to 80% eventually develop dementia. This progression to dementia is associated...
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Target Advancement Program, 2022Mining for Protein Aberrations in Parkinson’s Disease Using Large-Scale Protein Databases
Study Rationale: Deficient clearance of misfolded alpha-synuclein aggregates contributes to the pathology of Parkinson’s disease (PD). But broader disturbances in proteostasis—the balanced production...
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Our funding programs support basic, translational and clinical research from academia and industry.