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  • Alpha synuclein overexpression can drive microbiome dysbiosis in mice
    2025
    OPEN
    Title: Alpha synuclein overexpression can drive microbiome dysbiosis in mice
    Author(s): Timothy R. Sampson, Zachary D. Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-024-82139-7
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    Citation Count: 0
  • Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
    2025
    OPEN
    Title: Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
    Author(s): Kenneth Marek, David Russell, Luis Concha‐Marambio, Seung Ho Choi, Danna Jennings, Michael C. Brumm, Christopher S. Coffey, Ethan G. Brown, John Seibyl, Matthew Stern, Claudio Soto, Andrew Siderowf
    Journal Name: eBioMedicine
    Publisher: Elsevier BV
    Vol: 112
    Issue #:
    Start Page: 105567
    End Page: 105567
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.ebiom.2025.105567
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    Citation Count: 0
  • Lewy body diseases and the gut
    2025
    OPEN
    Title: Lewy body diseases and the gut
    Author(s): Timothy R. Sampson, Malú G. Tansey, Andrew B. West, Rodger A. Liddle
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 20
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-025-00804-5
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    Citation Count: 0
  • Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment
    2025
    OPEN
    Title: Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment
    Author(s): Katharina Bolsewig, Eline A.J. Willemse, Pascual Sánchez‐Juan, Alberto Rábano, Minerva Martínez, James D. Doecke, G. Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors in ‘t Veld, Niklas Mattsson, Kateřina Veverová, Christopher J. Fowler, Lynn Boonkamp, Marleen J.A. Koel‐Simmelink, Zulaiga Hussainali, Daimy N. Ruiters, Lorenzo Gaetani, Andrea Toja, Juan Fortea, Yolande A.L. Pijnenburg, Afina W. Lemstra, Wiesje M. van der Flier, Jakub Hort, Markus Otto, Oskar Hansson, Lucilla Parnetti, Colin L. Masters, Alberto Lléo, Charlotte E. Teunissen, Marta del Campo
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41467-025-56293-z
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    Citation Count: 0
  • Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain
    2025
    OPEN
    Title: Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain
    Author(s): Enrico Bagnoli, Yu‐En Lin, Sophie Burel, Ebsy Jaimon, Odetta Antico, Christos Themistokleous, Jonas Nikoloff, Sabrina Squires, Ilaria Morella, Jens O. Watzlawik, Fabienne C. Fiesel, Wolfdieter Springer, Francesca Tonelli, Paweł Lis, Simon P. Brooks, Stephen B. Dunnett, Riccardo Brambilla, Dario R. Alessi, Suzanne R. Pfeffer, Miratul M. K. Muqit
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 122
    Issue #: 5
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2412029122
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    Citation Count: 0
  • Identifying gait differences between Alzheimer's disease and dementia with Lewy bodies and their associations with regional amyloid deposition
    2025
    OPEN
    Title: Identifying gait differences between Alzheimer's disease and dementia with Lewy bodies and their associations with regional amyloid deposition
    Author(s): Salma Elasfar, Hajr Hameed, Bradley F. Boeve, Julie A. Fields, Clifford R. Jack, Kejal Kantarci, Erik K. St. Louis, Val J. Lowe, Ronald C. Petersen, Farwa Ali, Kaylena A. Ehgoetz Martens
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol: 21
    Issue #: 2
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/alz.14351
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    Citation Count: 0
  • Splicing accuracy varies across human introns, tissues, age and disease
    2025
    OPEN
    Title: Splicing accuracy varies across human introns, tissues, age and disease
    Author(s): Sonia García-Ruíz, David Zhang, Emil K. Gustavsson, G Rocamora-Perez, Melissa Grant‐Peters, Aine Fairbrother-Browne, Regina H. Reynolds, Jonathan Brenton, Ana Luisa Gil-Martínez, Zhongbo Chen, Donald C. Rio, Juan A. Botía, Sebastian Guelfi, Leonardo Collado‐Torres, Mina Ryten
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-024-55607-x
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    Citation Count: 0
  • Transcriptomics profiling of Parkinson’s disease progression subtypes reveals distinctive patterns of gene expression
    2025
    OPEN
    Title: Transcriptomics profiling of Parkinson’s disease progression subtypes reveals distinctive patterns of gene expression
    Author(s): Carlo Fabrizio, Andrea Termine, Carlo Caltagirone
    Journal Name: Journal of Central Nervous System Disease
    Publisher: SAGE Publications
    Vol: 17
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1177/11795735241286821
