The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2020Adaptive Deep Brain Stimulation for Gait Retraining in Parkinson's Disease
Study Rationale:
Walking impairment in people with Parkinson’s disease (PD) often arises from difficulties in coordinating leg movements in response to environment changes. Continuous stimulation of... -
Alpha-Synuclein Imaging, 2020PET Imaging Probe Development for Alpha-synuclein
Study Rationale:
Alpha-synuclein is a protein that can clump to form Lewy bodies and lewy neurites, which are a hallmark of Parkinson's disease. Being able to identify these clumps in living patients... -
Therapeutic Pipeline Program, 2020Pre-clinical Development of Compounds that Modulate Mitophagy through Regulation of the Mitochondrial GTPase Miro1
Study Rationale:
Evidence indicates that mitochondrial dysfunction is a significant contributor to Parkinson’s disease, with the majority of patients exhibiting a shared defect in the processing of... -
Alpha-Synuclein Imaging, 2020Alpha-Synuclein PET Tracer Discovery
Study Rationale:
The discovery of new treatments for Parkinson’s disease has been slowed by the time it takes to answer the question “did a drug work” in a clinical trial. Tests that can assess... -
Therapeutic Pipeline Program, 2020Pregnenolone for the Treatment of L-DOPA-induced Dyskinesia in Parkinson's disease
Study Rationale:
Neurosteroids are substances that occur naturally in the brain and help regulate and modulate the activity of brain cells. In previous studies, the investigators demonstrated that... -
Access to Data and Biospecimens, 2020Development of a Biomarker Platform for Parkinson’s Disease Using Patient-derived Cells
Study Rationale:
Inadequate understanding of how Parkinson's disease develops is a major roadblock in developing effective therapeutics and methods to diagnose the disease earlier. This project...
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Our funding programs support basic, translational and clinical research from academia and industry.