Sean Simmons is currently a senior computational scientist at the Broad Institute, where he has been part of the Levin Lab in the Stanley Center for Psychiatric Research for 9+ years. During this time he has led the analysis of data for many projects related to diseases of the brain, including schizophrenia, developmental disorders, and neurodegenerative diseases likes Parkinson’s. This work has had a particular focus on single-cell and single-nucleus RNA-seq. Prior to his time at the Broad he was a PhD student in the mathematics department at MIT in the Berger lab and a joint Post Doc between the Berger lab at MIT and the Sahinalp lab at SFU. While there he worked on numerous projects focused on human genetics, with a particular focus on developing privacy preserving methods for GWAS.
Associated Grants
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A Meta-Analysis of Single Nucleus Allele Specific Expression to Investigate Parkinson's Disease
2025