MJFF Publications

Abundant non-inclusion α-synuclein pathology in Lewy body-negative LRRK2-mutant cases

2025

OPEN

Title: Abundant non-inclusion α-synuclein pathology in Lewy body-negative LRRK2-mutant cases

Author(s): Nanna Møller Jensen, Zagorka Vitic, Mia R. Antorini, Tobias Bruun Viftrup, Laura Parkkinen, Poul Henning Jensen

Journal Name: Acta Neuropathologica

Publisher: Springer Science and Business Media LLC

Vol: 149

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-05-02

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00401-025-02871-w

Best OA location URL: https://doi.org/10.1007/s00401-025-02871-w

Citation Count: 0

Characterizing the expression profile of 3R tau pathology in Pick’s disease

2025

OPEN

Title: Characterizing the expression profile of 3R tau pathology in Pick’s disease

Author(s): Nicole Tamvaka, Alexandra I. Soto‐Beasley, Marios Gavrielatos, Michael G. Heckman, Yingxue Ren, Evan Udine, Zachary Quicksall, Delaney Liskey, Monica Castanedes‐Casey, Zbigniew K. Wszołek, Bradley F. Boeve, Keith A. Josephs, Caroline Graff, Marka van Blitterswijk, Melissa E. Murray, Shanu F. Roemer, Dennis W. Dickson, Owen A. Ross

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 11

Issue #: 18

Start Page:

End Page:

Publication Date: 2025-05-02

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.1126/sciadv.adt6105

Best OA location URL: https://doi.org/10.1126/sciadv.adt6105

Citation Count: 0

Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease

2025

OPEN

Title: Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease

Author(s): Elena Eubanks, Katelyn VanderSleen, Jiya Mody, Neha Patel, Benjamin N. Sacks, Mahsa Darestani Farahani, Jinying Wang, Jordan Elliott, Nora Jaber, Fulya Akçimen, Sara Bandrés‐Ciga, Fadel Helweh, Jun Liu, Sanjana Archakam, Robert Kimelman, B Sharma, Philip Socha, Ananya Guntur, Yiming Huang, Nagendran Ramalingam, Elyse Guadagno, Tim Bartels, Ulf Dettmer, M. Maral Mouradian, Amir Houshang Bahrami, Wei Dai, Jean Baum, Zheng Shi, John Hardy, Eleanna Kara

Journal Name: Cell Reports

Publisher: Elsevier BV

Vol: 44

Issue #: 5

Start Page: 115636

End Page: 115636

Publication Date: 2025-05-01

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1016/j.celrep.2025.115636

Best OA location URL: https://doi.org/10.1016/j.celrep.2025.115636

Citation Count: 0

Neuronal α‐Synuclein Disease Stage Progression over 5 Years

2025

OPEN

Title: Neuronal α‐Synuclein Disease Stage Progression over 5 Years

Author(s): Tanya Simuni, Caroline Gochanour, Anuprita R. Nair, Michael C. Brumm, Christopher S. Coffey, Kathleen L. Poston, Lana M. Chahine, Daniel Weintraub, Caroline M. Tanner, Paulina Gonzàlez‐Latapi, Catherine Kopil, Yuge Xiao, Sohini Chowdhury, Tien Dam, Gennaro Pagano, Diane Stephenson, Andrew Siderowf, Billy Dunn, Kenneth Marek

Journal Name: Movement Disorders

Publisher: Wiley

Vol:

Issue #:

Start Page:

End Page:

Publication Date: 2025-04-30

Open Access(OA) Status: OPEN

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DOI - Digital Object Identifier: 10.1002/mds.30191

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The role of alpha-synuclein in synucleinopathy: Impact on lipid regulation at mitochondria–ER membranes

2025

OPEN

Title: The role of alpha-synuclein in synucleinopathy: Impact on lipid regulation at mitochondria–ER membranes

Author(s): Peter A. Barbuti, Cristina Guardia‐Laguarta, Taekyung Yun, Zena K. Chatila, Xena Flowers, Calvin Y.H. Wong, Bruno F. R. Santos, Simone B. Larsen, James S. Lotti, Nobutaka Hattori, Elizabeth M. Bradshaw, Ulf Dettmer, Saranna Fanning, Vilas Menon, Hasini Reddy, Andrew F. Teich, Rejko Krueger, Estela Área-Gómez, Serge Przedborski

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-30

Open Access(OA) Status: OPEN

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DOI - Digital Object Identifier: 10.1038/s41531-025-00960-x

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Genome-Wide Association Study of Glucocerebrosidase Activity Modifiers

2025

OPEN

Title: Genome-Wide Association Study of Glucocerebrosidase Activity Modifiers

Author(s): Emma N. Somerville, Lynne Krohn, Konstantin Senkevich, Eric Yu, Jamil Ahmad, Farnaz Asayesh, Jennifer A. Ruskey, Dan Spiegelman, Stanley Fahn, Cheryl Waters, S. Pablo Sardi, Roy N. Alcalay, Ziv Gan‐Or

Journal Name: Molecular Neurobiology

Publisher: Springer Science and Business Media LLC

Vol:

Issue #:

Start Page:

End Page:

Publication Date: 2025-04-29

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s12035-025-04996-1

Best OA location URL: https://doi.org/10.1007/s12035-025-04996-1

Citation Count: 0

LRRK2 rare-variant per-domain genetic burden in Parkinson’s Disease: association confined to the kinase domain

2025

OPEN

Title: LRRK2 rare-variant per-domain genetic burden in Parkinson’s Disease: association confined to the kinase domain

Author(s): Sitki Cem Parlar, Konstantin Senkevich, Eric Yu, Jennifer A. Ruskey, Jamil Ahmad, Farnaz Asayesh, Dan Spiegelman, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Lior Greenbaum, Sharon Hassin‐Baer, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Roy N. Alcalay, Edward A. Fon, Jean‐François Trempe, Ziv Gan‐Or

