MJFF Publications

2451 - 2460 of 6515 Results

Title

Year

Year
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2020

The recent failure of the PROMESA clinical trial for multiple system atrophy raises the question—are polyphenols a viable therapeutic option against proteinopathies?
2020

Summary Details

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Title: The recent failure of the PROMESA clinical trial for multiple system atrophy raises the question—are polyphenols a viable therapeutic option against proteinopathies?

Author(s): Gal Bitan

Journal Name: Annals of Translational Medicine

Publisher: AME Publishing Company

Vol: 8

Issue #: 11

Start Page: 719

End Page: 719

Publication Date: 2020-06-01

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.21037/atm.2020.01.117

Best OA location URL: https://atm.amegroups.com/article/viewFile/35635/pdf

Citation Count: 11
Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death
2020

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Title: Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death

Author(s): Hyojung Kim, Jisoo Park, Hojin Kang, Seung Pil Yun, Yun‐Song Lee, Yun‐Il Lee, Yunjong Lee

Journal Name: Science Signaling

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 13

Issue #: 663

Start Page:

End Page:

Publication Date: 2020-12-22

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/scisignal.aax7119

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7909008

Citation Count: 44
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
2020

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Title: Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

Author(s): Mathieu Bourdenx, Aurélien Nioche, Sandra Doveró, Marie-Laure Arotçarena, Sandrine Camus, Grégory Porras, Marie-Laure Thiolat, N. P. Rougier, Alice Prigent, P. Aubert, Sylvain Bohic, Christophe Sandt, Florent Laferrière, Évelyne Doudnikoff, Niels Kruse, Brit Mollenhauer, Salvatore Novello, Michele Morari, Thierry Lesté-Lasserre, Inés Trigo‐Damas, Michel Goillandeau, Céline Perier, Cristina Estrada, Nuria García‐Carrillo, Ariadna Recasens, Nishant N. Vaikath, Omar M. A. El‐Agnaf, María Trinidad Herrero, Pascal Derkinderen, Miquel Vila, José Á. Obeso, Benjamin Dehay, Erwan Bézard

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 6

Issue #: 20

Start Page: eaaz9165

End Page: eaaz9165

Publication Date: 2020-05-13

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/sciadv.aaz9165

Best OA location URL: https://advances.sciencemag.org/content/advances/6/20/eaaz9165.full.pdf

Citation Count: 59
Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
2020

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Title: Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease

Author(s): Lenora Higginbotham, Lingyan Ping, Eric B. Dammer, Duc M. Duong, Maotian Zhou, Marla Gearing, Cheyenne Hurst, Jonathan D. Glass, Stewart A. Factor, Erik C. B. Johnson, Ihab Hajjar, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 6

Issue #: 43

Start Page:

End Page:

Publication Date: 2020-10-21

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.1126/sciadv.aaz9360

Best OA location URL: https://advances.sciencemag.org/content/advances/6/43/eaaz9360.full.pdf

Citation Count: 382
Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor
2020

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Title: Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor

Author(s): Enrico Opri, Stephanie Cernera, Rene Molina, Robert S. Eisinger, Jackson Cagle, Leonardo Almeida, Timothy Denison, Michael S. Okun, Kelly D. Foote, Aysegul Gunduz

Journal Name: Science Translational Medicine

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 12

Issue #: 572

Start Page:

End Page:

Publication Date: 2020-12-02

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/scitranslmed.aay7680

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8182660

Citation Count: 153
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease
2020

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Title: A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease

Author(s): Ibrahim Boussaad, Carolin D. Obermaier, Zoé Hanss, Dheeraj Reddy Bobbili, Silvia Bolognin, Enrico Glaab, Katarzyna Wicher, Nicole Weisschuh, Laura De Conti, Caroline May, Florian Giesert, Dajana Großmann, Annika Lambert, Susanne Kirchen, Maria Biryukov, Lena F. Burbulla, François Massart, Jill Bohler, Gérald Cruciani, Benjamin Schmid, Annerose Kurz-Drexler, Patrick May, Stefano Duga, Christine Klein, Jens C. Schwamborn, Katrin Marcus, Dirk Woitalla, Daniela M. Vogt Weisenhorn, Wolfgang Wurst, Marco Baralle, Dimitri Krainc, Thomas Gasser, Bernd Wissinger, Rejko Krüger

Journal Name: Science Translational Medicine

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 12

Issue #: 560

Start Page:

End Page:

Publication Date: 2020-09-09

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/scitranslmed.aau3960

Best OA location URL: http://orbilu.uni.lu/handle/10993/44767

Citation Count: 65
A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels
2020

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Title: A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels

Author(s): Garry Cooper, Soosung Kang, Tamara Perez‐Rosello, Jaime N. Guzmán, Daniel J. Galtieri, Zhong Xie, Jyothisri Kondapalli, Jack Mordell, Richard B. Silverman, D. James Surmeier

Journal Name: ACS Chemical Biology

Publisher: American Chemical Society (ACS)

Vol: 15

Issue #: 9

Start Page: 2539

End Page: 2550

Publication Date: 2020-09-03

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1021/acschembio.0c00577

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7502546

Citation Count: 17
Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
2020

Summary Details

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Title: Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro

Author(s): Pierluigi Valente, Darya Kiryushko, Silvio Sacchetti, Pedro Machado, Claire M. Cobley, Vincenzo Mangini, Alexandra E. Porter, Joachim P. Spatz, Roland A. Fleck, Fabio Benfenati, Roberto Fiammengo

Journal Name: ACS Nano

Publisher: American Chemical Society (ACS)

Vol: 14

Issue #: 6

Start Page: 6866

End Page: 6877

Publication Date: 2020-06-08

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1021/acsnano.0c00866

Best OA location URL: https://ndownloader.figstatic.com/files/22969427

Citation Count: 15
Virus Bioresistor (VBR) for Detection of Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute
2020

Summary Details

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Title: Virus Bioresistor (VBR) for Detection of Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute

Author(s): Apurva Bhasin, Emily C. Sanders, Joshua Ziegler, Jeffrey S. Briggs, Nicholas P. Drago, Aisha Attar, Alicia M. Santos, Marie Y. True, Alana F. Ogata, Debora V. Yoon, Sudipta Majumdar, Andrew Wheat, Shae V. Patterson, Gregory A. Weiss, Reginald M. Penner

Journal Name: Analytical Chemistry

Publisher: American Chemical Society (ACS)

Vol: 92

Issue #: 9

Start Page: 6654

End Page: 6666

Publication Date: 2020-04-06

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1021/acs.analchem.0c00534

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7266010

Citation Count: 30
Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils
2020

Summary Details

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Title: Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils

Author(s): Dan E. Adolfsson, Mohit Tyagi, Pardeep Singh, Adrian Deuschmann, Jörgen Ådén, Anna L. Gharibyan, Sanduni Wasana Jayaweera, Anders E. G. Lindgren, Anders Olofsson, Fredrik Almqvist

Journal Name: The Journal of Organic Chemistry

Publisher: American Chemical Society (ACS)

Vol: 85

Issue #: 21

Start Page: 14174

End Page: 14189

Publication Date: 2020-10-25

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1021/acs.joc.0c01699

Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c01699

Citation Count: 23

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