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Stephen J. Gold, PhD

Research Assistant Professor at Department of Pharmacology and Neuroscience at University of North Texas Health Sciences Center (UNT

Stephen J. Gold, PhD, received his BS in Psychology from Wayne State University in Detroit, Michigan in 1987. From there Dr. Gold moved to the Department of Psychobiology Graduate Program at the University of California, Irvine. Dr. Gold completed a PhD thesis in the laboratory of Dr. Christine Gall in 1996, where his research focused on the anatomical distribution and regulation of ionotropic glutamate receptors. Dr. Gold then secured a postdoctoral position in the laboratory of Dr. Eric Nestler in the Department of Psychiatry at the Yale University Medical School and Connecticut Mental Health Center. Under Dr. Nestler's mentorship, Dr. Gold transitioned to research on the role of G protein coupled receptor modulatory proteins in brain function. Specifically, Dr. Gold's research has elucidated the role of the Regulator of G protein Signaling (RGS) family of GTPase activating proteins in psychiatric and neurological disease. Dr. Gold's productive postdoctoral training led to an assistant professorship in the Department of Psychiatry at UT Southwestern Medical Center at Dallas, Texas. Dr. Gold's current research program focuses on 2 RGS proteins, RGS9-2 and RGS10. RGS9-2 is a key modulator of signaling by the D2 class of dopamine receptors. Current research in Dr. Gold's lab seeks to identify the mechanism via which RGS9-2 inhibits the development of L-dopa-induced dyskinesias. In addition, his research aims to understand the mechanism by which RGS10 exerts its anxiolytic effects. Dr. Gold has successfully competed for several privately funded research grants including two Young Investigator Awards from the National Alliance for Research on Schizophrenia and Depression and a Beginning Grant-in-Aid from the American Heart Association Texas Affiliate. In addition, Dr. Gold's research has been funded via program project grants from NIDA and NIMH.

Associated Grants

  • D3 Receptor Selective Drugs for Parkinson's Dyskinesia

    2006


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