The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson's Pathway Biomarkers, 2021Phospho-proteome Analysis of PBMCs in LRRK2 Mutation Carriers: Expansion & Validation of Findings of the Barcelona LRRK2 Biorepository
Study Rationale: We established a biorepository of blood cells from G2019S LRRK2-PD patients recruited at the Hospital Clínic de Barcelona (Barcelona). Using this cohort, we performed a phospho...
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Lysosomal Biomarkers Program, 2023Validating Measurements of Peripheral GCase Longitudinally Under Clinical Trial Conditions
Study Rationale: An enzyme known as GCase is a key protein that stops working properly in people with Parkinson’s disease (PD). However, determining exactly how impaired the enzyme’s activity might...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Effect of SAR-CoV-2 on Experimental Parkinsonism in a Preclinical Model of Parkinson’s Disease
Study Rationale: Approximately 16.5 million people have been infected with the SARS-CoV2 virus. While primarily a respiratory virus, clinical observations indicate that in many cases, infection is...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Analysis of the Lysosomal Lipid Metabolism Pathway and Other Pathways, Subgroups and Stages in Parkinson’s Disease
Study Rationale: Lysosomes are cellular compartments involved in clearing molecular debris. Several genes that work in the lysosome, including GBA1, GALC, SMPD1 and others, are known to be involved in...
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2022: Accelerated Therapeutics Program, 2024(SUPPLEMENT) Small Molecule Mitochondrial Modulators for the Treatment of Parkinson's Disease
Study Rationale: Mitochondrial dysfunction is a crucial driver of the initiation and progression of Parkinson’s disease (PD). Mitochondria are structures that produce cellular energy, and in neurons...
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Research Grant, 2023Construction of a Library of Digital Technologies for Use in Research and Care of Parkinson’s Disease
Study Rationale: The past decade has seen enormous growth in commercially available digital technologies — including sensors, devices and smartphone apps — for the detection and monitoring of...
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Our funding programs support basic, translational and clinical research from academia and industry.