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  • Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
    2012
    Summary Details
    OPEN
    Title: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
    Author(s): Arthur G. Fitzmaurice, Shannon Rhodes, Aaron Lulla, Niall Murphy, Hoa A. Lam, Kelley C. O’Donnell, Lisa M. Barnhill, John E. Casida, Myles Cockburn, Alvaro Sagasti, Mark Stahl, Nigel T. Maidment, Beate Ritz, Jeff M. Bronstein
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 110
    Issue #: 2
    Start Page: 636
    End Page: 641
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1220399110
    Best OA location URL: https://www.pnas.org/content/pnas/110/2/636.full.pdf
    Citation Count: 193
  • In vitro high affinity α‐synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain1
    2008
    Summary Details
    OPEN
    Title: In vitro high affinity α‐synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain1
    Author(s): Liang Ye, Ana Luisa Velasco, Graham Fraser, Thomas G. Beach, Lucia I. Sue, Tracy Osredkar, Vincenzo Libri, Maria Grazia Spillantini, Michel Goedert, Andrew Lockhart
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 105
    Issue #: 4
    Start Page: 1428
    End Page: 1437
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2008.05245.x
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1471-4159.2008.05245.x
    Citation Count: 92
  • Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease
    2012
    Summary Details
    OPEN
    Title: Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease
    Author(s): Maxime W.C. Rousseaux, Paul C. Marcogliese, Dianbo Qu, Sarah J. Hewitt, Sarah Seang, Raymond H. Kim, Ruth S. Slack, Michael G. Schlossmacher, Diane C. Lagace, Tak W. Mak, David S. Park
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 109
    Issue #: 39
    Start Page: 15918
    End Page: 15923
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1205102109
    Best OA location URL: https://www.pnas.org/content/pnas/109/39/15918.full.pdf
    Citation Count: 87
  • A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    2018
    Summary Details
    OPEN
    Title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    Author(s): Hongjun Fu, Andrea Possenti, Rosie Freer, Yoshikazu Nakano, Nancy C. Hernandez Villegas, Maoping Tang, Paula Victoria Maglio Cauhy, Benjamin Lassus, Shuo Chen, Stephanie L. Fowler, Helen Y. Figueroa, Edward D. Huey, Gail V.W. Johnson, Michele Vendruscolo, Karen Duff
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 22
    Issue #: 1
    Start Page: 47
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7
    Citation Count: 217
  • In vivo demonstration that α-synuclein oligomers are toxic
    2011
    Summary Details
    OPEN
    Title: In vivo demonstration that α-synuclein oligomers are toxic
    Author(s): Beate Winner, Roberto Jappelli, Samir K. Maji, Paula Desplats, Leah Boyer, Stefan Aigner, Claudia Hetzer, Thomas Loher, Marçal Vilar, Silvia Campioni, Christos Tzitzilonis, Alice Soragni, Sebastian Jessberger, Helena Mira, Antonella Consiglio, Emiley Pham, Eliezer Masliah, Fred H. Gage, Roland Riek
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 108
    Issue #: 10
    Start Page: 4194
    End Page: 4199
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1100976108
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976
    Citation Count: 1395
  • The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions
    2017
    Summary Details
    OPEN
    Title: The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions
    Author(s): María Dolores Pérez‐Carrión, Silvia Marsicano, Federica Daniele, Antonella Marte, Francesca Pischedda, Eliana Di Cairano, Ester Piovesana, Felix von Zweydorf, Elisabeth Kremmer, Christian Johannes Gloeckner, Franco Onofri, Carla Perego, Giovanni Piccoli
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-017-05760-9
    Best OA location URL: https://www.nature.com/articles/s41598-017-05760-9.pdf
    Citation Count: 64
  • Fusion to a highly charged proteasomal retargeting sequence increases soluble cytoplasmic expression and efficacy of diverse anti-synuclein intrabodies
    2012
    Summary Details
    OPEN
    Title: Fusion to a highly charged proteasomal retargeting sequence increases soluble cytoplasmic expression and efficacy of diverse anti-synuclein intrabodies