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-29

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00934-z

Best OA location URL: https://doi.org/10.1038/s41531-025-00934-z

Citation Count: 0

Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease

2025

OPEN

Title: Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease

Author(s): Simon Ulvenes Kverneng, Kjersti Eline Stige, Haakon Berven, Sepideh Mostafavi, Katarina Lundervold, Michele Brischigliaro, Brage Brakedal, Geir Olve Skeie, Irene H. Flønes, Lilah Toker, Erika Fernández‐Vizarra, Ragnhild Skogseth, Kristoffer Haugarvoll, Yamila N. Torres Cleuren, Christian Dölle, Gonzalo S. Nido, Charalampos Tzoulis

Journal Name: Communications Medicine

Publisher: Springer Science and Business Media LLC

Vol: 5

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-27

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s43856-025-00817-7

Best OA location URL: https://doi.org/10.1038/s43856-025-00817-7

Citation Count: 0

Parkinson’s disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction

2025

OPEN

Title: Parkinson’s disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction

Author(s): Edward N. Wilson, Jacob Umans, Michelle S. Swarovski, Paras S. Minhas, Jaime Mendiola, Øivind Midttun, Arve Ulvik, Marian Shahid, Patricia Linortner, Siddhita D. Mhatre, Qian Wang, Divya Channappa, Nicole K. Corso, Lü Tian, Carolyn A. Fredericks, Geoffrey A. Kerchner, Edward D. Plowey, Brenna Cholerton, Per Magne Ueland, Cyrus P. Zabetian, Nora E. Gray, Joseph F. Quinn, Thomas J. Montine, Sharon J. Sha, Frank M. Longo, David A. Wolk, Alice Chen‐Plotkin, Victor W. Henderson, Tony Wyss‐Coray, Anthony D. Wagner, Elizabeth C. Mormino, Nima Aghaeepour, Kathleen L. Poston, Katrin I. Andreasson

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-26

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00964-7

Best OA location URL: https://doi.org/10.1038/s41531-025-00964-7

Citation Count: 0

Four questions to predict cognitive decline in de novo Parkinson’s disease

2025

OPEN

Title: Four questions to predict cognitive decline in de novo Parkinson’s disease

Author(s): Jan Hlavnička, Josef Mana, Ondřej Bezdíček, Martin Čihák, Filip Havlík, Dominik Škrabal, Tereza Bartošová, Karel Šonka, Evžen Růžička, Petr Dušek

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-25

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00958-5

Best OA location URL: https://doi.org/10.1038/s41531-025-00958-5

Citation Count: 0

IC100 blocks inflammasome activation induced by α-synuclein aggregates and ASC specks

2025

OPEN

Title: IC100 blocks inflammasome activation induced by α-synuclein aggregates and ASC specks

Author(s): Brianna Cyr, Regina Vontell, Roey Hadad, Juan Pablo de Rivero Vaccari, Robert W. Keane

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-25

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-025-00963-8

Best OA location URL: https://doi.org/10.1038/s41531-025-00963-8

Citation Count: 0

Development of a simplified smell test to identify Parkinson’s disease using multiple cohorts, machine learning and item response theory

2025

OPEN

Title: Development of a simplified smell test to identify Parkinson’s disease using multiple cohorts, machine learning and item response theory

Author(s): Juan Li, Kelsey F. Grimes, Joseph Saade, Julianna J. Tomlinson, Tiago Mestre, Sebastian Schade, Sandrina Weber, Mohammed Dakna, Tamara Wicke, Elisabeth Lang, Claudia Trenkwalder, Natalina Salmaso, Andrew Frank, Tim Ramsay, Douglas G. Manuel, Brit Mollenhauer, Michael G. Schlossmacher

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-23

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00904-5

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Citation Count: 0

Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection

2025

OPEN

Title: Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection

Author(s): Debotri Chatterjee, Drishya Kurup, Richard J. Smeyne

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-23

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-025-00925-0

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Liganded magnetic nanoparticles for magnetic resonance imaging of α-synuclein

2025

OPEN

Title: Liganded magnetic nanoparticles for magnetic resonance imaging of α-synuclein

Author(s): Hope Pan, Melinda Balbirnie, Ke Hou, Naomi S. Sta Maria, Shruti Sahay, Paul Denver, Stefano Lepore, Mychica Jones, Xiaohong Zuo, Chunni Zhu, Hilda Mirbaha, Hedieh Shahpasand‐Kroner, Marisa Mekkittikul, Jiahui Lu, Carolyn J. Hu, Xinyi Cheng, Romany Abskharon, M.R. Sawaya, Christopher Kazu Williams, Harry V. Vinters, Russell E. Jacobs, Neil Harris, Gregory M. Cole, Sally A. Frautschy, David Eisenberg

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-23

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00918-z

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LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons

2025

OPEN

Title: LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons

Author(s): Chuyu Chen, Meghan Masotti, Nathaniel Shepard, Vanessa Promes, Giulia Tombesi, Daniel Arango, Claudia Manzoni, Elisa Greggio, Sabine Hilfiker, Yevgenia Kozorovitskiy, Loukia Parisiadou

Journal Name: Molecular Psychiatry

Publisher: Springer Science and Business Media LLC

Vol:

Issue #:

Start Page:

End Page:

Publication Date: 2025-04-23

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41380-025-03030-z

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MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson’s HLA locus exhibits epigenetic regulation

2025

OPEN

Title: MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson’s HLA locus exhibits epigenetic regulation

Author(s): Elizabeth M. Kline, Janna Jernigan, Christopher D. Scharer, Jeffrey Maurer, Sakeenah L. Hicks, Mary K. Herrick, Rebecca L. Wallings, Sean D. Kelly, Jianjun Chang, Kelly B. Menees, Nikolaus R. McFarland, Jeremy M. Boss, Malú G. Tansey, Valerie Joers

