Title:A Smartphone Application as an Exploratory Endpoint in a Phase 3 Parkinson’s Disease Clinical Trial: A Pilot Study
Author(s):Alex Page, Norman C.W. Yung, Peggy Auinger, Charles S. Venuto, Alistair M. Glidden, Eric A. Macklin, Larsson Omberg, Michael A. Schwarzschild, E. Ray Dorsey
Title:New insights into the genetic etiology of Alzheimer’s disease and related dementias
Author(s):Céline Bellenguez, Fahri Küçükali, Iris E. Jansen, Luca Kleineidam, Sonia Moreno–Grau, Najaf Amin, Adam C. Naj, Rafael Campos-Martín, Benjamin Grenier‐Boley, Víctor Andrade, Peter Holmans, Anne Boland, Vincent Damotte, Sven J. van der Lee, Marcos R. Costa, Teemu Kuulasmaa, Qiong Yang, Itziar de Rojas, Joshua C. Bis, Amber Yaqub, Ivana Nedeljković, Julien Chapuis, Shahzad Ahmad, Vilmantas Giedraitis, Dag Aarsland, Pablo García‐González, Carla Abdelnour, Emilio Alarcón‐Martín, Daniel Alcolea, Montserrat Alegret, Ignacio Álvarez, Victoria Álvarez, Nicola J. Armstrong, Anthoula Tsolaki, Carmen Antúnez, Ildebrando Appollonio, Marina Arcaro, Silvana Archetti, Alfonso Arias Pastor, Beatrice Arosio, Lavinia Athanasiu, Henri Bailly, Nerisa Banaj, Miquel Baquero, Sandra Barral, Alexa Beiser, Ana Belén Pastor, Jennifer E. Below, Penelope Benchek, Luisa Benussi, Claudine Berr, Céline Besse, Valentina Bessi, Giuliano Binetti, Alessandra Bizarro, Rafael Blesa, Merçé Boada, Eric Boerwinkle, Barbara Borroni, Silvia Boschi, Paola Bossù, Geir Bråthen, Jan Bressler, Catherine Bresner, Henry Brodaty, Keeley J. Brookes, Luis Ignacio Brusco, Dolores Buiza‐Rueda, Katharina Bürger, Vanessa Burholt, William S. Bush, Miguel Calero, Laura B. Cantwell, Geneviève Chêne, Jaeyoon Chung, Michael L. Cuccaro, Ãngel Carracedo, Roberta Cecchetti, Laura Cervera‐Carles, Camille Charbonnier, Hung‐Hsin Chen, Caterina Chillotti, Simona Ciccone, Jurgen A.H.R. Claassen, Christopher Clark, Elisa Conti, Anaïs Corma‐Gómez, Emanuele Maria Costantini, Carlo Custodero, Delphine Daian, Carolina Dalmasso, Antonio Daniele, Efthimios Dardiotis, Jean‐François Dartigues, Peter Paul De Deyn, Kátia de Paiva Lopes, Lot D. de Witte, Stéphanie Debette, Jürgen Deckert, Teodoro del Ser, Nicola Denning, Anita L. DeStefano, Martin Dichgans, Janine Diehl‐Schmid, Mónica Díez-Fairén, Paolo Rossi, Srdjan Djurovic, Emmanuelle Duron, Emrah Düzel, Carole Dufouil, Gudny Eiriksdottir, Sebastiaan Engelborghs, Valentina Escott‐Price, Ana Espinosa, Michael Ewers, Kelley M. Faber, Fabrizio Tagliavini, Sune Fallgaard Nielsen, David W. Fardo, Lucia Farotti, Chiara Fenoglio, Marta Fernández‐Fuertes, Raffaele Ferrari, Catarina B. Ferreira, Evelyn Ferri, Bertrand Fin, Peter Fischer, Tormod Fladby, Klaus Fließbach, Bernard Fongang, Myriam Fornage, Juan Fortea, Tatiana M. Foroud, Silvia Fostinelli, Nick C. Fox, Emlio Franco-Macías, María J. Bullido, Ana Frank, Lutz Froelich, Brian Fulton‐Howard, Daniela Galimberti, José María García‐Alberca, Pablo García‐González, Sebastián García‐Madrona, Guillermo García‐Ribas, Roberta Ghidoni, Ina Giegling, Giaccone Giorgio, Alison Goate, Oliver Goldhardt, Duber Gomez-Fonseca, Antonio González‐Pérez, Caroline Graff, Giulia Grande, Emma Green, Timo Grimmer, Edna Grünblatt, Michelle Grunin, Vilmundur Guðnason, Tamar Guetta‐Baranes, Annakaisa Haapasalo, Georgios