The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2011Multi-tracer positron emission tomography (PET) functional imaging as a tool to assess the relevance of rodent LRRK2 models to the human neurochemical phenotype associated with LRRK2 mutations related Parkinsonism
Promising Outcomes of Original Grant:
The goals of the original grant were to develop PET (a non invasive imaging technique used in the study of human Parkinson’s disease ) –derived measures of... -
LRRK2, 2011LRRK2 Role on Auto-Antibody Production by Human B Cells
Objective/Rationale:
LRRK2 expression has been demonstrated in the brain and several organs, including the thymus and spleen, which are major immune system organs for B and T lymphocyte maturation... -
Rapid Response Innovation Awards, 2011Functional Characterization of ATP13A2, a P-type Transport ATPase Involved in Neurodegeneration
Objective/Rationale:
Mutations in the ATP13A2 gene lead to the Kufor-Rakeb syndrome, a severe early-onset form of Parkinson’s disease (PD) with dementia. The ATP13A2 protein is targeted to cellular... -
Resource: Utilizing DATATOP Biospecimens, 2011Using Human Cerebrospinal Fluid Samples Collected in DATATOP Study for Biomarker Validation in Patients with Parkinson disease
Objective/Rationale:
One of the major challenges in biomarker discovery/validation for Parkinson's disease (PD) is to define their utility in PD progression. This task is best tackled with the... -
Rapid Response Innovation Awards, 2011Unlimited Discovery of Non-Coding, Regulatory RNAs and Aberrant Splicing in Parkinson's
Objective/Rationale:
The recent discovery of a hidden universe of regulatory, non-coding transcripts and previously unknown variants of protein-coding transcripts is challenging conventional thinking... -
MJFF Research Grant, 2011Validation of Lysosomal Enzymes Assay in CSF - One-year Extension of the RRIA: CSF Lysosomal Hydrolases' Activity as Possible Marker of Parkinson's Disease
Promising Outcomes of Original Grant:
To date, there is no accepted diagnostic test based on biochemical analysis of blood or cerebrospinal fluid (CSF) for clinical diagnosis of PD. Recent studies...
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Our funding programs support basic, translational and clinical research from academia and industry.