Journal Name: Scientific Reports

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-21

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41598-025-95679-3

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Citation Count: 0

Neuroimaging-based data-driven subtypes of spatiotemporal atrophy due to Parkinson’s disease

2025

OPEN

Title: Neuroimaging-based data-driven subtypes of spatiotemporal atrophy due to Parkinson’s disease

Author(s): Zeena Shawa, Cameron Shand, Beatrice Taylor, Henk W. Berendse, Chris Vriend, Tim D. van Balkom, Odile A. van den Heuvel, Ysbrand D. van der Werf, Jiun‐Jie Wang, Chih‐Chien Tsai, Jason Druzgal, Benjamin T. Newman, Tracy R. Melzer, Toni L. Pitcher, John C. Dalrymple‐Alford, Tim Anderson, Gaëtan Garraux, Mario Rango, Petra Schwingenschuh, Melanie Suette, Laura M. Parkes, Sarah Al‐Bachari, Johannes Klein, Joshua Shulman, Corey T. McMillan, Fabrizio Piras, Daniela Vecchio, Clelia Pellicano, Chencheng Zhang, Kathleen L. Poston, Elnaz Ghasemi, Fernando Cendes, Clarissa Lin Yasuda, Duygu Tosun, Philip Mosley, Paul M. Thompson, Neda Jahanshad, Conor Owens‐Walton, Emile d’Angremont, Eva M. van Heese, Max A. Laansma, André Altmann, Max A. Laansma, Joanna K. Bright, Sarah Al‐Bachari, Tim Anderson, Tyler Ard, Francesca Assogna, Katherine Baquero, Henk W. Berendse, Beth Newman, Fernando Cendes, John C. Dalrymple‐Alford, Rob M.A. de Bie, Ines Debove, Michiel F. Dirkx, Jason Druzgal, Hedley Emsley, Gaëtan Garraux, Rachel Guimarães, Boris A. Gutman, Rick C. Helmich, Johannes Klein, Clare E. Mackay, Corey T. McMillan, Tracy R. Melzer, Laura M. Parkes, Fabrizio Piras, Toni L. Pitcher, Kathleen L. Poston, Mario Rango, Letícia Ribeiro, Cristiane S. Rocha, Christian Rummel, Lucas S. R. Santos, Reinhold Schmidt, Petra Schwingenschuh, Gianfranco Spalletta, Letizia Squarcina, Odile A. van den Heuvel, Chris Vriend, Jiun‐Jie Wang, Daniel Weintraub, Roland Wiest, Clarissa Lin Yasuda, Neda Jahanshad, Paul M. Thompson, Ysbrand D. van der Werf, Rimona S. Weil, Neil P. Oxtoby

Journal Name: Brain Communications

Publisher: Oxford University Press (OUP)

Vol: 7

Issue #: 2

Start Page:

End Page:

Publication Date: 2025-04-16

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1093/braincomms/fcaf146

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Citation Count: 0

Prioritizing Parkinson’s disease risk genes in genome-wide association loci

2025

OPEN

Title: Prioritizing Parkinson’s disease risk genes in genome-wide association loci

Author(s): Lara M. Lange, Catalina Cerquera Cleves, Marijn Schipper, Georgia Panagiotaropoulou, Alice Braun, Julia Kraft, Swapnil Awasthi, Nathaniel Bell, Daniëlle Posthuma, Stephan Ripke, Cornelis Blauwendraat, Karl Heilbron

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-16

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00933-0

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Citation Count: 0

Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson’s disease-like neurodegeneration

2025

OPEN

Title: Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson’s disease-like neurodegeneration

Author(s): Hélèna L. Denis, Aurélie de Rus Jacquet, Melanie Alpaugh, Michel Panisset, Roger A. Barker, Éric Boilard, Francesca Cicchetti

Journal Name: Fluids and Barriers of the CNS

Publisher: Springer Science and Business Media LLC

Vol: 22

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-14

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1186/s12987-025-00646-9

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Citation Count: 0

Additive effect of distant Lewy bodies and tau seeds injections on nigral degeneration in macaques

2025

OPEN

Title: Additive effect of distant Lewy bodies and tau seeds injections on nigral degeneration in macaques

Author(s): Morgane Darricau, Valentine Kulifaj, Marie-Laure Arotçarena, Qin Li, Panagiotis Katsinelos, William A. McEwan, Maria Xilouri, Benjamin Dehay, Erwan Bézard, Vincent Planche

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-13

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41531-025-00938-9

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Astrocytic RNA editing regulates the host immune response to alpha-synuclein

2025

OPEN

Title: Astrocytic RNA editing regulates the host immune response to alpha-synuclein

Author(s): Karishma D’Sa, Minee-Liane Choi, Aaron Z. Wagen, Núria Setó‐Salvia, Olga Kopach, James R. Evans, Margarida Rodrigues, Patricia Lopez-Garcia, Joanne Lachica, Benjamin Clarke, Jaijeet Singh, Ali Ghareeb, James Bayne, Melissa Grant‐Peters, Sonia García-Ruiz, Zhongbo Chen, Samuel G. Rodriques, Dilan Athauda, Emil K. Gustavsson, Sarah A. Gagliano Taliun, Christina E. Toomey, Regina H. Reynolds, George R. Young, Stephanie Strohbuecker, Thomas T. Warner, Dmitri A. Rusakov, Rickie Patani, Clare Bryant, David Klenerman, Sonia Gandhi, Mina Ryten

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 11

Issue #: 15

Start Page:

End Page:

Publication Date: 2025-04-11

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/sciadv.adp8504

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Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein

