551 - 575 of 6466 Results
Title
Year
- Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice2006OPENTitle: Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 103Issue #: 41Start Page: 15242End Page: 15247Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0602116103Best OA location URL: http://doi.org/10.1073/pnas.0602116103Citation Count: 139
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OPENTitle: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 47Start Page: 18754End Page: 18759Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0704908104Best OA location URL: http://doi.org/10.1073/pnas.0704908104Citation Count: 432
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OPENTitle: GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 105Issue #: 31Start Page: 10907End Page: 10912Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0802437105Best OA location URL: https://www.pnas.org/content/pnas/105/31/10907.full.pdfCitation Count: 268
- Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model2008OPENTitle: Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease modelJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 105Issue #: 2Start Page: 728End Page: 733Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0711018105Best OA location URL: http://doi.org/10.1073/pnas.0711018105Citation Count: 292
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OPENTitle: The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasisJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 105Issue #: 1Start Page: 145End Page: 150Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0710685105Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0710685105Citation Count: 540
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OPENTitle: Derivation of midbrain dopamine neurons from human embryonic stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 101Issue #: 34Start Page: 12543End Page: 12548Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0404700101Best OA location URL: http://doi.org/10.1073/pnas.0404700101Citation Count: 974
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OPENTitle: Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 33Start Page: 14063End Page: 14068Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0900096106Best OA location URL: http://doi.org/10.1073/pnas.0900096106Citation Count: 459
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OPENTitle: Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 7Start Page: 2429End Page: 2434Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0810996106Best OA location URL: http://doi.org/10.1073/pnas.0810996106Citation Count: 142
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OPENTitle: Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 29Start Page: 12175End Page: 12180Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0704091104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0704091104Citation Count: 343
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OPENTitle: Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 36Start Page: 15454End Page: 15459Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0813216106Best OA location URL: http://doi.org/10.1073/pnas.0813216106Citation Count: 265
- Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells2009OPENTitle: Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 18Start Page: 7613End Page: 7618Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0902396106Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2671325Citation Count: 231
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OPENTitle: In vivo demonstration that α-synuclein oligomers are toxicJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 10Start Page: 4194End Page: 4199Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1100976108Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976Citation Count: 1480
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OPENTitle: Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 109Issue #: 26Start Page: 10322End Page: 10327Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1203223109Best OA location URL: https://www.pnas.org/content/pnas/109/26/10322.full.pdfCitation Count: 98
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OPENTitle: Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 109Issue #: 39Start Page: 15918End Page: 15923Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1205102109Best OA location URL: https://www.pnas.org/content/pnas/109/39/15918.full.pdfCitation Count: 87
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 121
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 41Start Page: E3945End Page: 54Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/94836Citation Count: 211
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OPENTitle: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 27Start Page: 11441End Page: 11446Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0702717104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0702717104Citation Count: 537
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OPENTitle: R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 34Start Page: 14622End Page: 14627Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0906334106Best OA location URL: http://doi.org/10.1073/pnas.0906334106Citation Count: 309
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 1Start Page: E34End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 125
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 224
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OPENTitle: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 29Start Page: 10732End Page: 10737Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321785111Best OA location URL: https://www.pnas.org/content/pnas/111/29/10732.full.pdfCitation Count: 342
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OPENTitle: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 11Start Page: 4055End Page: 4060Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1323285111Best OA location URL: https://www.pnas.org/content/pnas/111/11/4055.full.pdfCitation Count: 116
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP12014OPENTitle: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 18Start Page: 6804End Page: 6809Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321845111Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/104291Citation Count: 213
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation2015OPENTitle: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 15Start Page: E1926End Page: 35Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417883112Best OA location URL: https://www.pnas.org/content/pnas/112/15/E1926.full.pdfCitation Count: 150
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo2015OPENTitle: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 49Start Page: E6818End Page: 24Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1519430112Best OA location URL: https://www.pnas.org/content/pnas/112/49/E6818.full.pdfCitation Count: 30