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    Citation Count: 0
  • Baseline liver fibrosis-4 score correlates to the progression of anxiety and cognitive impairment in patients with Parkinson’s disease
    2025
    OPEN
    Title: Baseline liver fibrosis-4 score correlates to the progression of anxiety and cognitive impairment in patients with Parkinson’s disease
    Author(s): Yongqing Cheng, Li Chen, Honghong Zhu, Yingchao Ge, Lei Li, Yan Guo, Xin Wang, San‐Lin You, Guojun He, Shouru Xue
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 17
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2025.1501319
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    Citation Count: 0
  • Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST
    2025
    OPEN
    Title: Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST
    Author(s): Felix Kraus, Yuchen He, Sharan Swarup, Katherine A. Overmyer, Yizhi Jiang, Johann Brenner, Cristina Capitanio, Anna Bieber, Annie Jen, Nicole M. Nightingale, Benton J. Anderson, Chan Lee, João A. Paulo, Ian R. Smith, Jürgen M. Plitzko, Steven P. Gygi, Brenda A. Schulman, Florian Wilfling, Joshua J. Coon, J. Wade Harper
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 11
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.adu5787
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    Citation Count: 0
  • Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
    2025
    OPEN
    Title: Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
    Author(s): D. Luke Fischer, Marissa Menard, Omar Abdelaziz, Nicholas M. Kanaan, Virginia G. Cobbs, Richard Kennedy, Geidy E. Serrano, Thomas G. Beach, Laura A. Volpicelli‐Daley
    Journal Name: Acta Neuropathologica Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1186/s40478-024-01913-w
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    Citation Count: 0
  • Iron deposition is associated with motor and non-motor network breakdown in parkinsonism
    2025
    OPEN
    Title: Iron deposition is associated with motor and non-motor network breakdown in parkinsonism
    Author(s): Fangda Leng, Yue Gao, Fan Li, Luhua Wei, Yunchuang Sun, Fang Liu, Ying Zhu, Jianxing Qiu, Zhaoxia Wang, Yiwei Zhang
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 16
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2024.1518155
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    Citation Count: 0
  • Differential Impact of Risk Factors for Cognitive Decline in Heterosexual and Sexual Minority Older Adults in England
    2025
    OPEN
    Title: Differential Impact of Risk Factors for Cognitive Decline in Heterosexual and Sexual Minority Older Adults in England
    Author(s): Riccardo Manca, Jason D. Flatt, Annalena Venneri
    Journal Name: Brain Sciences
    Publisher: MDPI AG
    Vol: 15
    Issue #: 1
    Start Page: 90
    End Page: 90
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/brainsci15010090
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    Citation Count: 0
  • The effect of polygenic risk score on PD risk and phenotype in LRRK2 G2019S and GBA1 carriers
    2025
    OPEN
    Title: The effect of polygenic risk score on PD risk and phenotype in LRRK2 G2019S and GBA1 carriers
    Author(s): Orly Goldstein, Shachar Shani, Mali Gana‐Weisz, Nadav Elkoshi, Fergal Casey, Yu Sun, Khyati Chandratre, Jesse M. Cedarbaum, Cornelis Blauwendraat, Anat Bar‐Shira, Avner Thaler, Tanya Gurevich, Anat Mirelman, Nir Giladi, Avi Orr‐Urtreger, Roy N. Alcalay
    Journal Name: Journal of Parkinson’s Disease
    Publisher: SAGE Publications
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1177/1877718x241310722
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    Citation Count: 0
  • Conducting Polymer Microelectrode Arrays for Simultaneous Electrophysiology and Advanced Brain Imaging
    2025
    OPEN
    Title: Conducting Polymer Microelectrode Arrays for Simultaneous Electrophysiology and Advanced Brain Imaging
    Author(s): Sagnik Middya, Alejandro Carnicer‐Lombarte, Stephen J. Sawiak, Sam Hilton, Vincenzo F. Curto, Damiano G. Barone, Gabriele S. Kaminski Schierle, George G. Malliaras
    Journal Name: Advanced Functional Materials
    Publisher: Wiley
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1002/adfm.202417312
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    Citation Count: 0
  • A STING–CASM–GABARAP pathway activates LRRK2 at lysosomes
    2025
    OPEN
    Title: A STING–CASM–GABARAP pathway activates LRRK2 at lysosomes
    Author(s): Amanda Bentley‐DeSousa, Agnes Roczniak-Ferguson, Shawn M. Ferguson
    Journal Name: Journal of Cell Biology
    Publisher: Rockefeller University Press
    Vol: 224
    Issue #: 2
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1083/jcb.202310150
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    Citation Count: 0
