The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2024Developing an Open-access Repository of High-quality Digital Measurement Tools for Use in Parkinson’s Disease Research and Care
The Library of Digital Measurement Products
Study Rationale: This study will bring together leaders in Parkinson’s disease (PD) and digital health innovation and measurement to develop and maintain...
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2022: Accelerated Therapeutics Program, 2024(SUPPLEMENT) Small Molecule Mitochondrial Modulators for the Treatment of Parkinson's Disease
Study Rationale: Mitochondrial dysfunction is a crucial driver of the initiation and progression of Parkinson’s disease (PD). Mitochondria are structures that produce cellular energy, and in neurons...
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Parkinson’s Disease Therapeutics Pipeline Program, 2024Assessment of IRL757 for the Treatment of Apathy in Parkinson's Disease
Study Rationale: People with Parkinson’s disease (PD) frequently develop a loss of motivation and initiative. Such apathy can be burdensome for patients and their families and caregivers and is...
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Alpha-Synuclein Post-Translational Modifications Quantification Program, 2024Development of anAssay for Quantification of Alpha-synuclein and its Modifications
Study Rationale: Many studies have shown that a protein called alpha-synuclein is abnormal in Parkinson's disease (PD), forming toxic aggregates that move through the brain and cause neuronal cell...
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Research Grant, 2024Discovery of PET Tracers for Measuring Alpha-synuclein
Study Rationale: The discovery of new treatments for Parkinson’s disease (PD) has been slowed by the amount of time (years) it takes to determine whether a drug was effective in a clinical trial. New...
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2022: Accelerated Therapeutics Program, 2024(SUPPLEMENT) Innovative Therapies for Parkinson’s Disease Through a Novel, Unexploited Gene Expression Mechanism Rooted in Human Genetics Enabling a Precision-medicine Approach
Study Rationale: Parkinson’s disease (PD) and Alzheimer’s disease (AD) are neurodegenerative disorders caused by an accumulation of protein aggregates that leads to cell death. Genetic studies suggest...
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Our funding programs support basic, translational and clinical research from academia and industry.