Stefan Semrau, PhD

Dr. Stefan Semrau is the Senior Director of Computational Biology and Data Sciences at the JAX-NYSCF Collaborative. After obtaining a PhD in biophysics from Leiden University in the Netherlands, he completed postdoctoral training at the Massachusetts Institute of Technology and the Whitehead Institute where he pioneered single-cell imaging and sequencing technologies to study in vitro models of cancer and stem cell differentiation. With an independent research group at Leiden University, Dr. Semrau developed stem cell-derived models of embryonic development as well as computational tools for the molecular characterization of those models. His team at JAX-NYSCF leverages various types of experimental data, ranging from high content imaging to (single-cell) gene expression and (epi)genomics, to find disease signatures in stem cell-derived in vitro models. Dr. Semrau’s team has worked on a variety of diseases including cancer, Alzheimer’s disease and Parkinson’s disease.