M. Hadjigeorgiou, Jonathan L. Haines, Kara L. Hamilton‐Nelson, Harald Hampel, Olivier Hanon, John Hardy, Annette M. Hartmann, Lucrezia Hausner, Janet Harwood, Stefanie Heilmann‐Heimbach, Seppo Helisalmi, Michael T. Heneka, Isabel Hernández, Martin J. Herrmann, Per Hoffmann, Clive Holmes, Henne Holstege, Raquel Huerto Vilas, Marc Hulsman, Jack Humphrey, Geert Jan Biessels, Xueqiu Jian, Charlotte Johansson, Gyungah Jun, Yuriko Kastumata, John Kauwe, Patrick G. Kehoe, Lena Kilander, Anne Kinhult Ståhlbom, Miia Kivipelto, Anne Koivisto, Johannes Kornhuber, Mary H. Kosmidis, Walter A. Kukull, Pavel P. Kuksa, Brian W. Kunkle, Amanda Kuzma, Carmen Lage, Erika J. Laukka, Lenore J. Launer, Alessandra Lauria, Chien‐Yueh Lee, Jenni Lehtisalo, Ondřej Lerch, Alberto Lleó, W.T. Longstreth, Oscar L. López, Adolfo López de Munain, Seth Love, Malin Löwemark, Lauren Luckcuck, Kathryn L. Lunetta, Yiyi Ma, Juan Macías, Catherine Macleod, Wolfgang Maier, Francesca Mangialasche, Marco Spallazzi, Marta Marquié, Iain Marshall, Eden R. Martin, Ángel Martín Montes, Carmen Martínez Rodríguez, Carlo Masullo, Richard Mayeux, Simon Mead, Patrizia Mecocci, Miguel Medina, Alun Meggy, Shima Mehrabian, Silvia Mendoza, Manuel Menéndez‐González, Pablo Mir, Susanne Moebus, Merel O. Mol, Laura Molina‐Porcel, Laura Montrreal, Laura Morelli, Fermín Moreno, Kevin Morgan, Thomas Mosley, Markus M. Nöthen, Carolina Muchnik, Shubhabrata Mukherjee, Benedetta Nacmias, Tiia Ngandu, Gaël Nicolas, Børge G. Nordestgaard, Robert Olaso, Adelina Orellana, Michela Orsini, Gemma Ortega, Alessandro Padovani, Paolo Caffarra, Goran Papenberg, Lucilla Parnetti, Florence Pasquier, Pau Pástor, Gina M. Peloso, Alba Pérez‐Cordón, Jordi Pérez‐Tur, Pierre Péricard, Oliver Peters, Yolande A.L. Pijnenburg, Juan A. Pineda, Gerard Piñol-Ripoll, Claudia Pisanu, Thomas Polak, Julius Popp, Daniëlle Posthuma, Josef Priller, Raquel Puerta, Olivier Quenez, Inés Quintela, Jesper Qvist Thomassen, Alberto Rábano, Innocenzo Rainero, Farid Rajabli, Inez Ramakers, Luís Miguel Real, Marcel Reinders, Christiane Reitz, Dolly Reyes‐Dumeyer, Perry Ridge, Steffi G. Riedel‐Heller, Peter Riederer, Natalia Roberto, Eloy Rodríguez‐Rodríguez, Arvid Rongve, Irene Rosas Allende, Maitée Rosende-Roca, José Luís Royo, Elisa Rubino, Dan Rujescu, María Eugenia Sáez, Paraskevi Sakka, Ingvild Saltvedt, Ángela Sanabria, María Bernal Sánchez‐Arjona, Florentino Sánchez-García, Pascual Sánchez‐Juan, Raquel Sánchez‐Valle, Sigrid B. Sando, Chloé Sarnowski, Claudia L. Satizábal, Michela Scamosci, Nikolaos Scarmeas, Elio Scarpini, Philip Scheltens, Norbert Scherbaum, Martin Scherer, Matthias Schmid, Anja Schneider, Jonathan M. Schott, Geir Selbæk, Davide Seripa, Manuel Serrano‐Ríos, Jin Sha, Alexey Shadrin, Olivia Anna Skrobot, Susan Slifer, Gijsje J. L. Snijders, Hilkka Soininen, Vincenzo Solfrizzi, Alina Solomon, Yeunjoo E. Song, Sandro Sorbi, Óscar Sotolongo‐Grau, Gianfranco Spalletta, Annika Spottke, Alessio Squassina, Eystein Stordal, Juan Pablo Tartan, Lluís Tárraga, Niccoló Tesi, Anbupalam Thalamuthu, Thomas Tegos, Giuseppe Tosto, Latchezar Traykov, Lucio Tremolizzo, Anne Tybjærg-Hansen, André G. Uitterlinden, Abbe Ullgren, Ingun Ulstein, Sergi Valero, Otto Valladares, Christine