3321 - 3330 of 9134 Results
Title
Year
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OPENTitle: Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 109Issue #: 26Start Page: 10322End Page: 10327Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1203223109Best OA location URL: https://www.pnas.org/content/pnas/109/26/10322.full.pdfCitation Count: 99
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RESTRICTEDTitle: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 107Issue #: 21Start Page: 9879End Page: 9884Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.1004676107Best OA location URL: http://doi.org/10.1073/pnas.1004676107Citation Count: 510
- Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas2011RESTRICTEDTitle: Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomasJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 4Start Page: 1439End Page: 1444Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.1012500108Citation Count: 95
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OPENTitle: In vivo demonstration that α-synuclein oligomers are toxicJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 10Start Page: 4194End Page: 4199Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1100976108Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976Citation Count: 1494
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OPENTitle: Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 109Issue #: 39Start Page: 15918End Page: 15923Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1205102109Best OA location URL: https://www.pnas.org/content/pnas/109/39/15918.full.pdfCitation Count: 87
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OPENTitle: R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 34Start Page: 14622End Page: 14627Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0906334106Best OA location URL: http://doi.org/10.1073/pnas.0906334106Citation Count: 313
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 122
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 41Start Page: E3945End Page: 54Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/94836Citation Count: 213
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 224
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OPENTitle: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 27Start Page: 11441End Page: 11446Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0702717104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0702717104Citation Count: 539