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  • LRRK2 variation and Parkinson's disease in African Americans
    2010
    OPEN
    Title: LRRK2 variation and Parkinson's disease in African Americans
    Author(s): Owen A. Ross, Greggory J. Wilhoite, Justin A. Bacon, Alexandra I. Soto‐Ortolaza, Jennifer M. Kachergus, Stephanie A. Cobb, Andreas Puschmann, Carles Vilariño‐Güell, Matthew J. Farrer, Neill R. Graff‐Radford, James F. Meschia, Zbigniew K. Wszołek
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1973
    End Page: 1976
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23163
    Best OA location URL: https://europepmc.org/articles/pmc2939165?pdf=render
    Citation Count: 13
  • Calcium channel blocker use and risk of Parkinson's disease
    2010
    OPEN
    Title: Calcium channel blocker use and risk of Parkinson's disease
    Author(s): Kelly Claire Simon, Xiang Gao, Honglei Chen, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1818
    End Page: 1822
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23191
    Best OA location URL: https://europepmc.org/articles/pmc2939261?pdf=render
    Citation Count: 41
  • Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
    2010
    OPEN
    Title: Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
    Author(s): Heather L. Melrose, Justus C. Dächsel, Bahareh Behrouz, S. Lincoln, Mei Yue, Kelly M. Hinkle, Caroline Kent, Elena Korvatska, Julie P. Taylor, L.M. Witten, Yian Qi Liang, Joel E. Beevers, Mona Boules, Brittany N. Dugger, Vanida A. Serna, A. Gaukhman, Xin Yu, Monica Castanedes‐Casey, Adam Braithwaite, Sina Ogholikhan, Nanlong Yu, D.I. Bass, G. Tyndall, Daniela Berg, Dennis W. Dickson, Christopher Janus, Matthew J. Farrer
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 40
    Issue #: 3
    Start Page: 503
    End Page: 517
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.07.010
    Best OA location URL: https://europepmc.org/articles/pmc2955774?pdf=render
    Citation Count: 263
  • 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    2010
    OPEN
    Title: 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    Author(s): R. Jeremy Nichols, Nicolas Dzamko, Nicholas A. Morrice, David G. Campbell, Mária Deák, Alban Ordureau, Thomas Macartney, Youren Tong, Jie Shen, Alan R. Prescott, Dario R. Alessi
    Journal Name: Biochemical Journal
    Publisher: Portland Press Ltd.
    Vol: 430
    Issue #: 3
    Start Page: 393
    End Page: 404
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1042/bj20100483
    Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/393/878058/bj4300393.pdf
    Citation Count: 381
  • Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease
    2010
    OPEN
    Title: Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease
    Author(s): Carine Karachi, David Grabli, Frédéric Bernard, Dominique Tandé, Nicolas Wattiez, Hayat Belaïd, Éric Bardinet, Annick Prigent, Hans‐Peter Nothacker, Stéphane Hunot, Andréas Hartmann, Stéphane Lehéricy, Étienne C. Hirsch, Chantal François
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 120
    Issue #: 8
    Start Page: 2745
    End Page: 2754
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci42642
    Best OA location URL: http://www.jci.org/articles/view/42642/files/pdf
    Citation Count: 396
  • Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists
    2010
    OPEN
    Title: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists
    Author(s): Cara A. Mosley, Timothy M. Acker, Kasper B. Hansen, Praseeda Mullasseril, Karen T. Andersen, Phuong Thanh Le, Kimberly Vellano, Hans Bräuner‐Osborne, Dennis C. Liotta, Stephen F. Traynelis
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 53
    Issue #: 15
    Start Page: 5476
    End Page: 5490
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm100027p
    Best OA location URL: https://europepmc.org/articles/pmc2920070?pdf=render
    Citation Count: 84
  • Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations
    2010
    OPEN
    Title: Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations
    Author(s): Arianna Tucci, Abi Li, Susanne A. Schneider, Janice L. Holton, Robert M. Johnson, Desmond P. Kidd, Jeremy Chataway, Kailash P. Bhatia, Andrew J. Lees, John Hardy, Tamás Révész, Henry Houlden