Van Broeckhoven, Jeffery M. Vance, Badri N. Vardarajan, Aad van der Lugt, Jasper Van Dongen, Jeroen van Rooij, John C. van Swieten, Rik Vandenberghe, Frans Verhey, Jean‐Sébastien Vidal, Jonathan Vogelgsang, Martin Vyhnálek, Michael Wagner, David Wallon, Li-San Wang, Ruiqi Wang, Leonie Weinhold, Jens Wiltfang, Gill Windle, Bob Woods, Mary Yannakoulia, Habil Zare, Yi Zhao, Xiaoling Zhang, Congcong Zhu, Miren Zulaica, EADB, Jan Laczó, Václav Maťoška, María Serpente, Francesca Assogna, Fabrizio Piras, Federica Piras, Valentina Ciullo, Jacob Shofany, Carlo Ferrarese, Simona Andreoni, Gessica Sala, Chiara Paola Zoia, Maria Del Zompo, Alberto Benussi, Patrizia Bastiani, Mari Takalo, Teemu Natunen, Tiina Laatikainen, Jaakko Tuomilehto, Riitta Antikainen, Timo Strandberg, Jaana Lindström, Markku Peltonen, Richard Abraham, Ammar Al‐Chalabi, Nicholas J. Bass, Carol Brayne, Kristelle S. Brown, John Collinge, David Craig, Pangiotis Deloukas, Nick C. Fox, Amy Gerrish, Michael Gill, Rhian Gwilliam, Denise Harold, Paul Hollingworth, Jarret A. Johnston, Lesley Jones, Brian Lawlor, Gill Livingston, Simon Lovestone, Michelle K. Lupton, Aoibhinn Lynch, David Mann, Bernadette McGuinness, Andrew McQuillin, Michael O‘Donovan, Michael J. Owen, Peter Passmore, John Powell, Petra Proitsi, Martin Rossor, Christopher E. Shaw, A. David Smith, H. Gurling, Stephen Todd, Catherine J. Mummery, Nathalie Ryan, Giordano Lacidogna, Ad Adarmes-Gómez, Ana Mauleón, Ana Pancho, A. Gailhajenet, Asunción Lafuente, Daniel Macías‐García, Elvira Martín, Esther Pelejà, F. Carrillo, Isabel Sastre Merlín, L. Garrote-Espina, Liliana Vargas, Mario Carrión‐Claro, M. Marín, Ma Labrador, Mar Buendía, M. D. Alonso, Marina Guitart, Mariona Moreno, Marta Ibarria, Mt Periñán, Núria Aguilera, Pilar Gómez‐Garre, Pilar Cañabate, R. Escuela, Rocío Pineda-Sánchez, R. Vigo-Ortega, Silvia Jesús, Sílvia Preckler, Silvia Rodrigo‐Herrero, Susana Diego, Alessandro Vacca, Fausto Roveta, Nicola Salvadori, Elena Chipi, Henning Boecker, Christoph Laske, Robert Perneczky, Costas A. Anastasiou, Daniel Janowitz, Rainer Malik, Anna Anastasiou, Kayenat Parveen, Carmen Lage, Sara López‐García, Anna Antonell, Kalina Mihova, Diyana Belezhanska, Heike Weber, Silvia Kochen, Patricia Solís, Nancy Medel, Julieta Lisso, Zulma Sevillano, Daniel G. Politis, Valeria Cores, Carolina Cuesta, Cecilia Ortiz, Juan Ignacio Bacha, Mario Rios, Aldo Saenz, Mariana Sanchez Abalos, Eduardo Köhler, Dana Lis Palacio, Ignacio Etchepareborda, Matias Köhler, Gisela V. Novack, Federico Ariel Prestia, Pablo Galeano, Eduardo M. Castaño, Sandra Germani, Carlos Reyes Toso, Matias Rojo, Carlos A. Ingino, Carlos Mangone, David C. Rubinsztein, Stefan Teipel, Nathalie Fiévet, Vincent Deramerourt, Charlotte Forsell, Håkan Thonberg, Maria Bjerke, Ellen De Roeck, Nicholas G. Martin, Natividad Olivar, GR@ACE, Núria Aguilera, Amanda Cano, Pilar Cañabate, Juan Macías, Olalla Maroñas, Raúl Núñez‐Llaves, Clàudia Olivé, E. Pelejà, DEGESCO, Astrid D. Adarmes-Gómez, M. D. Alonso, Guillermo Amer-Ferrer, Martirio Antequera, J A Burguera, Fátima Carrillo, Mario Carrión‐Claro, M. J. Casajeros, Marian M. de Pancorbo, R. Escuela, L. Garrote-Espina, Pilar Gómez‐Garre, S. Hevilla, Silvia Jesús, M. A. Labrador