2025

OPEN

Title: Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein

Author(s): Maria Zacharopoulou, Neeleema Seetaloo, James F. Ross, Amberley D. Stephens, Giuliana Fusco, Thomas M. McCoy, Wenyue Dai, Ioanna Mela, Ana Fernández‐Villegas, Anne Martel, Alexander F. Routh, Alfonso De Simone, Jonathan J. Phillips, Gabriele S. Kaminski Schierle

Journal Name: Journal of the American Chemical Society

Publisher: American Chemical Society (ACS)

Vol: 147

Issue #: 16

Start Page:

End Page:

Publication Date: 2025-04-10

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1021/jacs.4c13473

Best OA location URL: https://doi.org/10.1021/jacs.4c13473

Citation Count: 0

Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

2025

OPEN

Title: Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

Author(s): Moriah R. Arnold, Gabriel Cohn, Kezia Catharina Oxe, Somarr N. Elliott, Cindy Moore, Allison May Zhou, Peter V. Laraia, Sahar Shekoohi, Dillon Brownell, Rosalie C. Sears, R. L. Woltjer, Charles K. Meshul, Stephan N. Witt, Dorthe Helena Larsen, Vivek K. Unni

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 11

Issue #: 15

Start Page:

End Page:

Publication Date: 2025-04-09

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/sciadv.adq2519

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GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau

2025

OPEN

Title: GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau

Author(s): Diana Acosta Ingram, Emir Turkes, Tae Yeon Kim, S.T. Vo, Nicholas Sweeney, Marie-Amandine Bonte, Ryan Rutherford, Dominic Julian, Meixia Pan, Jacob Marsh, Andrea R. Argouarch, Min Wu, Douglas W. Scharre, Erica H. Bell, Lawrence S. Honig, Jean Paul Vonsattel, Geidy E. Serrano, Thomas G. Beach, Celeste M. Karch, Aimee W. Kao, Mark E. Hester, Xianlin Han, Hongjun Fu

Journal Name: Nature Communications

Publisher: Springer Science and Business Media LLC

Vol: 16

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-09

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41467-025-58585-w

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Tet2 loss and enhanced ciliogenesis suppress α-synuclein pathology

2025

OPEN

Title: Tet2 loss and enhanced ciliogenesis suppress α-synuclein pathology

Author(s): Quansah Emmanuel, Naman Vatsa, Elizabeth Ensink, Jaycie Brown, Tyce Cave, Miguel Aguileta, Emily Schulz, Allison Lindquist, Carla Gilliland, Jennifer A. Steiner, Martha L. Escobar Galvis, Milda Milčiūtė, Michael X. Henderson, Patrik Brundin, Lena Brundin, Lee Marshall, Juozas Gordevičius

Journal Name: Acta Neuropathologica Communications

Publisher: Springer Science and Business Media LLC

Vol: 13

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-07

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1186/s40478-025-01988-z

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Application of new biologic disease criteria for synucleinopathies to the systemic synuclein sampling study cohort

2025

OPEN

Title: Application of new biologic disease criteria for synucleinopathies to the systemic synuclein sampling study cohort

Author(s): Lana M. Chahine, Michael C. Brumm, A R Nair, Sherri Mosovsky, Nicole K. Polinski, Thomas G. Beach, Brit Mollenhauer, Charles H. Adler

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-05

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00919-y

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Characterization of Isolated Human Astrocytes from Aging Brain

2025

OPEN

Title: Characterization of Isolated Human Astrocytes from Aging Brain

Author(s): Geidy E. Serrano, Sidra Aslam, Jessica E. Walker, Ignazio S. Piras, Matthew J. Huentelman, Richard Arce, Michael J. Glass, Anthony J. Intorcia, Katsuko E. Suszczewicz, Claryssa I. Borja, Madison P. Cline, Sanaria H. Qiji, Ileana Lorenzini, Suet Theng Beh, Monica Mariner, Addison Krupp, Rylee McHattie, Anissa Shull, Zekiel R. Wermager, Thomas G Beach

Journal Name: International Journal of Molecular Sciences

Publisher: MDPI AG

Vol: 26

Issue #: 7

Start Page: 3416

End Page: 3416

Publication Date: 2025-04-05

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3390/ijms26073416

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Hyposmia in Parkinson’s disease; exploring selective odour loss

2025

OPEN

Title: Hyposmia in Parkinson’s disease; exploring selective odour loss

Author(s): Eleanor Mitchell, Christian Mattjie, Jonathan P. Bestwick, Rodrigo C. Barros, Artur Francisco Schumacher Schuh, Cristina Simonet, Alastair Noyce

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-04

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-025-00922-3

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Seeding-competent early tau multimers are associated with cell type-specific transcriptional signatures

2025

OPEN

Title: Seeding-competent early tau multimers are associated with cell type-specific transcriptional signatures

Author(s): Rahel Feleke, Simona Jogaudaite, Elisavet Velentza‐Almpani, Leung Yeung-Yeung, Daniel Clode, Jeong Hun Ko, Ben Shin, S. Matthews, Maria Otero‐Jimenez, Marcelina J. Wojewska, Sandra Gray‐Rodriguez, Sarah J. Marzi, Maxwell P. Spires-Jones, Tara L. Spires‐Jones, Michael R. Johnson, Javier Alegre‐Abarrategui

Journal Name: Acta Neuropathologica

Publisher: Springer Science and Business Media LLC

Vol: 149

Issue #: 1

Start Page:

End Page:

Publication Date: 2025-04-04

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00401-025-02869-4

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Fears and uncertainties of people with Parkinson's disease

2025

OPEN

Title: Fears and uncertainties of people with Parkinson's disease

Author(s): Esme D. Trahair, Darby Steiger, Naomi Lowe, Robyn Rapoport, Caitlin Kelliher, Stephanie Benvengo, Catherine Kopil, Lana M. Chahine, Connie Marras, Sneha Mantri

Journal Name: Journal of Parkinson’s Disease

Publisher: SAGE Publications

Vol:

