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The Parkinson's Progression Markers Initiative is our landmark study launched in 2010 to deepen knowledge of Parkinson's and to better understand its onset and progression to speed the development of new treatments. Learn the latest news from the study here.


  • PPMI Shows Protein Levels Lower in Spinal Fluid of People with Parkinson's

    PPMI Dispatch: Capturing the Parkinson's Experience Day to Day and Over Years

    The Parkinson's Progression Markers Initiative is gathering and analyzing data on the experience of Parkinson's to better define and measure the disease.
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  • Close up of hand holding test tube

    Could an Antioxidant Protect LRRK2 Carriers from Parkinson's?

    A new study suggests urate may protect the genetic mutation that increases PD risk.
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  • Testing Materials

    PPMI Dispatch: The Study Enters a New Phase

    The study completed enrollment and met the ambitious goal of enrolling 1,400 participants, including 600 with rare genetic mutations.
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  • Brain Commons Logo

    The Michael J. Fox Foundation Joins BRAIN Commons to Accelerate Brain Disease Research

    MJFF joins BRAIN Commons, a data sharing platform for data analyzes in PD, to help fuel collaborative science.
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  • Scientist in Lab

    The Appendix and Parkinson's: 'It's a Piece to the Puzzle'

    Rachel Dolhun, MD, vice president of medical communication at the Foundation comments on these findings.
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    Parkinson's Research: PPMI Clinical Study

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