Espinosa, Agustina Legaz, Sara López‐García, Daniel Macías‐García, Salvadora Manzanares, Marta Marín‐Oto, Juan Marín-Muñoz, Tamara Marín, Begoña Martínez, Victoriana Martínez, Pablo Martínez-Lage Álvarez, Maite Mendioroz Iriarte, María Teresa Periñán-Tocino, Rocío Pineda-Sánchez, Diego Real de Asúa, Silvia Rodrigo, I. Sastre, M.P. Vicente, R. Vigo-Ortega, Liliana Vivancos, EADI, Jacques Epelbaum, Didier Hannequin, Dominique Campion, Vincent Deramecourt, Christophe Tzourio, Alexis Brice, Bruno Dubois, GERAD, Amy L. Williams, Charlene Thomas, Chloe Davies, Will Nash, Kimberley Dowzell, Atahualpa Castillo-Morales, Mateus Bernardo-Harrington, James Turton, Jenny Lord, Kristelle S. Brown, Emma Vardy, Elizabeth Fisher, Jason D. Warren, Martin Rossor, Natalie S. Ryan, Rita Guerreiro, James Uphill, Nick Bass, Reinhard Heun, Heike Kölsch, Britta Schürmann, André Lacour, Christine Herold, Janet Johnston, Peter Passmore, John Powell, Yogen Patel, Angela Hodges, Tim Becker, Donald Warden, Gordon Wilcock, Robert Clarke, Panagiotis Deloukas, Yoav Ben‐Shlomo, Nigel M. Hooper, Stuart Pickering‐Brown, Rebecca Sussams, Nick Warner, Anthony Bayer, Isabella Heuser, Dmitriy Drichel, Norman Klopp, Manuel Mayhaus, Matthias Riemenschneider, Sabrina Pinchler, Thomas Feulner, Wei Gu, Hendrik van den Bussche, Michael Hüll, Lutz Frölich, H-Erich Wichmann, Karl‐Heinz Jöckel, Michael O‘Donovan, Michael J. Owen, Demgene, Shahram Bahrami, Ingunn Bosnes, Per Selnes, Sverre Bergh, FinnGen, Aarno Palotie, Mark J. Daly, Howard J. Jacob, Athena Matakidou, Heiko Runz, Sally John, Robert M. Plenge, Mark McCarthy, Julie Hunkapiller, Meg Ehm, Dawn Waterworth, Caroline S. Fox, Anders Mälarstig, Kathy Klinger, Kathy Call, Timothy E.J. Behrens, Patrick Loerch, Tomi P. Mäkelä, Jaakko Kaprio, Petri Virolainen, Kari Pulkki, Terhi Kilpi, Markus Perola, Jukka Partanen, Anne Pitkäranta, Riitta Kaarteenaho, Seppo Vainio, Miia Turpeinen, Raisa Serpi, Tarja Laitinen, Johanna Mäkelä, Veli‐Matti Kosma, Urho M. Kujala, Outi Tuovila, Minna Hendolin, Raimo Pakkanen, Jeff Waring, Bridget Riley‐Gillis, Jimmy Liu, Shameek Biswas, Dorothée Diogo, Catherine Marshall, Xinli Hu, Matthias Gossel, Robert Graham, Beryl B. Cummings, Samuli Ripatti, Johanna Schleutker, Mikko Arvas, Olli Carpén, Reetta Hinttala, Johannes Kettunen, Arto Mannermaa, Jari Laukkanen, Valtteri Julkunen, Anne M. Remes, Reetta Kälviäinen, Jukka Peltola, Pentti Tienari, Juha O. Rinne, Adam Ziemann, Jeffrey F. Waring, Sahar Esmaeeli, Nizar Smaoui, Anne Lehtonen, Susan Eaton, Sanni Lahdenperä, Janet van Adelsberg, John A. Michon, Geoff Kerchner, Natalie Bowers, Edmond Teng, John D. Eicher, Vinay Mehta, Padhraig Gormley, Kari Linden, Christopher D. Whelan, Fanli Xu, David Pulford, Martti Färkkilâ, Sampsa Pikkarainen, Airi Jussila, Timo Blomster, Mikko Kiviniemi, Markku Voutilainen, Bob Georgantas, Graham Heap, Fedik Rahimov, Keith Usiskin, Tim Lu, Danny Oh, Kirsi Kalpala, Melissa Miller, Linda McCarthy, Kari K. Eklund, Antti Palomäki, Pia Isomäki, Laura Pirilä, Oili Kaipiainen‐Seppänen, Johanna Huhtakangas, Apinya Lertratanakul, Marla Hochfeld, Nan Bing, Jorge Esparza Gordillo, Nina Mars, Margit Pelkonen, Paula Kauppi, Hannu Kankaanranta, Terttu Harju, David A. Close, Steven M. Greenberg, Hubert