2381 - 2390 of 8620 Results
Title
Year
-
OPENTitle: Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)Journal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 52Issue #: 14Start Page: 4115End Page: 4118Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm9005065Best OA location URL: http://doi.org/10.1021/jm9005065Citation Count: 80
-
OPENTitle: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 53Issue #: 15Start Page: 5476End Page: 5490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm100027pBest OA location URL: https://doi.org/10.7270/q2dr2vqfCitation Count: 84
-
OPENTitle: Enantiomeric Propanolamines as selectiveN-Methyl-d-aspartate 2B Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 51Issue #: 18Start Page: 5506End Page: 5521Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm8002153Best OA location URL: https://doi.org/10.7270/q2pz59qhCitation Count: 26
-
OPENTitle: Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal ModelJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 21Start Page: 7639End Page: 7647Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm200956qCitation Count: 59
-
OPENTitle: Structure–Activity Relationship of N,N′-Disubstituted Pyrimidinetriones as CaV1.3 Calcium Channel-Selective Antagonists for Parkinson’s DiseaseJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 56Issue #: 11Start Page: 4786End Page: 4797Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm4005048Best OA location URL: http://doi.org/10.1021/jm4005048Citation Count: 30
-
OPENTitle: Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in RatsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 4Start Page: 1106End Page: 1110Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm101271sCitation Count: 48
-
OPENTitle: Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced ToxicityJournal Name: Journal of Molecular BiologyPublisher: Elsevier BVVol: 368Issue #: 4Start Page: 1132End Page: 1144Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jmb.2007.02.089Best OA location URL: http://doi.org/10.1016/j.jmb.2007.02.089Citation Count: 151
-
OPENTitle: 7T MRI subthalamic nucleus atlas for use with 3T MRIJournal Name: Journal of Medical ImagingPublisher: SPIE-Intl Soc Optical EngVol: 5Issue #: 01Start Page: 1End Page: 1Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1117/1.jmi.5.1.015002Best OA location URL: https://www.spiedigitallibrary.org/journals/journal-of-medical-imaging/volume-5/issue-1/015002/7T-MRI-subthalamic-nucleus-atlas-for-use-with-3T-MRI/10.1117/1.JMI.5.1.015002.pdfCitation Count: 16
-
OPENTitle: Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding ActivitiesJournal Name: Journal of Molecular BiologyPublisher: Elsevier BVVol: 412Issue #: 1Start Page: 94End Page: 110Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jmb.2011.07.033Citation Count: 123
-
OPENTitle: LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell modelsJournal Name: Journal of Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 91Issue #: 4Start Page: 513End Page: 522Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00109-012-0984-yBest OA location URL: https://link.springer.com/content/pdf/10.1007/s00109-012-0984-y.pdfCitation Count: 74