Issue #:

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Publication Date: 2025-04-03

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DOI - Digital Object Identifier: 10.1177/1877718x251328565

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Systematic review and consensus conceptual model of meaningful symptoms and functional impacts in early Parkinson’s Disease

2025

OPEN

Title: Systematic review and consensus conceptual model of meaningful symptoms and functional impacts in early Parkinson’s Disease

Author(s): Jennifer R. Mammen, Jamie Adams, Rikki Mangrum, Yuge Xiao, William Barbosa, Mirinda Tyo, Christopher Redmond, C. Carter, Kelly Cifelli, Robert Cifelli, Hope Maruzo, J. F. Meeker, Gerry Shultz, Charles R. Thomas, Claire Bale, Evan Davies, Catherine Kopil, Connie Marras, Tiago Mestre, Thomas Morel, Tanya Simuni, Glenn T. Stebbins, Daniel Weintraub, Diane Stephenson

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

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End Page:

Publication Date: 2025-04-03

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DOI - Digital Object Identifier: 10.1038/s41531-025-00907-2

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Genome‐wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease

2025

OPEN

Title: Genome‐wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease

Author(s): Xu Hou, Michael G. Heckman, Fabienne C. Fiesel, Shunsuke Koga, Alexandra I. Soto‐Beasley, Jens O. Watzlawik, Jing Zhao, Rebecca R. Valentino, Patrick W. Johnson, Launia J. White, Zachary Quicksall, Joseph S. Reddy, José Brás, Rita Guerreiro, Na Zhao, Guojun Bu, Dennis W. Dickson, Owen A. Ross, Wolfdieter Springer

Journal Name: Alzheimer's & Dementia

Publisher: Wiley

Vol: 21

Issue #: 4

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Publication Date: 2025-04-01

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DOI - Digital Object Identifier: 10.1002/alz.70198

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Sequential patterning of dynamic brain states distinguish Parkinson’s disease patients with mild cognitive impairments

2025

OPEN

Title: Sequential patterning of dynamic brain states distinguish Parkinson’s disease patients with mild cognitive impairments

Author(s): Aaron S. Kemp, Andrew J. Eubank, Yahya Younus, James E. Galvin, Fred Prior, Linda Larson‐Prior

Journal Name: NeuroImage: Clinical

Publisher: Elsevier BV

Vol: 46

Issue #:

Start Page: 103779

End Page: 103779

Publication Date: 2025-04-01

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DOI - Digital Object Identifier: 10.1016/j.nicl.2025.103779

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Sex- and region-dependent neuroinflammation in Alzheimer's disease.

2025

RESTRICTED

Title: Sex- and region-dependent neuroinflammation in Alzheimer's disease.

Author(s): Maricedes Acosta-Martínez, V. Carter, Aviram Nessim, Radha Panchal, Dalfino John, Jasbeer Dhawan, Thomas G. Beach, Geidy E. Serrano, Erin E. Sundermann, Anat Biegon

Journal Name: Alzheimer's & Dementia

Publisher: Wiley

Vol: 21

Issue #: 4

Start Page: e14603

End Page: e14603

Publication Date: 2025-04-01

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DOI - Digital Object Identifier: 10.1002/alz.14603

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Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia

2025

OPEN

Title: Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia

Author(s): Molly Memel, Adam M. Staffaroni, Ignacio Ilan‐Gala, J. García Castro, John Kornak, Carmela M. Tartaglia, Rowan Saloner, Anna M. VandeBunte, Emily W. Paolillo, Claire J. Cadwallader, Coty Chen, Maria Luisa Gorno‐Tempini, Malu Mandelli, Liana Apostolova, N. R. Graff-Radford, Irene Litvan, Ece Bayram, Peter Pressman, Toji Miyagawa, Ian R. Mackenzie, Jill Goldman, R. Ryan Darby, Brian S. Appleby, Len Petrucelli, Tania Gendron, Hilary W. Heuer, Leah K. Forseberg, Julio C. Rojas, Bradley F. Boeve, Nellie Brushaber, Kimiko Domoto‐Reilly, Nupur Ghoshal, Maria I. Lapid, Belén Pascual, Suzee Lee, Eliana Marisa Ramos, Vijay K. Ramanan, Rosa Rademakers, Katya Rascovsky, Alexander Pantelyat, Joseph C. Masdeu, Allison Snyder, Adam L. Boxer, Howard J. Rosen, Kaitlin B. Casaletto

Journal Name: Alzheimer's & Dementia

Publisher: Wiley

Vol: 21

Issue #: 4

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Publication Date: 2025-04-01

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DOI - Digital Object Identifier: 10.1002/alz.14630

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Cryo-TEM structure of β-glucocerebrosidase in complex with its transporter LIMP-2

2025

OPEN

Title: Cryo-TEM structure of β-glucocerebrosidase in complex with its transporter LIMP-2

Author(s): Jan Philipp Dobert, Jan-Hannes Schäfer, Thomas Dal Maso, P. N. Ravindran, Dustin J. E. Huard, Eileen Socher, Lisa A. Schildmeyer, Raquel L. Lieberman, Wim Versées, Arne Moeller, Friederike Zunke, Philipp Arnold

Journal Name: Nature Communications

Publisher: Springer Science and Business Media LLC

Vol: 16

Issue #: 1

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Publication Date: 2025-03-30

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DOI - Digital Object Identifier: 10.1038/s41467-025-58340-1

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An integrative network approach for longitudinal stratification in Parkinson’s disease

2025

OPEN

Title: An integrative network approach for longitudinal stratification in Parkinson’s disease

Author(s): Barry Ryan, Riccardo E. Marioni, T. Ian Simpson

Journal Name: PLOS Computational Biology

Publisher: Public Library of Science (PLoS)

