2201 - 2210 of 8620 Results
Title
Year
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OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29
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OPENTitle: Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 17Start Page: 4967End Page: 4970Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2009.07.072Best OA location URL: https://doi.org/10.7270/q2tb16zxCitation Count: 36
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OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Best OA location URL: https://doi.org/10.7270/q2s75grqCitation Count: 18
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulatorsJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 18Issue #: 20Start Page: 5626End Page: 5630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.08.087Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3182458Citation Count: 58
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OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 85
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-leadJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 3Start Page: 962End Page: 966Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.11.104Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3787871Citation Count: 55
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OPENTitle: Role of Elongation and Secondary Pathways in S6 Amyloid Fibril GrowthJournal Name: Biophysical JournalPublisher: Elsevier BVVol: 102Issue #: 9Start Page: 2167End Page: 2175Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.bpj.2012.03.047Best OA location URL: http://www.cell.com/article/S0006349512003888/pdfCitation Count: 36
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OPENTitle: Discovery and characterization of a novel series of N -phenylsulfonyl-1 H -pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu 4 )Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4955388Citation Count: 5
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OPENTitle: Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutationsJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 35Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20150128Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/35/5/e00254/477473/bsr035e254.pdfCitation Count: 27
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OPENTitle: Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 2Issue #: 28Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3000664Best OA location URL: http://doi.org/10.1126/scitranslmed.3000664Citation Count: 135