Chen, Jo Betts, Soumitra Ghosh, Veikko Salomaa, Teemu Niiranen, Markus Juonala, Kaj Metsärinne, Mika Kähönen, Juhani Junttila, Markku Laakso, Jussi Pihlajamäki, Juha Sinisalo, Marja‐Riitta Taskinen, Tiinamaija Tuomi, Ben Challis, Andrew S. Peterson, Audrey Y. Chu, Jaakko Parkkinen, Anthony J. Muslin, Heikki Joensuu, Tuomo J Meretoja, Lauri A. Aaltonen, Johanna Mattson, Annika Auranen, Peeter Karihtala, Saila Kauppila, Päivi Auvinen, Klaus Elenius, Relja Popovic, Jennifer L. Schutzman, Andrey Loboda, Aparna Chhibber, Heli Lehtonen, Stefan McDonough, Marika Crohns, Diptee Kulkarni, Kai Kaarniranta, Joni A. Turunen, Terhi Ollila, Sanna Seitsonen, Hannu Uusitalo, Vesa Aaltonen, Hannele Uusitalo‐Järvinen, Marja Luodonpää, Nina Hautala, Stephanie Loomis, Erich C. Strauss, Hao Chen, Anna Podgornaia, Joshua Hoffman, Kaisa Tasanen, Laura Huilaja, Katariina Hannula‐Jouppi, Teea Salmi, Sirkku Peltonen, Leena Koulu, Ilkka T. Harvima, Ying Wu, David F. Choy, Pirkko J. Pussinen, Aino Salminen, Tuula Salo, David Rice, Pekka Nieminen, Ulla Palotie, Maria Siponen, Liisa Suominen, Päivi Mäntylä, Ulvi Kahraman Gürsoy, Vuokko Anttonen, Kirsi Sipilä, J. Wade Davis, Danjuma Quarless, Slavé Petrovski, Eleonor Wigmore, Chia-Yen Chen, Paola G. Bronson, Ellen Tsai, Yunfeng Huang, Joseph Maranville, Elmutaz Shaikho, Elhaj Mohammed, Samir Wadhawan, Erika Kvikstad, Minal Çalışkan, Diana Chang, Tushar Bhangale, Sarah A. Pendergrass, Emily Holzinger, Xing Chen, Åsa K. Hedman, Karen S. King, Clarence Wang, Ethan Xu, Franck Augé, Clément Chatelain, Deepak K. Rajpal, Dongyu Liu, Katherine M. Call, Tai-he Xia, Matt Brauer, Mitja Kurki, Juha Karjalainen, Aki S. Havulinna, Anu Jalanko, Priit Palta, Pietro Della Briotta Parolo, Wei Zhou, Susanna Lemmelä, Manuel A. Rivas, Jarmo Harju, Arto Lehistö, Andrea Ganna, Vincent Llorens, Hannele Laivuori, Sina Rüeger, Mari Niemi, Taru Tukiainen, Mary Pat Reeve, Henrike Heyne, Kimmo Palin, Javier Gracia‐Tabuenca, Harri Siirtola, Tuomo Kiiskinen, Jiwoo Lee, Kristin Tsuo, Amanda Elliott, Kati Kristiansson, Kati Hyvärinen, Jarmo Ritari, Miika Koskinen, Katri Pylkäs, Marita Kalaoja, Minna K. Karjalainen, Tuomo Mantere, Eeva Kangasniemi, Sami Heikkinen, Eija K. Laakkonen, Csilla Sipeky, Samuel Heron, Antti Karlsson, Dhanaprakash Jambulingam, Venkat Subramaniam Rathinakannan, Risto Kajanne, Mervi Aavikko, Manuel González Jiménez, Pietro della Briotta Parola, Arto Lehistö, Masahiro Kanai, Mari Kaunisto, Elina Kilpeläinen, Timo P. Sipilä, Georg Brein, Awaisa Ghazal, Anastasia Shcherban, Kati Donner, Anu Loukola, Päivi Laiho, Tuuli Sistonen, Essi Kaiharju, Markku Laukkanen, Elina Järvensivu, Sini Lähteenmäki, Lotta Männikkö, Regis Wong, Hannele Mattsson, Tero Hiekkalinna, Teemu Paajanen, Kalle Pärn, Javier Gracia‐Tabuenca, ADGC, Erin L. Abner, Perrie M. Adams, Alyssa Aguirre, Marilyn S. Albert, Roger L. Albin, Mariet Allen, Lisa Alvarez, Liana G. Apostolova, Steven E. Arnold, Sanjay Asthana, Craig Atwood, Gayle Ayres, Clinton T. Baldwin, Robert C. Barber, Lisa L. Barnes, Sandra Barral, Thomas G. Beach, James T. Becker, Gary W. Beecham, Duane Beekly, Jennifer E. Below, Penelope Benchek, Bruno A. Benítez, David Bennett, John Bertelson, Margaret E. Flanagan, Thomas D. Bird, Deborah Blacker, Bradley