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 33
    Issue #: 4
    Start Page: 814
    End Page: 823
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2010.05.009
    Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2010.05.009
    Citation Count: 205
  • Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)
    2010
    OPEN
    Title: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)
    Author(s): Darren W. Engers, Patrick R. Gentry, Richard D. Williams, Julie D. Bolinger, C. David Weaver, Usha N. Menon, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins
    Journal Name: Bioorganic & Medicinal Chemistry Letters
    Publisher: Elsevier BV
    Vol: 20
    Issue #: 17
    Start Page: 5175
    End Page: 5178
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007
    Best OA location URL: https://europepmc.org/articles/pmc2922490?pdf=render
    Citation Count: 28
  • Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
    2010
    OPEN
    Title: Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
    Author(s): Jonathan Wills, Jessica M. Jones, Thomas Haggerty, Valeriy Duka, Jeffrey N. Joyce, Anita Sidhu
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 225
    Issue #: 1
    Start Page: 210
    End Page: 218
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.06.017
    Best OA location URL: https://europepmc.org/articles/pmc2922478?pdf=render
    Citation Count: 182
  • Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors
    2010
    OPEN
    Title: Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors
    Author(s): Xiaomin Su, Adrian P. Kells, Ernesto A. Salegio, R. Mark Richardson, Piotr Hadaczek, Janine Beyer, John Bringas, Philip Pivirotto, John Forsayeth, Krystof S. Bankiewicz
    Journal Name: Molecular Therapy
    Publisher: Elsevier BV
    Vol: 18
    Issue #: 8
    Start Page: 1490
    End Page: 1495
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/mt.2010.114
    Best OA location URL: http://www.cell.com/article/S1525001616310991/pdf
    Citation Count: 78
  • Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease
    2010
    OPEN
    Title: Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease
    Author(s): Min Shi, Cyrus P. Zabetian, Aneeka M. Hancock, Carmen Ginghină, Zhen Hong, Dora Yearout, Kathryn A. Chung, Joseph F. Quinn, Elaine R. Peskind, Douglas Galasko, Joseph Jankovic, James B. Leverenz, Jing Zhang
    Journal Name: Neuroscience Letters
    Publisher: Elsevier BV
    Vol: 480
    Issue #: 1
    Start Page: 78
    End Page: 82
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neulet.2010.06.009
    Best OA location URL: https://europepmc.org/articles/pmc2943649?pdf=render
    Citation Count: 193
  • Standard guidelines for publication of deep brain stimulation studies in Parkinson's disease (Guide4DBS‐PD)
    2010
    OPEN
    Title: Standard guidelines for publication of deep brain stimulation studies in Parkinson's disease (Guide4DBS‐PD)
    Author(s): Jerrold L. Vitek, Kelly E. Lyons, Roy A.E. Bakay, Alim‐Louis Benabid, Günther Deuschl, Mark Hallett, Roger Kurlan, Joseph J. Pancrazio, Ali R. Rezai, Benjamin L. Walter, Anthony E. Lang
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 11
    Start Page: 1530
    End Page: 1537
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23151
    Best OA location URL: https://europepmc.org/articles/pmc4775095?pdf=render
    Citation Count: 25
  • Low‐dose bafilomycin attenuates neuronal cell death associated with autophagy‐lysosome pathway dysfunction
    2010
    OPEN
    Title: Low‐dose bafilomycin attenuates neuronal cell death associated with autophagy‐lysosome pathway dysfunction
    Author(s): Violetta N. Pivtoraiko, Adam J. Harrington, Burton J. Mader, Austin M. Luker, Guy A. Caldwell, Kim A. Caldwell, Kevin A. Roth, John J. Shacka
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 114
    Issue #: 4
    Start Page: 1193
    End Page: 1204
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2010.06838.x
    Best OA location URL: https://europepmc.org/articles/pmc2910188?pdf=render
    Citation Count: 74
  • Dystrophin-associated protein scaffolding in brain requires α-dystrobrevin
    2010
    OPEN
