The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2019Computer Simulation of LRRK2 and GBA Interactions to Identify Therapeutic Targets for Parkinson's Disease
Promising Outcomes of Original Grant:
Our original project aimed to create a computer simulation of biological pathways involved in Parkinson's disease and how genetic mutations in LRRK2 can change... -
Research Grant, 2019Developing an Alpha-synuclein Imaging Agent
Study Rationale:
The goal of this study is to develop an imaging tool (a radiotracer) that could be used to show the protein alpha-synuclein in the brains of living people with a brain scan call a... -
Alpha-Synuclein Biology and Therapies, 2019How Does Alpha-synuclein Cause Neurodegeneration?
Study Rationale:
The protein alpha-synuclein has a central, causative role in Parkinson's disease, but we do not understand how it contributes to cell degeneration. Mutations in the gene (SNCA) that... -
Research Grant, 2019Interpretation of Accelerometer Data with Deep Learning
Study Rationale:
In-home monitoring of the severity of Parkinson's disease (PD) may help guide therapeutic decisions and prevent life-threatening falls. Deep learning is the state-of-the-art tool for... -
Research Grant, 2019Parkin-activating Small Molecules in a Model of Mitophagy
Study Rationale:
The protein parkin plays a critical role in the health and maintenance of the brain cells that make dopamine, which degenerate in Parkinson's disease. Scientific evidence shows that... -
GBA Biology and Therapies, 2019Inflammation in People with Parkinson's and a GBA Mutation and in Their Unaffected Relatives
Study Rationale:
Parkinson's is a complex disease combining genetic, environmental and inflammatory causes. Mutations in the GBA gene are a leading genetic contributor to Parkinson's disease. While...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.