F. Boeve, James D. Bowen, Adam Boxer, James B. Brewer, James R. Burke, Jeffrey M. Burns, William S. Bush, Joseph D. Buxbaum, Nigel J. Cairns, Chuanhai Cao, Christopher S. Carlson, Cynthia M. Carlsson, Regina M. Carney, Minerva M. Carrasquillo, Scott Chasse, Marie‐Françoise Chesselet, Alessandra Chesi, Nathaniel A. Chin, Helena C. Chui, Jaeyoon Chung, Suzanne Craft, Paul K. Crane, David H. Cribbs, Elizabeth Crocco, Carlos Cruchaga, Michael L. Cuccaro, C. Munro Cullum, Eveleen Darby, Bárbara Davis, Philip L. De Jager, Charles DeCarli, John C. DeToledo, Malcolm Dick, Dennis W. Dickson, Beth A. Dombroski, Rachelle S. Doody, Ranjan Duara, Nilüfer Ertekin‐Taner, Denis A. Evans, Thomas Fairchild, Kenneth B. Fallon, Martin R. Farlow, John J. Farrell, Victoria Fernandez-Hernandez, Steven H. Ferris, Matthew P. Frosch, Brian Fulton‐Howard, Douglas R. Galasko, Adriana C. Gamboa, Marla Gearing, Daniel H. Geschwind, Bernardino Ghetti, John R. Gilbert, Thomas J. Grabowski, Neill R. Graff‐Radford, Struan F.A. Grant, Robert C. Green, John H. Growdon, Jonathan L. Haines, Håkon Håkonarson, James Hall, Ronald L. Hamilton, Oscar Harari, Lindy E. Harrell, Jacob Haut, Elizabeth Head, Victor W. Henderson, Michelle L. Hernandez, Timothy J. Hohman, Lawrence S. Honig, Ryan Huebinger, Matthew J. Huentelman, Christine M. Hulette, Bradley T. Hyman, Linda S. Hynan, Laura Ibáñez, Gail P. Jarvik, Suman Jayadev, Lee‐Way Jin, Kim G. Johnson, Leigh A. Johnson, M. Ilyas Kamboh, Anna M. Karydas, Mindy J. Katz, Jeffrey A. Kaye, C. Dirk Keene, Aisha Khaleeq, Ronald Kim, Janice Knebl, Neil W. Kowall, Joel H. Kramer, Pavel P. Kuksa, Frank M. LaFerla, James J. Lah, Eric B. Larson, Chien‐Yueh Lee, Edward B. Lee, Alan J. Lerner, Yuk Yee Leung, James B. Leverenz, Allan I. Levey, Mingyao Li, Andrew P. Lieberman, Richard B. Lipton, Mark Logue, Constantine G. Lyketsos, John Malamon, Douglas Mains, Daniel Marson, Frank Martiniuk, Deborah C. Mash, Eliezer Masliah, Paul J. Massman, Arjun V. Masurkar, Wayne C. McCormick, Susan M. McCurry, Andrew McDavid, Stefan McDonough, Ann C. McKee, Marsel Mesulam, Jesse Mez, Bruce L. Miller, Carol A. Miller, Joshua W. Miller, Thomas J. Montine, Edwin S. Monuki, John C. Morris, Amanda Myers, Trung Nguyen, Sid E. O’Bryant, John Olichney, Marcia G. Ory, Raymond F. Palmer, Joseph E. Parisi, Henry L. Paulson, Valory Pavlik, David Paydarfar, Victòria Aurora Ferrer Pérez, Elaine R. Peskind, Ronald C. Petersen, Jennifer E. Phillips‐Cremins, Aimee Pierce, Marsha J. Polk, Wayne W. Poon, Huntington Potter, Liming Qu, Mary Quiceno, Joseph F. Quinn, Ashok Raj, Murray A. Raskind, Eric M. Reiman, Barry Reisberg, Joan Reisch, John M. Ringman, Erik D. Roberson, Monica Rodriguear, Ekaterina Rogaeva, Howard J. Rosen, Roger N. Rosenberg, Donald R. Royall, Mark A. Sager, Mary Sano, Andrew J. Saykin, Julie A. Schneider, Lon S. Schneider, William W. Seeley, Susan H. Slifer, Scott A. Small, Amanda Smith, Janet P. Smith, Yeunjoo E. Song, Joshua A. Sonnen, Salvatore Spina, Peter St George‐Hyslop, Robert A. Stern, Alan Stevens, Stephen M. Strittmatter, David L. Sultzer, Russell H. Swerdlow, Rudolph E. Tanzi, Jeffrey L. Tilson, John Q. Trojanowski, Juan C. Troncoso, Debby W. Tsuang, Otto Valladares, Vivianna M. Van Deerlin, Linda