Vol: 21

Issue #: 3

Start Page: e1012857

End Page: e1012857

Publication Date: 2025-03-28

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DOI - Digital Object Identifier: 10.1371/journal.pcbi.1012857

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Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer’s disease

2025

OPEN

Title: Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer’s disease

Author(s): Ching‐Chieh Chou, Ryan T. Vest, Miguel A. Prado, Joshua Wilson‐Grady, João A. Paulo, Yohei Shibuya, Patricia Moran‐Losada, Ting-Ting Lee, Jian Luo, Steven P. Gygi, Jeffery W. Kelly, Daniel Finley, Marius Wernig, Tony Wyss‐Coray, Judith Frydman

Journal Name: Nature Cell Biology

Publisher: Springer Science and Business Media LLC

Vol: 27

Issue #: 4

Start Page:

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Publication Date: 2025-03-26

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DOI - Digital Object Identifier: 10.1038/s41556-025-01623-y

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Association between serum sodium and sporadic Parkinson’s disease

2025

OPEN

Title: Association between serum sodium and sporadic Parkinson’s disease

Author(s): Wen Zhou, Qingqing Xia, Duan Liu, Junying Li, Liang Gong

Journal Name: Frontiers in Neuroscience

Publisher: Frontiers Media SA

Vol: 19

Issue #:

Start Page:

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Publication Date: 2025-03-25

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DOI - Digital Object Identifier: 10.3389/fnins.2025.1555831

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The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

2025

OPEN

Title: The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

Author(s): Lara M. Lange, Kristin Levine, Susan H. Fox, Connie Marras, Nazish Rafique, Nicole Kuznetsov, Dan Vitale, Hirotaka Iwaki, Katja Lohmann, Luca Marsili, Alberto J. Espay, Peter Bauer, Christian Beetz, Jessica Martin, Stewart A. Factor, Lenora A. Higginbotham, Honglei Chen, Hampton L. Leonard, Mike A. Nalls, Niccolò E. Mencacci, Huw R. Morris, Andrew Singleton, Christine Klein, Cornelis Blauwendraat, Zih‐Hua Fang, Emilia Gatto, Marcelo Kauffman, Samson Khachatryan, Zaruhi Tavadyan, Claire E. Shepherd, Julie Hunter, Kishore R. Kumar, Melina Ellis, Miguel E. Rentería, Sulev Kõks, Alexander Zimprich, Artur Francisco Schumacher Schuh, Carlos Roberto de Mello Rieder, Paula Saffie Awad, Vítor Tumas, Sarah Camargos, Edward A. Fon, Oury Monchi, Ted Fon, Benjamin Pizarro Galleguillos, Patricio Olguı́n, Marcelo Miranda, M. Leonor Bustamante, Pedro Chaná, Beisha Tang, Huifang Shang, Jifeng Guo, Piu Chan, Wei Luo, Gonzálo Arboleda, Jorge Orozco, Marlene Jiménez-Del-Río, Álvaro Hernández-Flores, Mohamed Salama, Walaa A. Kamel, Yared Z. Zewde, Alexis Brice, Jean‐Christophe Corvol, Ana Westenberger, Eva‐Juliane Vollstedt, Harutyun Madoev, Joanne Trinh, Johanna Junker, Anastasia Illarionova, Brit Mollenhauer, Franziska Hopfner, Günter U. Höglinger, Manu Sharma, Thomas Gasser, Sergiu Groppa, Albert Akpalu, Georgia Xiromerisiou, Georgios Hadjigorgiou, Efthymios Dadiotis, Ioannis E. Dagklis, Ioannis Tarnanas, Leonidas Stefanis, María Stamelou, Alex Medina, Germaine Hiu-Fai Chan, Nelson Yuk-Fai Cheung, Nancy Y. Ip, Phillip Chan, Xiaopu Zhou, Asha Kishore, Divya KP, Pramod Kr. Pal, Prashanth Lingappa Kukkle, Roopa Rajan, Rupam Borgohain, Mehri Salari, Andrea Quattrone, Monica Gagliardi, Enza Maria Valente, Micol Avenali, Grazia Annesi, Lucilla Parnetti, Tommaso Schirinzi, Manabu Funayama, Nobutaka Hattori, Tomotaka Shiraishi, Altynay Karimova, Gulnaz Kaishibayeva, Cholpon Shambetova, Rejko Krüger, Ai Huey Tan, Azlina Ahmad‐Annuar, Shen‐Yang Lim, Yi Wen Tay, Norlinah Mohamed Ibrahim, Nor Azian Abdul Murad, Shahrul Azmin, Wael Mohamed, Daniel Martínez-Ramírez, Mayela Rodríguez‐Violante, Paula Reyes‐Pérez, Bayasgalan Tserensodnom, Rajeev Ojha, Tim Anderson, Toni L. Pitcher, Arinola Sanyaolu, Njideka Okubadejo, Oluwadamilola O. Ojo, Jan Aasly, Lasse Pihlstrøm, Manuela Tan, Shoaib Ur-Rehman, Mario Cornejo‐Olivas, Maria Leila M. Doquenia, Raymond L. Rosales, Ángel Viñuela, Е. А. Яковенко, Bashayer Al Mubarak, Muhammad Umair, Eng‐King Tan, Jia Nee Foo, Ferzana Amod, Jonathan Carr, Soraya Bardien, Beomseok Jeon, Yun Joong Kim, Esther Cubo, Ignacio Álvarez, Janet Hoenicka, Katrin Beyer, María Teresa Periñán, Pau Pástor, Sarah El-Sadig, Kajsa Brolin, Christiane Zweier, Paul Krack, Gerd Tinkhauser, Chin‐Hsien Lin, Pin-Jui Kung, Hsiu-Chuan Wu, Ruey‐Meei Wu, Yih‐Ru Wu, Rim Amouri, Samia Ben Sassi, A. Nazlı Başak, Özgür Öztop Çakmak, Sibel Ertan, Gençer Genç, Alastair Noyce, Sumit Dey, Alejandro Martínez-Carrasco, Anette Schrag, Anthony H.V. Schapira, Eleanor J. Stafford, Henry Houlden, John Hardy, Kin Y. Mok, Mie Rizig, Nicholas Wood, Olaitan Okunoye, Rauan Kaiyrzhanov, Rimona S. Weil, Simona Jasaityte, Vida Obese, Camille Carroll, Claire Bale, Donald G. Grosset, Nigel Williams, Patrick A. Lewis, Seth Love, Simon Stott, Caroline B. Pantazis, Katherine M. Andersh, Laurel Screven, Sara Bandrés‐Ciga, Ignacio Juan Keller Sarmiento, Alyssa O’Grady, Bernadette Siddiqi, Bradford Casey, Brian Fiske, Charisse Comart, Justin Solle, Kaileigh Murphy, Maggie Kuhl, Naomi Louie, Sohini Chowdhury, Todd Sherer, Andrew K. Sobering, Cabell Jonas, Carlos Cruchaga, Laura Ibáñez, Claire Wegel, Tatiana Foroud, Deborah A. Hall, Dena G. Hernandez, Jonggeol Jeff Kim, Yeajin Song, Ejaz Shiamim, Ekemini Riley, Geidy E. Serrano, Ignácio F. Mata, Miguel Inca‐Martinez, Jared Williamson, Joseph Jankovic, Joshua Shulman, Kamalini Ghosh Galvelis, Karen Nuytemans, Karl Kieburtz, Katerina Markopoulou, Kenneth Marek, Lana M. Chahine, Lauren Ruffrage, Lisa Shulman, Marissa Dean, Matthew J. Farrer, Megan J. Puckelwartz, Steven Lubbe, Roger L. Albin, Roy N. Alcalay, Ruth Walker, Sonya B. Dumanis, Tao Xie, Thomas Beach, Faraz Faghri, Mary B. Makarious, Mathew J. Koretsky, Duan Nguyen, Toan Nguyen, Masharip Atadzhanov

