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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2013
    Evaluation of Targeted Plasticity Therapy as a Treatment for Motor Dysfunction in Parkinson’s Disease

    Objective/Rationale:             

    Deterioration of motor function is a debilitating symptom of Parkinson’s disease (PD). We have recently developed a novel method that utilizes stimulation of the...

  • Research Grant, 2010
    Longitudinal Follow-Up of Clinical and Neuroimaging Signs and Biomarkers in Symptoms & Side Effects and aSymptoms & Side Effects LRRK2 Mutation Carriers in Comparison to Idiopathic PD and Controls

    Objective/Rationale
    Parkinson’s disease (PD) is a common neurodegenerative disease that leads to progressive motor impairment as well as autonomic and cognitive disturbances. The cause of most of...

  • Rapid Response Innovation Awards, 2014
    Disease-modifying Potential of Nortriptyline in Parkinson’s Disease

    Objective/Rationale:             
    Aggregation of the protein alpha-synuclein is toxic to dopamine neurons. Therefore, a compound that reduces or clears this protein could be a viable therapeutic option...

  • Defining Cognitive Phenotypes of Parkinson’s Disease, 2011
    Predicting Cognitive Profiles in Parkinson's Disease: A Multimodal Approach

    Objective/Rationale:
    Our proposal aims to determine the optimum combination of techniques to detect rate of cognitive decline in people with newly diagnosed Parkinson’s disease (PD). We will apply...

  • Therapeutics Development Initiative, 2008
    Development of ERb agonists for the treatment of Parkinson's Disease

    Objective/Rationale:
    Estrogens modulate many cerebral functions such as mental state, mood, cognition and locomotion. Data indicate that estrogens may slow down the development and progression of PD...

  • Clinical Intervention Awards, 2007
    Serotonin and Sleep Disordered Breathing in Parkinson Disease

    Objective/Rationale:
    Sleep related problems are a major cause of impairment in Parkinson's disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing...

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