J. Van Eldik, Robert Vassar, Harry V. Vinters, Jean‐Paul Vonsattel, Sandra Weıntraub, Kathleen A. Welsh‐Bohmer, Patrice L. Whitehead, Ellen M. Wijsman, Kirk C. Wilhelmsen, Benjamin Williams, Jennifer Williamson, Henrik Wilms, Thomas S. Wingo, Thomas Wısnıewskı, Randall L. Woltjer, Martin Woon, Clinton B. Wright, Chuang‐Kuo Wu, Steven G. Younkin, Chang‐En Yu, Lei Yu, Yuanchao Zhang, Yi Zhao, Xiongwei Zhu, CHARGE, Hieab H.H. Adams, Rufus Akinyemi, Muhammad Ali, Nicola J. Armstrong, Hugo J. Aparicio, Maryam Bahadori, James T. Becker, Monique M.B. Breteler, Daniel I. Chasman, Ganesh Chauhan, Hata Comic, Simon R. Cox, L. Adrienne Cupples, Gail Davies, Charles DeCarli, Marie-Gabrielle Duperron, Josée Dupuis, Tavia E. Evans, Frank Fan, Annette L. Fitzpatrick, Alison E. Fohner, Mary Ganguli, Mirjam I. Geerlings, Stephen J. Glatt, Héctor M. González, Monica Goss, Hans J. Grabe, Mohamad Habes, Susan R. Heckbert, Edith Hofer, Elliot Hong, Timothy M. Hughes, Tiffany F. Kautz, Maria J. Knol, William S. Kremen, Paul Lacaze, Jari Lahti, Quentin Le Grand, Elizabeth Litkowski, Shuo Li, Dan Liu, Xuan Liu, Marisa Loitfelder, Alisa K. Manning, Pauline Maillard, Riccardo E. Marioni, Bernard Mazoyer, Debora Melo van Lent, Hao Mei, Aniket Mishra, Paul Nyquist, Jeffrey R. O’Connell, Yash Patel, Tomáš Paus, Zdenka Pausová, Katri Raikkonen-Talvitie, Moeen Riaz, Stephen S. Rich, Jerome I. Rotter, José R. Romero, Gena Roshchupkin, Yasaman Saba, Muralidharan Sargurupremraj, Helena Schmidt, Reinhold Schmidt, Joshua Shulman, Jennifer A. Smith, Hema Sekhar, Reddy Rajula, Jean Shin, Jeannette Simino, Eeva Sliz, Alexander Teumer, Alvin G. Thomas, Adrienne Tin, Elliot M. Tucker–Drob, Dina Vojinović, Yanbing Wang, Galit Weinstein, Dylan M. Williams, Katharina Wittfeld, Lisa R. Yanek, Yunju Yang, Lindsay A. Farrer, Bruce M. Psaty, Mohsen Ghanbari, Towfique Raj, Perminder S. Sachdev, Karen A. Mather, Frank Jessen, M. Arfan Ikram, Alexandre de Mendonça, Jakub Hort, Magda Tsolaki, Margaret A. Pericak‐Vance, Philippe Amouyel, Julie Williams, Ruth Frikke‐Schmidt, Jordi Clarimón, Jean‐François Deleuze, Giacomina Rossi, Sudha Seshadri, Ole A. Andreassen, Martin Ingelsson, Mikko Hiltunen, Kristel Sleegers, Gerard D. Schellenberg, Cornelia M. van Duijn, Rebecca Sims, Wiesje M. van der Flier, Agustı́n Ruiz, Alfredo Ramı́rez, Jean‐Charles Lambert
Journal Name:Nature Genetics
Publisher:Springer Science and Business Media LLC
Vol:54
Issue #:4
Start Page:412
End Page:436
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by, cc-by
DOI - Digital Object Identifier:10.1038/s41588-022-01024-z
Title:African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1
Author(s):Pilar Álvarez Jerez, Peter Wild Crea, Daniel M. Ramos, Emil K. Gustavsson, Mandy Radefeldt, Andrey Damianov, Mary B. Makarious, Oluwadamilola O. Ojo, Kimberley J. Billingsley, Laksh Malik, Kensuke Daida, Sarah Bromberek, Fangle Hu, Zachary Schneider, Aditya Surapaneni, Julia T. Stadler, Mie Rizig, Huw R. Morris, Caroline B. Pantazis, Hampton L. Leonard, Laurel A. Screven, Yue Qi, Mike A. Nalls, Sara Bandrés‐Ciga, John Hardy, Henry Houlden, Celeste Eng, Esteban G. Burchard, Linda Kachuri, Chia-Ho Lin, Douglas L. Black, Global Parkinson’s Genetics Program (GP2), Mike A. Nalls, Andrew B. Singleton, Steffen Fischer, Peter Bauer, Xylena Reed, Mina Ryten, Christian Beetz, Michael E. Ward, Njideka Okubadejo, Cornelis Blauwendraat
