2576 - 2600 of 9134 Results
Title
Year
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OPENTitle: Efficient estimation of nonparametric genetic risk function with censored dataJournal Name: BiometrikaPublisher: Oxford University Press (OUP)Vol: 102Issue #: 3Start Page: 515End Page: 532Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/biomet/asv030Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4581539Citation Count: 7
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-leadJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 3Start Page: 962End Page: 966Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.11.104Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3787871Citation Count: 58
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulatorsJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 18Issue #: 20Start Page: 5626End Page: 5630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.08.087Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3182458Citation Count: 59
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OPENTitle: Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samplesJournal Name: Biotechnology ProgressPublisher: WileyVol: 29Issue #: 2Start Page: 463End Page: 471Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/btpr.1698Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3618510Citation Count: 24
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OPENTitle: Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 17Start Page: 4967End Page: 4970Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2009.07.072Best OA location URL: http://doi.org/10.1016/j.bmcl.2009.07.072Citation Count: 38
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OPENTitle: Identifying blood-brain-barrier selective single-chain antibody fragmentsJournal Name: Biotechnology JournalPublisher: WileyVol: 9Issue #: 5Start Page: 664End Page: 674Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/biot.201300550Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4073886Citation Count: 23
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OPENTitle: Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutationsJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 35Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20150128Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/35/5/e00254/477473/bsr035e254.pdfCitation Count: 27
- Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulator2011OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Citation Count: 18
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OPENTitle: Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGEJournal Name: BMC BioinformaticsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page: 475End Page: 475Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2105-7-475Best OA location URL: https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-475Citation Count: 38
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OPENTitle: Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: http://doi.org/10.1016/j.bmcl.2016.05.029Citation Count: 5
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OPENTitle: Toxic Oligomeric Alpha-Synuclein Variants Present in Human Parkinson’s Disease Brains Are Differentially Generated in Mammalian Cell ModelsJournal Name: BiomoleculesPublisher: MDPI AGVol: 5Issue #: 3Start Page: 1634End Page: 1651Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/biom5031634Best OA location URL: http://hdl.handle.net/2286/R.I.43313Citation Count: 40
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OPENTitle: Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's diseaseJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 424Issue #: 1Start Page: 47End Page: 60Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1042/bj20091035Best OA location URL: https://portlandpress.com/biochemj/article-pdf/424/1/47/659876/bj4240047.pdfCitation Count: 203
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RESTRICTEDTitle: Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycleJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 456Issue #: 1Start Page: 119End Page: 128Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1042/bj20121772Best OA location URL: http://doi.org/10.1042/BJ20121772Citation Count: 97
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OPENTitle: S-Nitrosylation of ApoE in Alzheimer’s DiseaseJournal Name: BiochemistryPublisher: American Chemical Society (ACS)Vol: 50Issue #: 17Start Page: 3405End Page: 3407Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/bi200266vBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3082618Citation Count: 43
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OPENTitle: Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modulesJournal Name: BioinformaticsPublisher: Oxford University Press (OUP)Vol: 33Issue #: 20Start Page: 3250End Page: 3257Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/bioinformatics/btx344Best OA location URL: https://academic.oup.com/bioinformatics/article-pdf/33/20/3250/28016045/btx344.pdfCitation Count: 25
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OPENTitle: Hybrid Bayesian-rank integration approach improves the predictive power of genomic dataset aggregationJournal Name: BioinformaticsPublisher: Oxford University Press (OUP)Vol: 31Issue #: 2Start Page: 209End Page: 215Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/bioinformatics/btu518Best OA location URL: https://academic.oup.com/bioinformatics/article-pdf/31/2/209/17125420/btu518.pdfCitation Count: 23
- The Thorny Problem of Dyskinesias: Dendritic Spines, Synaptic Plasticity, and Striatal Dysfunction2014OPENTitle: The Thorny Problem of Dyskinesias: Dendritic Spines, Synaptic Plasticity, and Striatal DysfunctionJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 75Issue #: 9Start Page: 676End Page: 677Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2014.02.019Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4120525Citation Count: 1
- Selective Knockout of the Casein Kinase 2 in D1 Medium Spiny Neurons Controls Dopaminergic Function2013OPENTitle: Selective Knockout of the Casein Kinase 2 in D1 Medium Spiny Neurons Controls Dopaminergic FunctionJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 74Issue #: 2Start Page: 113End Page: 121Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2012.11.013Best OA location URL: http://doi.org/10.1016/j.biopsych.2012.11.013Citation Count: 46
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OPENTitle: Efficient determination of purine metabolites in brain tissue and serum by high‐performance liquid chromatography with electrochemical and UV detectionJournal Name: Biomedical ChromatographyPublisher: WileyVol: 27Issue #: 1Start Page: 122End Page: 129Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/bmc.2760Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9979337Citation Count: 29
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OPENTitle: Striatal Overexpression of ΔJunD Resets L-DOPA-Induced Dyskinesia in a Primate Model of Parkinson DiseaseJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 66Issue #: 6Start Page: 554End Page: 561Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2009.04.005Best OA location URL: http://doi.org/10.1016/j.biopsych.2009.04.005Citation Count: 97
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OPENTitle: Alternative Splicing Regulation of an Alzheimer’s Risk Variant in CLUJournal Name: International Journal of Molecular SciencesPublisher: MDPI AGVol: 21Issue #: 19Start Page: 7079End Page: 7079Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/ijms21197079Best OA location URL: https://www.mdpi.com/1422-0067/21/19/7079/pdf?version=1601037001Citation Count: 16
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OPENTitle: Well Water and Parkinson’s Disease in Medicare Beneficiaries: A Nationwide Case-Control StudyJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 10Issue #: 2Start Page: 693End Page: 705Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-191793Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7342021Citation Count: 11
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OPENTitle: Challenges and innovations in brain PET analysis of neurodegenerative disorders: a mini-review on partial volume effects, small brain region studies, and reference region selectionJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 17Issue #:Start Page: 1293847End Page: 1293847Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2023.1293847Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2023.1293847/pdf?isPublishedV2=FalseCitation Count: 17
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OPENTitle: The D1/D5 Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson’s Disease: A Feasibility StudyJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 10Issue #: 4Start Page: 1515End Page: 1527Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-202188Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8640973Citation Count: 31
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OPENTitle: Substantia Nigra Volume Dissociates Bradykinesia and Rigidity from Tremor in Parkinson’s Disease: A 7 Tesla Imaging StudyJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 10Issue #: 2Start Page: 591End Page: 604Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-191890Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd191890?id=journal-of-parkinsons-disease%2Fjpd191890Citation Count: 33