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4301 - 4350 of 5832 Results
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  • OPEN
    Title: Progression of MDS‐UPDRS Scores Over Five Years in De Novo Parkinson Disease from the Parkinson's Progression Markers Initiative Cohort
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mdc3.12553
    Citation Count: 136
  • OPEN
    Title: Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
    Journal Name: Molecular Cell
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.molcel.2017.08.020
    Citation Count: 165
  • OPEN
    Title: Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.7554/elife.28377
    Citation Count: 88
  • OPEN
    Title: TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1713969114
    Citation Count: 98
  • OPEN
    Title: A Nigro−Vagal Pathway Controls Gastric Motility and Is Affected in a Rat Model of Parkinsonism
    Journal Name: Gastroenterology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1053/j.gastro.2017.08.069
    Citation Count: 97
  • OPEN
    Title: Parkinson's disease susceptibility variants and severity of Lewy body pathology
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.09.009
    Citation Count: 17
  • OPEN
    Title: Color discrimination errors associate with axial motor impairments in Parkinson's Disease
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mdc3.12527
    Citation Count: 6
  • OPEN
    Title: Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/science.aam9080
    Citation Count: 704
  • OPEN
    Title: Improved diagnosis of Parkinson's disease from a detailed olfactory phenotype
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.447
    Citation Count: 14
  • OPEN
    Title: MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson’s Disease Phenotype
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.7b00287
    Citation Count: 75
  • OPEN
    Title: Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI
    Journal Name: Nature Protocols
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nprot.2017.081
    Citation Count: 129
  • OPEN
    Title: Subthalamic neural entropy is a feature of freezing of gait in freely moving people with Parkinson's disease
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2017.09.002
    Citation Count: 75
  • OPEN
    Title: Engineered Axonal Tracts as “Living Electrodes” for Synaptic‐Based Modulation of Neural Circuitry
    Journal Name: Advanced Functional Materials
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific, author manuscript
    DOI - Digital Object Identifier: 10.1002/adfm.201701183
    Citation Count: 46
  • OPEN
    Title: Beyond L-DOPA: hope for Parkinson’s treatment and diagnosis
    Journal Name: EBioMedicine
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.ebiom.2017.09.009
    Citation Count: 0
  • OPEN
    Title: Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson’s disease
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0184117
    Citation Count: 14
  • OPEN
    Title: α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2017.05.014
    Citation Count: 142
  • OPEN
    Title: β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/science.aaf3934
    Citation Count: 367
  • OPEN
    Title: Clinicopathologic discrepancies in a population‐based incidence study of parkinsonism in olmsted county: 1991‐2010
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27125
    Citation Count: 23
  • OPEN
    Title: The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.27105
    Citation Count: 454
  • OPEN
    Title: Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-017-10501-z
    Citation Count: 94
  • OPEN
    Title: The Kinase Fyn As a Novel Intermediate in l-DOPA-Induced Dyskinesia in Parkinson’s Disease
    Journal Name: Molecular Neurobiology
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s12035-017-0748-3
    Citation Count: 17
  • OPEN
    Title: The LRR-Roc-COR module of theChlorobium tepidumRoco protein: crystallization and X-ray crystallographic analysis
    Journal Name: Acta Crystallographica Section F Structural Biology Communications
    Publisher: International Union of Crystallography (IUCr)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1107/s2053230x17011955
    Citation Count: 8
  • OPEN
    Title: Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2017.08.009
    Citation Count: 54
  • OPEN
    Title: Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-017-0935-1
    Citation Count: 82
  • OPEN
    Title: LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection
    Journal Name: Journal of Experimental Medicine
    Publisher: Rockefeller University Press
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1084/jem.20170014
    Citation Count: 133
  • OPEN
    Title: GBA mutations in Parkinson disease: earlier death but similar neuropathological features
    Journal Name: European Journal of Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ene.13395
    Citation Count: 28
  • OPEN
    Title: The facial morphology in Down syndrome: A 3D comparison of patients with and without obstructive sleep apnea
    Journal Name: American Journal of Medical Genetics Part A