    Title: Dystrophin-associated protein scaffolding in brain requires α-dystrobrevin
    Author(s): April D. Bragg, Sonal S. Das, Stanley C. Froehner
    Journal Name: NeuroReport
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 21
    Issue #: 10
    Start Page: 695
    End Page: 699
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1097/wnr.0b013e32833b0a3b
    Best OA location URL: https://europepmc.org/articles/pmc2889226?pdf=render
    Citation Count: 14
  • Risk of sleep-disordered breathing in Parkinson's disease
    2010
    OPEN
    Title: Risk of sleep-disordered breathing in Parkinson's disease
    Author(s): Wattanachai Chotinaiwattarakul, Praveen Dayalu, Ronald D. Chervin, Roger L. Albin
    Journal Name: Sleep and Breathing
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 3
    Start Page: 471
    End Page: 478
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s11325-010-0362-3
    Best OA location URL: https://europepmc.org/articles/pmc2978748?pdf=render
    Citation Count: 43
  • Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
    2010
    OPEN
    Title: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
    Author(s): Youren Tong, Hiroo Yamaguchi, Emilie Giaime, Scott Boyle, Raphael Kopan, Raymond J. Kelleher, Jie Shen
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 107
    Issue #: 21
    Start Page: 9879
    End Page: 9884
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1004676107
    Best OA location URL: https://europepmc.org/articles/pmc2906862?pdf=render
    Citation Count: 475
  • Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s Disease
    2010
    OPEN
    Title: Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s Disease
    Author(s): M. Rafiuddin Ahmed, Amandine Berthet, Э.Р. Бычков, Grégory Porras, Qin Li, Bernard Bioulac, Yonatan T. Carl, Robert F. Margolskee, Seunghyi Kook, Incarnation Aubert, Sandra Doveró, Évelyne Doudnikoff, Vsevolod V. Gurevich, Eugenia V. Gurevich, Erwan Bézard
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 2
    Issue #: 28
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.3000664
    Best OA location URL: https://europepmc.org/articles/pmc2933751?pdf=render
    Citation Count: 135
  • Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
    2010
    OPEN
    Title: Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
    Author(s): Erik Kvam, Michael R. Sierks, Charles B. Shoemaker, Anne Messer
    Journal Name: Protein Engineering, Design and Selection
    Publisher: Oxford University Press (OUP)
    Vol: 23
    Issue #: 6
    Start Page: 489
    End Page: 498
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/protein/gzq022
    Best OA location URL: https://academic.oup.com/peds/article-pdf/23/6/489/17494272/gzq022.pdf
    Citation Count: 58
  • Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imaging
    2010
    OPEN
    Title: Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imaging
    Author(s): David E. Vaillancourt, Matthew B. Spraker, Janey Prodoehl, Xiaohong Joe Zhou, Deborah M. Little
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 33
    Issue #: 1
    Start Page: 35
    End Page: 42
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2010.02.006
    Best OA location URL: https://europepmc.org/articles/pmc2908724?pdf=render
    Citation Count: 55
  • Patient-specific analysis of the relationship between the volume of tissue activated during DBS and verbal fluency
    2010
    OPEN
    Title: Patient-specific analysis of the relationship between the volume of tissue activated during DBS and verbal fluency
    Author(s): Ania Mikos, Dawn Bowers, Angela M. Noecker, Cameron C. McIntyre, Michelle Won, Ashutosh Chaturvedi, Kelly D. Foote, Michael S. Okun
    Journal Name: NeuroImage
    Publisher: Elsevier BV
    Vol: 54
    Issue #:
    Start Page: S238
    End Page: S246
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuroimage.2010.03.068
    Best OA location URL: https://europepmc.org/articles/pmc2908727?pdf=render
    Citation Count: 107
  • Parkinson’s Psychosis
    2010
    OPEN
    Title: Parkinson’s Psychosis
    Author(s): Laura B. Zahodne, Hubert H. Fernandez
    Journal Name: Current Treatment Options in Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 3
    Start Page: 200
