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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Self-reported Perceptions and Self-reported Outcomes on Motor and Non-motor Symptoms in the Parkinson's Disease Continuum: A Systematic Review of Mixed Methods

    Study Rationale: People are unique in the way they experience quality of life. Throughout the progression of Parkinson's disease, patients and their care partners have different perceptions of motor...

  • Spring 2022 RFP: Proof-of-Concept Testing of PD Therapeutics, 2022
    Identification and Quantification of Parkinson’s Disease Progression Using Digital Measures from a Wrist-worn Wearable Device - a Retrospective Study

    Study Rationale: The combination of digital measures and machine learning (ML) holds great promise for improving critical aspects of Parkinson’s disease (PD) care, practice and research. Earlier PD...

  • Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2023
    (Supplement) Testing the Neuroprotective Efficacy of Modulating the Lysosomal Gene Atp6v0a1

    Study Rationale: The lysosome is a part of a cell involved in degrading and recycling proteins and other large molecules. Parkinson's disease (PD) is linked to lysosomal dysfunction. In this study, we...

  • Research Grant, 2023
    A Phase I Retest Study of Imaging Tracer MODAG-005 in Parkinson’s Disease, Multiple System Atrophy and Healthy Volunteers

    Study Rationale: In many neurodegenerative disorders, including Parkinson’s disease (PD) and (MSA), the protein alpha-synuclein is structurally altered and forms aggregates in the brain. These...

  • Research Grant
    (Supplement) Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson’s Disease

    Study Rationale: Most people with Parkinson’s disease (PD) develop voice and speech problems at some point during the course of the disease. Such problems, collectively known as the motor speech...

  • Research Grant, 2023
    Leveraging Gene Expression Data to Redefine Parkinson’s Disease and the Pathways Driving Disease in Different Individuals

    Study Rationale: People with Parkinson’s disease (PD) share some common problems, such as stiffness, slowness of movement and tremors. However, these symptoms vary in severity, and individuals often...

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