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ajmg.a.38399
    Citation Count: 21
  • OPEN
    Title: Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays
    Journal Name: Journal of Visualized Experiments
    Publisher: MyJove Corporation
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3791/55361
    Citation Count: 7
  • OPEN
    Title: Cholinergic activity and levodopa‐induced dyskinesia: a multitracer molecular imaging study
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.438
    Citation Count: 17
  • OPEN
    Title: LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson’s disease
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddx320
    Citation Count: 84
  • OPEN
    Title: Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0181844
    Citation Count: 28
  • OPEN
    Title: Measures of impulsivity in Parkinson's disease decrease after DBS in the setting of stable dopamine therapy
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.08.006
    Citation Count: 24
  • OPEN
    Title: Beliefs About Use of Complementary Health Approaches for Parkinson's Disease
    Journal Name: Holistic Nursing Practice
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1097/hnp.0000000000000229
    Citation Count: 0
  • OPEN
    Title: Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
    Journal Name: The Lancet
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/s0140-6736(17)31585-4
    Citation Count: 641
  • OPEN
    Title: Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-017-07181-0
    Citation Count: 106
  • OPEN
    Title: BRAPH: A graph theory software for the analysis of brain connectivity
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0178798
    Citation Count: 206
  • OPEN
    Title: Establishing the role of rare coding variants in known Parkinson's disease risk loci
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2017.07.009
    Citation Count: 17
  • OPEN
    Title: mzStudio: A Dynamic Digital Canvas for User-Driven Interrogation of Mass Spectrometry Data
    Journal Name: Proteomes
    Publisher: MDPI AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/proteomes5030020
    Citation Count: 23
  • OPEN
    Title: Differential role of CSF fatty acid binding protein 3, α-synuclein, and Alzheimer’s disease core biomarkers in Lewy body disorders and Alzheimer’s dementia
    Journal Name: Alzheimer's Research & Therapy
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13195-017-0276-4
    Citation Count: 114
  • OPEN
    Title: Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis
    Journal Name: Clinical and Translational Science
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1111/cts.12492
    Citation Count: 42
  • OPEN
    Title: Parkinson disease–associatedLRRK2 G2019Stransgene disrupts marrow myelopoiesis and peripheral Th17 response
    Journal Name: Journal of Leukocyte Biology
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1189/jlb.1a0417-147rr
    Citation Count: 30
  • OPEN
    Title: Impact of Cost-Sharing Increases on Continuity of Specialty Drug Use: A Quasi-Experimental Study
    Journal Name: Health Services Research
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/1475-6773.12744
    Citation Count: 23
  • OPEN
    Title: Motor subtype changes in early Parkinson's disease
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.07.018
    Citation Count: 66
  • OPEN
    Title: Vagally mediated effects of brain stem dopamine on gastric tone and phasic contractions of the rat
    Journal Name: American Journal of Physiology-Gastrointestinal and Liver Physiology
    Publisher: American Physiological Society
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1152/ajpgi.00180.2017
    Citation Count: 20
  • OPEN
    Title: Evaluating community health workers' attributes, roles, and pathways of action in immigrant communities
    Journal Name: Preventive Medicine
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.ypmed.2017.07.020
    Citation Count: 39
  • OPEN
    Title: Mentally stimulating activities associate with better cognitive performance in Parkinson disease
    Journal Name: Journal of Neural Transmission
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00702-017-1761-4
    Citation Count: 6
  • OPEN
    Title: O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease
    Journal Name: Molecular Brain
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13041-017-0311-1
    Citation Count: 74
  • OPEN
    Title: Temporal Order of Alzheimer’s Disease-Related Cognitive Marker Changes in BLSA and WRAP Longitudinal Studies
    Journal Name: Journal of Alzheimer's Disease
    Publisher: SAGE Publications
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3233/jad-170448
    Citation Count: 19
  • OPEN
    Title: Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ng.3916
    Citation Count: 884
  • OPEN
    Title: Predictors of weight loss in early treated Parkinson’s disease from the NET-PD LS-1 cohort
    Journal Name: Journal of Neurology
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00415-017-8562-4
    Citation Count: 39
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