The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2020In Vivo Approach to Elucidate the Pathobiology of Parkinson’s-associated Genes Using Human Diseased Neurons
Study Rationale:
Several genes are known to be associated with Parkinson’s disease, although how they impact the disease process is not fully understood. Here we will use stem cells from patients in... -
Aligning Science Across Parkinson's, 2020Senescence in Parkinson’s Disease and Related Disorders
Study Rationale:
While aging is the greatest risk factor for development of Parkinson’s disease (PD), how aging promotes PD is not fully understood. Examining the role of cellular senescence... -
Aligning Science Across Parkinson's, 2020Mechanisms of Mitochondrial Damage Control by PINK1 and Parkin
Study Rationale:
Mitochondria are tiny power-generating stations within all cells, including neurons. They are vital energy producers, but when things go wrong, they can spew toxic materials and... -
Aligning Science Across Parkinson's, 2020Activation of Transposable Elements as a Trigger of Neuroinflammation in Parkinson’s Disease
Study Rationale:
Inflammation is a common event in Parkinson’s disease (PD), but its source remains unclear. There are many candidates that could cause inflammation in the nervous system. One likely... -
Aligning Science Across Parkinson's, 2020From Cancer Associations to Altered Immunity in the Pathogenesis of Parkinson’s Disease
Study Rationale:
Parkinson’s disease is characterized by premature death of dopamine-producing neurons in the brain; cancer is characterized by overgrowth of dividing cells. Despite being very... -
Aligning Science Across Parkinson's, 2020Adaptive Immunity in the Etiology and Progression of Parkinson’s Disease
Study Rationale:
Research from our team indicates that immune cells may play central roles in the development of Parkinson’s disease (PD). In PD, certain types of nerve cells can activate specific...
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Our funding programs support basic, translational and clinical research from academia and industry.