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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2021
    Comparing the Effectiveness of Two Imaging Methods for Monitoring the Progression of Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease robs the brain of dopamine, a neurochemical needed for normal movement and cognition. A variety of imaging methods can be used to monitor the brain’s dopamine...

  • Biomarkers, 2021
    Measurement of Mitochondrial DNA in Early Stages of Parkinson’s Disease

    Study Rationale:    
    People with a form of idiopathic REM sleep behavior disorder (iRBD) experience nightmares and lash out physically during a stage of sleep when the body's muscles are normally...

  • Therapeutic Pipeline Program, 2021
    Pharmacological Targeting of Inflammation to Modify Disease Progression in Pre-clinical Models of Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by pronounced brain inflammation. Despite being the most common movement disorder to date, no therapy...

  • Target Advancement Program, 2021
    Exploring the Role of FAIM, an Inhibitor of Cell Death, in Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease (PD) is characterized by the degeneration of dopamine-producing neurons in the brain. We recently discovered that a protein called FAIM can protect neurons from...

  • Therapeutic Pipeline Program, 2021
    Novel Inhibitors of Cell Death for the Treatment of People with Parkinson’s Disease

    Study Rationale: 
    Subcellular structures called mitochondria perform many critical activities for brain cells. They generate enormous amounts of energy and remove the calcium that floods into neurons...

  • Biomarkers, 2021
    The Development of Novel Probes for Imaging Glucocerebrosidase Activity in Parkinson’s Disease

    Study Rationale:       
    Mutations that disable glucocerebrosidase (GBA), a protein that strips sugars from molecules in the membranes of brain cells, are associated with Parkinson’s disease (PD)...

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