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

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Publication Date: 2025-03-25

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DOI - Digital Object Identifier: 10.1038/s41531-025-00896-2

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Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner

2025

OPEN

Title: Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner

Author(s): Moriah R. Arnold, Suzie Chen, Vivek K. Unni

Journal Name: Frontiers in Oncology

Publisher: Frontiers Media SA

Vol: 15

Issue #:

Start Page:

End Page:

Publication Date: 2025-03-20

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DOI - Digital Object Identifier: 10.3389/fonc.2025.1554059

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Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo

2025

OPEN

Title: Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo

Author(s): Gerard Michael Coughlin, Máté Borsos, Bre’Anna H. Barcelona, Nathan Appling, Acacia M Hori, Elisha D.W. Mackey, Rana Eser, Cameron Jackson, Xinhong Chen, Sripriya Ravindra Kumar, Viviana Gradinaru

Journal Name: Nature Biotechnology

Publisher: Springer Science and Business Media LLC

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Publication Date: 2025-03-20

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DOI - Digital Object Identifier: 10.1038/s41587-025-02565-4

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The Exon-Based Transcriptomic Analysis of Parkinson’s Disease

2025

OPEN

Title: The Exon-Based Transcriptomic Analysis of Parkinson’s Disease

Author(s): Sulev Kõks

Journal Name: Biomolecules

Publisher: MDPI AG

Vol: 15

Issue #: 3

Start Page: 440

End Page: 440

Publication Date: 2025-03-19

Open Access(OA) Status: OPEN

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DOI - Digital Object Identifier: 10.3390/biom15030440

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PseudoSorter: A self-supervised spike sorting approach applied to reveal Tau-induced reductions in neuronal activity

2025

OPEN

Title: PseudoSorter: A self-supervised spike sorting approach applied to reveal Tau-induced reductions in neuronal activity

Author(s): Marius Brockhoff, Jakob Träuble, Sagnik Middya, Tanja Fuchsberger, Ana Fernández‐Villegas, Amberley D. Stephens, Miranda Robbins, Wenyue Dai, Belquis Haider, Sulay Vora, Nino F. Läubli, Clemens F. Kaminski, George G. Malliaras, Ole Paulsen, Gabriele S. Kaminski Schierle

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 11

Issue #: 11

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Publication Date: 2025-03-14

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DOI - Digital Object Identifier: 10.1126/sciadv.adr4155

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An axonal brake on striatal dopamine output by cholinergic interneurons

2025

OPEN

Title: An axonal brake on striatal dopamine output by cholinergic interneurons

Author(s): Yan-Feng Zhang, Pengwei Luan, Qinbo Qiao, Yiran He, Peter Zatka-Haas, Guofeng Zhang, Michael Z. Lin, Armin Lak, Miao Jing, Edward O. Mann, Stephanie J. Cragg

Journal Name: Nature Neuroscience

Publisher: Springer Science and Business Media LLC

Vol: 28

Issue #: 4

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Publication Date: 2025-03-13

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DOI - Digital Object Identifier: 10.1038/s41593-025-01906-5

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Structure–Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers

2025

OPEN

Title: Structure–Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers

Author(s): Jeffrey S. Stehouwer, Guofeng Huang, Dinahlee Saturnino Guarino, Manik L. Debnath, Ashok Polu, Steven J. Geib, Brian J. Lopresti, Miloš D. Ikonomović, N. Scott Mason, Robert H. Mach, Chester A. Mathis

Journal Name: Journal of Medicinal Chemistry

Publisher: American Chemical Society (ACS)

Vol: 68

Issue #: 6

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End Page:

Publication Date: 2025-03-11

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DOI - Digital Object Identifier: 10.1021/acs.jmedchem.4c02988

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Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F-4 for Tau Protein: A First-in-Human PET Study