  • Longitudinal qualitative assessment of meaningful symptoms and relevance of WATCH-PD digital measures for people with early Parkinson’s
    2025
    OPEN
    Title: Longitudinal qualitative assessment of meaningful symptoms and relevance of WATCH-PD digital measures for people with early Parkinson’s
    Author(s): Jennifer R. Mammen, Aaron B. Lerner, Raunak Al‐Rubayie, Melissa Kostrzebski, Diane Stephenson, Yuge Xiao, Carol Redmond, Mirinda Tyo, V Reddy, Peggy Auinger, E. Ray Dorsey, Jamie L. Adams
    Journal Name: Journal of Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 272
    Issue #: 2
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00415-024-12789-0
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    Citation Count: 0
  • Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation
    2025
    OPEN
    Title: Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation
    Author(s): Liqiang Chen, Hiba Douja Chehade, Hong‐Yuan Chu
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00867-z
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    Citation Count: 0
  • Passive Monitoring of Parkinson Tremor in Daily Life: A Prototypical Network Approach
    2025
    OPEN
    Title: Passive Monitoring of Parkinson Tremor in Daily Life: A Prototypical Network Approach
    Author(s): Luc J. W. Evers, Yordan P. Raykov, Tom Heskes, Jesse H. Krijthe, Bastiaan R. Bloem, Max A. Little
    Journal Name: Sensors
    Publisher: MDPI AG
    Vol: 25
    Issue #: 2
    Start Page: 366
    End Page: 366
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/s25020366
    Best OA location URL:
    Citation Count: 0
  • Use of Robust Norming to Create a Sensitive Cognitive Summary Score in De Novo Parkinson's Disease: An Illustrative Example
    2025
    OPEN
    Title: Use of Robust Norming to Create a Sensitive Cognitive Summary Score in De Novo Parkinson's Disease: An Illustrative Example
    Author(s): Daniel Weintraub, Michael C. Brumm, Ryan Kurth, Michele K. York
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mds.30111
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    Citation Count: 0
  • N2GNet tracks gait performance from subthalamic neural signals in Parkinson’s disease
    2025
    OPEN
    Title: N2GNet tracks gait performance from subthalamic neural signals in Parkinson’s disease
    Author(s): Jin Woo Choi, Chuyi Cui, Kevin B. Wilkins, Helen Brontë‐Stewart
    Journal Name: npj Digital Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41746-024-01364-6
    Best OA location URL:
    Citation Count: 0
  • Comprehensive characterization of the transcriptional landscape in Alzheimer’s disease (AD) brains
    2025
    OPEN
    Title: Comprehensive characterization of the transcriptional landscape in Alzheimer’s disease (AD) brains
    Author(s): Chengxuan Chen, Zhao Zhang, Yuan Liu, Wei Hong, Hande Karahan, Jun Wang, Wenbo Li, Lixia Diao, Meichen Yu, Andrew J. Saykin, Kwangsik Nho, Jungsu Kim, Leng Han
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.adn1927
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    Citation Count: 0
  • Fox Insight: Most Bothersome Symptoms in Early‐Stage Parkinson's Disease
    2025
    OPEN
    Title: Fox Insight: Most Bothersome Symptoms in Early‐Stage Parkinson's Disease
    Author(s): Aaron B. Lerner, Jennifer R. Mammen, Mirinda Tyo, Peggy Auinger, Raunak Al‐Rubayie, Yuge Xiao, Connie Marras, Jamie L. Adams
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mdc3.14321
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    Citation Count: 0
  • Neurophysiological gradient in the Parkinsonian subthalamic nucleus as a marker for motor symptoms and apathy
    2025
    OPEN
    Title: Neurophysiological gradient in the Parkinsonian subthalamic nucleus as a marker for motor symptoms and apathy
    Author(s): Elena Bernasconi, Deborah Amstutz, Alberto Averna, Petra Fischer, Mário Sousa, Ines Debove, Katrin Petermann, Laura Alva, Andreia D. Magalhães, M. Lenard Lachenmayer, T. A. Khoa Nguyen, Michaël Schüpbach, Andreas Nowacki, Claudio Pollo, Paul Krack, Gerd Tinkhauser
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00848-2
    Best OA location URL:
    Citation Count: 0
  • Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils
    2025
    OPEN
    Title: Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils
    Author(s): Lauren Fielding, Marissa Menard, Jürgen Roth, Maria Iuliano, Benjamin Dehay, Patricia Aguilar‐Calvo, Laura A. Volpicelli‐Daley
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 206
    Issue #:
    Start Page: 106820
    End Page: 106820
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.nbd.2025.106820
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    Citation Count: 0
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