Günter U. Höglinger is Professor and Director of the Department of Neurology at Ludwig Maximilian University of Munich and an affiliated scientist of the German Center for Neurodegenerative Disorders. He is a clinician-scientist whose research focuses on neurodegenerative diseases driven by pathological protein aggregation, particularly alpha-synucleinopathies and tauopathies. Over two decades, he has established a highly translational research program integrating large patient cohorts, deep clinical phenotyping, biofluid and imaging biomarkers, and mechanistic studies in cellular and animal models.
Höglinger leads major national and international biomarker initiatives and multi-omics consortia aimed at identifying molecular signatures of disease progression and treatment response. His work has been central to defining biologically informed diagnostic criteria and biomarker-driven clinical trial strategies. Embedded in interdisciplinary networks such as the Munich Cluster for Systems Neurology, he is strongly committed to collaborative team science, open data sharing, and accelerating disease-modifying therapies in Parkinson’s disease and related disorders.
Associated Grants
-
Deciphering the Aggregatome: Unraveling Alpha-Synuclein Seeding Drivers in Parkinson’s Disease Across Human Biomaterials
2026
-
BIOLOGY IS THE DISEASE: Identifying Biological Endophenotypes Based on Alpha-synuclein and AD Pathology Profiles and Evaluate NSD-ISS Stage 3-6
2025