Author(s):Mary B. Makarious, Hampton L. Leonard, Dan Vitale, Hirotaka Iwaki, Lana Sargent, Anant Dadu, Ivo Violich, Elizabeth Hutchins, David Saffo, Sara Bandres-Ciga, Jonggeol Jeff Kim, Yeajin Song, Melina Maleknia, Matt Bookman, Willy Nojopranoto, Roy H. Campbell, Sayed Hadi Hashemi, Juan A. Botia, John F. Carter, David W. Craig, Kendall Van Keuren-Jensen, Huw R. Morris, John A. Hardy, Cornelis Blauwendraat, Andrew B. Singleton, Faraz Faghri, Mike A. Nalls
Journal Name:npj Parkinson's Disease
Publisher:Springer Science and Business Media LLC
Vol:8
Issue #:1
Start Page:35
End Page:35
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by
DOI - Digital Object Identifier:10.1038/s41531-022-00288-w
Title:A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice
Author(s):Reem Abdel-Haq, Johannes C. M. Schlachetzki, Joseph C. Boktor, Thaisa M. Cantu-Jungles, Taren Thron, Mengying Zhang, John W. Bostick, Tahmineh Khazaei, Sujatha Chilakala, Lívia H. Morais, Greg Humphrey, Ali Keshavarzian, Jonathan E. Katz, Matthew Thomson, Rob Knight, Viviana Gradinaru, Bruce R. Hamaker, Christopher K. Glass, Sarkis K. Mazmanian
Journal Name:eLife
Publisher:eLife Sciences Publications, Ltd
Vol:11
Issue #:
Start Page:
End Page:
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by
DOI - Digital Object Identifier:10.7554/elife.81453
Title:Highly efficient generation of isogenic pluripotent stem cell models using prime editing
Author(s):Hanqin Li, Oriol Busquets, Yogendra Verma, Khaja Mohieddin Syed, Nitzan Kutnowski, Gabriella Pangilinan, Luke A. Gilbert, Helen S. Bateup, Donald C. Rio, Dirk Hockemeyer, Frank Soldner
Journal Name:eLife
Publisher:eLife Sciences Publications, Ltd
Vol:11
Issue #:
Start Page:
End Page:
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by
DOI - Digital Object Identifier:10.7554/elife.79208
Title:Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity
Author(s):Hilal A. Lashuel, Anne‐Laure Mahul‐Mellier, Salvatore Novello, Ramanath Narayana Hegde, Yllza Jasiqi, Melek Firat Altay, Sonia Donzelli, Sean M. DeGuire, Ritwik Burai, Pedro Magalhães, Anass Chiki, Jonathan Ricci, Manel Boussouf, Ahmed Sadek, Erik Stoops, Christian Iseli, Nicolas Guex
Journal Name:npj Parkinson's Disease
Publisher:Springer Science and Business Media LLC
Vol:8
Issue #:1
Start Page:136
End Page:136
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by
DOI - Digital Object Identifier:10.1038/s41531-022-00388-7
Title:Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons
Author(s):Mark van den Hurk, Shong Lau, Maria C. Marchetto, Jérôme Mertens, Shani Stern, Olga Corti, Alexis Brice, Beate Winner, Jürgen Winkler, Fred H. Gage, Cédric Bardy
Journal Name:npj Parkinson's Disease
Publisher:Springer Science and Business Media LLC
Vol:8
Issue #:1
Start Page:134
End Page:134
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by
DOI - Digital Object Identifier:10.1038/s41531-022-00400-0
We use cookies to ensure that you get the best experience. By continuing to use this website, you indicate that you have read our
Terms of Service and Privacy Policy.