    End Page: 211
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s11940-010-0072-y
    Best OA location URL: https://europepmc.org/articles/pmc3045857?pdf=render
    Citation Count: 25
  • Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
    2010
    OPEN
    Title: Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
    Author(s): Thomas G. Beach, Charles H. Adler, Lucia I. Sue, Linda Vedders, Lih-Fen Lue, Charles L. White, Haru Akiyama, John N. Caviness, Holly A. Shill, Marwan N. Sabbagh, Douglas G. Walker
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 119
    Issue #: 6
    Start Page: 689
    End Page: 702
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00401-010-0664-3
    Best OA location URL: https://europepmc.org/articles/pmc2866090?pdf=render
    Citation Count: 795
  • High regulatability favors genetic selection in SLC18A2 , a vesicular monoamine transporter essential for life
    2010
    OPEN
    Title: High regulatability favors genetic selection in SLC18A2 , a vesicular monoamine transporter essential for life
    Author(s): Zhicheng Lin, Ying Zhao, Chee Yeun Chung, Yanhong Zhou, Nian Xiong, Charles E. Glatt, Ole Isacson
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Vol: 24
    Issue #: 7
    Start Page: 2191
    End Page: 2200
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1096/fj.09-140368
    Best OA location URL: https://europepmc.org/articles/pmc2887259
    Citation Count: 16
  • Incidental Lewy body disease: Clinical comparison to a control cohort
    2010
    OPEN
    Title: Incidental Lewy body disease: Clinical comparison to a control cohort
    Author(s): Charles H. Adler, Donald J. Connor, Joseph G. Hentz, Marwan N. Sabbagh, John N. Caviness, Holly A. Shill, Brie N. Noble, Thomas G. Beach
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 5
    Start Page: 642
    End Page: 646
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.22971
    Best OA location URL: https://europepmc.org/articles/pmc2935627?pdf=render
    Citation Count: 130
  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
    2010
    OPEN
    Title: Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
    Author(s): Vivianna M. Van Deerlin, Patrick Sleiman, Maria Martinez‐Lage, Alice Chen‐Plotkin, Li-San Wang, Neill R. Graff‐Radford, Dennis W. Dickson, Rosa Rademakers, Bradley F. Boeve, Murray Grossman, Steven E. Arnold, David Mann, Stuart Pickering‐Brown, Harro Seelaar, Peter Heutink, John C. van Swieten, Jill R. Murrell, Bernardino Ghetti, Salvatore Spina, Jordan Grafman, John R. Hodges, Maria Grazia Spillantini, Sid Gilman, Andrew P. Lieberman, Jeffrey Kaye, Randall L. Woltjer, Eileen H. Bigio, Marsel Mesulam, Safa Al‐Sarraj, Claire Troakes, Roger N. Rosenberg, Charles L. White, Isidró Ferrer, Albert Lladó, Manuela Neumann, Hans A. Kretzschmar, Christine M. Hulette, Kathleen A. Welsh‐Bohmer, Bruce L. Miller, Ainhoa Alzualde, Adolfo López de Munain, Ann C. McKee, Marla Gearing, Allan I. Levey, James J. Lah, John Hardy, Jonathan D. Rohrer, Tammaryn Lashley, Ian R. Mackenzie, Howard Feldman, Ronald L. Hamilton, Steven T. DeKosky, Julie van der Zee, Samir Kumar‐Singh, Christine Van Broeckhoven, Richard Mayeux, Jean Paul Vonsattel, Juan C. Troncoso, Jillian J. Kril, John B. Kwok, Glenda M. Halliday, Thomas D. Bird, Paul G. Ince, Pamela J. Shaw, Nigel J. Cairns, John C. Morris, Catriona McLean, Charles DeCarli, William G. Ellis, Stefanie H. Freeman, Matthew P. Frosch, John H. Growdon, Daniel P. Perl, Mary Sano, David A. Bennett, Julie A. Schneider, Thomas G. Beach, Eric M. Reiman, Bryan K. Woodruff, Jeffrey L. Cummings, Harry V. Vinters, Carol A. Miller, Helena C. Chui, Irina Alafuzoff, Päivi Hartikainen, Danielle Seilhean, Douglas Galasko, Eliezer Masliah, Carl W. Cotman, MJ Tuñón, Mònica Martínez, David G. Muñoz, Steven L. Carroll, Daniel Marson, Peter Riederer, Nenad Bogdanović, Daniela Berg, Hákon Hákonarson, John Q. Trojanowski, Virginia M.‐Y. Lee
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Vol: 42
    Issue #: 3
    Start Page: 234
    End Page: 239
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ng.536
    Best OA location URL: https://europepmc.org/articles/pmc2828525?pdf=render
    Citation Count: 542
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