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The Parkinson's Progression Markers Initiative is our landmark study launched in 2010 to deepen knowledge of Parkinson's and to better understand its onset and progression to speed the development of new treatments. Learn the latest news from the study here.


  • Research Testing

    PPMI Dispatch: Identifying Differences in Disease Profiles and Impact on Quality of Life

    Findings from the Parkinson’s Progression Markers Initiative show differences in symptoms among participants with genetic mutations and compare automatic functions over time with quality of life.
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  • Scientist in Lab

    PPMI Dispatch: Streamlined Data, Genetic Indicators and Cognitive Decline Predictors

    Data from the Parkinson’s Progression Markers Initiative has been downloaded more than 5 million times. View recent findings and updates from the study.
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  • Theresa Lin, Sarah Simon, Katherine Leaver, Sonya Elango, Susan Bressman, Deborah Raymond, Rachel Saunders-Pullman

    Research Community Thanks Parkinson’s Study Participants

    Research volunteers advance understanding and treatment of Parkinson’s disease. Foundation staff and partners recently thanked local participants.
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  • Samples in the lab.

    PPMI Dispatch: Early Signs of Disease and Striking Some Potential Markers

    Findings from the Parkinson’s Progression Markers Initiative show subtle symptoms in mutation carriers and that motor subtypes change with time and therapy.
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  • Ask the PhD: Big Data, Better Answers

    In our latest Ask the PhD video, two MJFF staff scientists talk about why data matters in Parkinson’s.
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  • 'Scientific American' Talks LRRK2 and Parkinson's Research with MJFF CEO Todd Sherer

    PPMI Dispatch: Findings and New Initiatives Shared at the Annual Meeting

    Investigators from the landmark Parkinson’s Progression Markers Initiative shared recent findings and initiatives to better define, measure and treat the disease.
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