1601 - 1625 of 6564 Results
Title
Year
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OPENTitle: Spatiotemporal Pattern of Striatal ERK1/2 Phosphorylation in a Rat Model of L-DOPA–Induced Dyskinesia and the Role of Dopamine D1 ReceptorsJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 62Issue #: 7Start Page: 800End Page: 810Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2006.11.032Best OA location URL: http://doi.org/10.1016/j.biopsych.2006.11.032Citation Count: 271
- Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)2010OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29
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OPENTitle: Efficient estimation of nonparametric genetic risk function with censored dataJournal Name: BiometrikaPublisher: Oxford University Press (OUP)Vol: 102Issue #: 3Start Page: 515End Page: 532Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/biomet/asv030Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4581539Citation Count: 7
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-leadJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 3Start Page: 962End Page: 966Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.11.104Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3787871Citation Count: 58
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OPENTitle: Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 17Start Page: 4967End Page: 4970Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2009.07.072Best OA location URL: http://doi.org/10.1016/j.bmcl.2009.07.072Citation Count: 38
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OPENTitle: Identifying blood-brain-barrier selective single-chain antibody fragmentsJournal Name: Biotechnology JournalPublisher: WileyVol: 9Issue #: 5Start Page: 664End Page: 674Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/biot.201300550Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4073886Citation Count: 23
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OPENTitle: Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutationsJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 35Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20150128Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/35/5/e00254/477473/bsr035e254.pdfCitation Count: 27
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OPENTitle: Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samplesJournal Name: Biotechnology ProgressPublisher: WileyVol: 29Issue #: 2Start Page: 463End Page: 471Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/btpr.1698Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3618510Citation Count: 24
- Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulator2011OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Citation Count: 18
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OPENTitle: Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGEJournal Name: BMC BioinformaticsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page: 475End Page: 475Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2105-7-475Best OA location URL: https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-475Citation Count: 38
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulatorsJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 18Issue #: 20Start Page: 5626End Page: 5630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.08.087Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3182458Citation Count: 59
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OPENTitle: Toxic Oligomeric Alpha-Synuclein Variants Present in Human Parkinson’s Disease Brains Are Differentially Generated in Mammalian Cell ModelsJournal Name: BiomoleculesPublisher: MDPI AGVol: 5Issue #: 3Start Page: 1634End Page: 1651Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/biom5031634Best OA location URL: http://hdl.handle.net/2286/R.I.43313Citation Count: 40
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OPENTitle: Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: http://doi.org/10.1016/j.bmcl.2016.05.029Citation Count: 5
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OPENTitle: GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 105Issue #: 31Start Page: 10907End Page: 10912Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0802437105Best OA location URL: https://www.pnas.org/content/pnas/105/31/10907.full.pdfCitation Count: 268
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OPENTitle: Validation of nigrostriatal positron emission tomography measures: Critical limitsJournal Name: Annals of NeurologyPublisher: WileyVol: 73Issue #: 3Start Page: 390End Page: 396Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.23798Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3631302Citation Count: 89
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OPENTitle: Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosisJournal Name: Annals of NeurologyPublisher: WileyVol: 64Issue #: 1Start Page: 60End Page: 70Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.21425Best OA location URL: http://doi.org/10.1002/ana.21425Citation Count: 779
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OPENTitle: Symptoms of rapid eye movement sleep behavior disorder are associated with cholinergic denervation in Parkinson diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 71Issue #: 4Start Page: 560End Page: 568Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22691Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22691Citation Count: 250
- Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaques2013OPENTitle: Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaquesJournal Name: Annals of NeurologyPublisher: WileyVol: 74Issue #: 4Start Page: 602End Page: 610Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.23939Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3800272Citation Count: 40
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OPENTitle: 18F‐flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter studyJournal Name: Annals of NeurologyPublisher: WileyVol: 82Issue #: 4Start Page: 622End Page: 634Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25060Best OA location URL: https://escholarship.org/uc/item/01j9450zCitation Count: 175
- Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, α -Synuclein Synthesis, Interleukin-1β Release, and Cholinergic Action.2013OPENTitle: Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, α -Synuclein Synthesis, Interleukin-1β Release, and Cholinergic Action.Journal Name: Anti-Inflammatory & Anti-Allergy Agents in Medicinal ChemistryPublisher: Bentham Science Publishers Ltd.Vol: 12Issue #: 2Start Page: 117End Page: 128Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.2174/1871523011312020003Citation Count: 28
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OPENTitle: N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouseJournal Name: Annals of NeurologyPublisher: WileyVol: 69Issue #: 3Start Page: 509End Page: 520Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22162Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22162Citation Count: 138
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OPENTitle: SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein LevelJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 67Issue #: 11Start Page: 1350End Page: 6Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2010.279Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3010848Citation Count: 178
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OPENTitle: Tau positron emission tomographic imaging in aging and early Alzheimer diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 79Issue #: 1Start Page: 110End Page: 119Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.24546Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.24546Citation Count: 1007
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OPENTitle: Solvent exposures and parkinson disease risk in twinsJournal Name: Annals of NeurologyPublisher: WileyVol: 71Issue #: 6Start Page: 776End Page: 784Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22629Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22629Citation Count: 183
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OPENTitle: Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-SynucleinJournal Name: Applied SciencesPublisher: MDPI AGVol: 4Issue #: 1Start Page: 66End Page: 78Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/app4010066Best OA location URL: https://www.mdpi.com/2076-3417/4/1/66/pdf?version=1395063831Citation Count: 56