2025

OPEN

Title: Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F-4 for Tau Protein: A First-in-Human PET Study

Author(s): Anton Lindberg, Junchao Tong, Chao Zheng, André Mueller, Heiko Kroth, Andrew Stephens, Chester A. Mathis, Neil Vasdev

Journal Name: ACS Chemical Neuroscience

Publisher: American Chemical Society (ACS)

Vol: 16

Issue #: 6

Start Page:

End Page:

Publication Date: 2025-03-10

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1021/acschemneuro.4c00866

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Microstructural Changes in Substantia Nigra Subfields Relate to Depression and Olfactory Impairments in Parkinson’s Disease Continuum; Insights from Diffusion Tensor Imaging

2025

RESTRICTED

Title: Microstructural Changes in Substantia Nigra Subfields Relate to Depression and Olfactory Impairments in Parkinson’s Disease Continuum; Insights from Diffusion Tensor Imaging

Author(s): Mehrdad Mozafar, Zobeydeh Dehghan Manshadi, Zohreh Molaei, Homayoon Babaei, Mohammad D. Mansouri, Sahba Shahbazi, Shayan Shakeri, Hanieh Mirhosseini, David Gulisashvili, Mahsa Mayeli

Journal Name: Clinical Neurology and Neurosurgery

Publisher: Elsevier BV

Vol: 251

Issue #:

Start Page: 108817

End Page: 108817

Publication Date: 2025-03-08

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DOI - Digital Object Identifier: 10.1016/j.clineuro.2025.108817

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Assessing DNA methylation detection for primary human tissue using nanopore sequencing

2025

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Title: Assessing DNA methylation detection for primary human tissue using nanopore sequencing

Author(s): Rylee Genner, Stuart Akeson, Melissa Meredith, Pilar Álvarez Jerez, Laksh Malik, Breeana Baker, Abigail Miano‐Burkhardt, Benedict Paten, Kimberley Billingsley, Cornelis Blauwendraat, Miten Jain

Journal Name: Genome Research

Publisher: Cold Spring Harbor Laboratory

Vol: 35

Issue #: 4

Start Page: gr.279159.124

End Page: gr.279159.124

Publication Date: 2025-03-07

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DOI - Digital Object Identifier: 10.1101/gr.279159.124

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LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization

2025

OPEN

Title: LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization

Author(s): Lana M. Chahine, David-Erick Lafontant, Seung Ho Choi, Hirotaka Iwaki, Cornelis Blauwendraat, Andrew Singleton, Michael C. Brumm, Roy N. Alcalay, Kalpana Merchant, Kelly Nudelman, Alain Dagher, Andrew Vo, Tao Qin, Charles S. Venuto, Karl Kieburtz, Kathleen L. Poston, Susan Bressman, Paulina González-Latapí, Brian Avants, Christopher S. Coffey, Danna Jennings, Eduardo Tolosa, Andrew Siderowf, Kenneth Marek, Tatyana Simuni, Kenneth Marek, Caroline M. Tanner, Tanya Simuni, Andrew Siderowf, Douglas Galasko, Lana M. Chahine, Christopher S. Coffey, Kalpana Merchant, Kathleen L. Poston, Roseanne D. Dobkin, Tatiana M. Foroud, Brit Mollenhauer, Dan Weintraub, Ethan G. Brown, Karl Kieburtz, Mark Frasier, Todd Sherer, Sohini Chowdhury, Roy N. Alcalay, Aleksandar Videnović, Duygu Tosun, Werner Poewe, Susan Bressman, Jan Hammer, Raymond James, Ekemini Riley, John Seibyl, Yi‐Ju Li, David G. Standaert, Sneha Mantri, Nabila Dahodwala, Michael A. Schwarzschild, Connie Marras, Hubert Fernandez, Ira Shoulson, Helen M. Rowbotham, Paola Casalin, Claudia Trenkwalder, Jamie L. Eberling, Katie Kopil, A. O'Grady, Maggie Kuhl, L. Kirsch, Tracy A. Willson, Emily Flagg, Bridget McMahon, Craig Stanley, Kim Fabrizio, Dixie Ecklund, Trevis Huff, Laura Heathers, Christopher Hobbick, Gena Antonopoulos, Chelsea Caspell‐Garcia, Michael C. Brumm, Arthur W. Toga, Karen Crawford, John E. Hamer, Doug Galasko, Andrew Singleton, Thomas J. Montine, Roseanne D. Dobkin, Monica Korell, Charles Adler, Amy W. Amara, Paolo Barone, Bastiaan R. Bloem, Kathrin Brockmann, Norbert Brüggemann, Kelvin L. Chou, Alberto J. Espay, Stewart A. Factor, Michelle Fullard, Robert Hauser, Penelope Hogarth, Shu-Ching Hu, Joshua Shulman, Stuart Isaacson, Christine Klein, Rejko Krueger, Mark Lew, Zoltan Mari, Maria José Martí, Nikolaus R. McFarland, Tiago Mestre, Emile Moukheiber, Alastair J. Noyce, Wolfgang H. Oertel, Njideka Okubadejo, Sarah A. O’Shea, Rajesh Pahwa, Nicola Pavese, Ron Postuma, Giulietta Riboldi, Lauren Ruffrage, Javier Ruiz‐Martínez, David A. Russell, Marie Saint‐Hilaire, Nancy Dos Santos, Wesley Schlett, Ruth B. Schneider, Holly Shill, David Shprecher, Leonidas Stefanis, Yen Tai, Arjun Tarakad, Eduardo Tolosa

Journal Name: Brain Communications

Publisher: Oxford University Press (OUP)

Vol: 7

Issue #: 2

Start Page:

End Page:

Publication Date: 2025-03-06

Open Access(OA) Status: OPEN

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DOI - Digital Object Identifier: 10.1093/braincomms/fcaf103

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