    Author(s): Shubhada N. Joshi, David C. Butler, Anne Messer
    Journal Name: mAbs
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 6
    Start Page: 686
    End Page: 693
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.4161/mabs.21696
    Best OA location URL: https://www.tandfonline.com/doi/pdf/10.4161/mabs.21696?needAccess=true
    Citation Count: 68
  • Age-specific penetrance ofLRRK2G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium
    2015
    Summary Details
    OPEN
    Title: Age-specific penetrance ofLRRK2G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium
    Author(s): Karen Marder, Yuanjia Wang, Roy N. Alcalay, Helen Mejia‐Santana, Ming‐Xin Tang, Annie Lee, Deborah Raymond, Anat Mirelman, Rachel Saunders‐Pullman, Lorraine N. Clark, Laurie J. Ozelius, Avi Orr‐Urtreger, Nir Giladi, Susan Bressman, Roy N. Alcalay, Ming-X Tang, Helen Mejia Santana, Ernest Roos, Martha Orbe‐Reilly, Stanley Fahn, Lucien Côté, Cheryl Waters, Pietro Mazzoni, Blair Ford, Elan D. Louis, Oren Levy, Llency Rosado, Dylanis Lopez Ruiz, Tsvyatko Dorovski, Paul Greene, Lorraine N. Clark, Karen Marder, Tanya Gurevich, Anat Bar Shira, Mali Gana Weisz, Kira Yasinovsky, Maayan Zalis, Avner Thaler, Yaacov Balash, Shabtai Hertzel, Ziv Gan‐Or, Hila Kobo, Ariella Hillel, Anat Shkedy, Avi Orr‐Urtreger, Nir Giladi, Andres Deik, Matthew J. Barrett, Jose Cabassa, Mark Groves, Ann Hunt, Naomi Lubarr, Marta San Luciano, Joan Miravite, Christina A. Palmese, Rivka Sachdev, Harini Sarva, Lawrence Severt, Vicki Shanker, Matthew Swan, Jeannie Soto‐Valencia, Brooke Johannes, Robert Ortega, Laurie J. Ozelius, Rachel Saunders‐Pullman, Deborah Raymond, Susan Bressman
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 85
    Issue #: 1
    Start Page: 89
    End Page: 95
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000001708
    Best OA location URL: https://n.neurology.org/content/neurology/85/1/89.full.pdf
    Citation Count: 158
  • Pure hereditary spastic paraplegia due to a de novo mutation in the NIPA1 gene
    2013
    Summary Details
    OPEN
    Title: Pure hereditary spastic paraplegia due to a de novo mutation in the NIPA1 gene
    Author(s): David Arkadir, Anne Noreau, Jill Goldman, Guy A. Rouleau, Roy N. Alcalay
    Journal Name: European Journal of Neurology
    Publisher: Wiley
    Vol: 21
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ene.12284
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4138605
    Citation Count: 8
  • Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer’s disease
    2011
    Summary Details
    OPEN
    Title: Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer’s disease
    Author(s): Pamela E. Potter, Paula K. Rauschkolb, Yoga Pandya, Lucia I. Sue, Marwan N. Sabbagh, Douglas G. Walker, Thomas G. Beach
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 122
    Issue #: 1
    Start Page: 49
    End Page: 60
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00401-011-0831-1
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3362487
    Citation Count: 93
  • The relationship between obsessive‐compulsive symptoms and PARKIN genotype: The CORE‐PD study
    2014
    Summary Details
    OPEN
    Title: The relationship between obsessive‐compulsive symptoms and PARKIN genotype: The CORE‐PD study
    Author(s): Madeleine Sharp, Elise Caccappolo, Helen Mejia‐Santana, Ming‐X. Tang, Llency Rosado, Martha Orbe Reilly, Dylanis Lopez Ruiz, Elan D. Louis, Cynthia Comella, Martha Nance, Susan Bressman, William K. Scott, Caroline M. Tanner, Cheryl Waters, Stanley Fahn, Lucien Côté, Blair Ford, Michael Rezak, Kevin Novak, Joseph H. Friedman, Ronald F. Pfeiffer, Haydeh Payami, Eric Molho, S. A. Factor, John G. Nutt, Carmen Serrano, Maritza Arroyo, Michael W. Pauciulo, William C. Nichols, Lorraine N. Clark, Roy N. Alcalay, Karen Marder
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 30
    Issue #: 2
    Start Page: 278
    End Page: 283
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26065
    Best OA location URL: http://doi.org/10.1002/mds.26065
    Citation Count: 19
  • Peptidoglycan recognition protein genes and risk of Parkinson's disease
    2014
    Summary Details
    OPEN
    Title: Peptidoglycan recognition protein genes and risk of Parkinson's disease
    Author(s): Samuel M. Goldman, Freya Kamel, G. Webster Ross, Sarah A. Jewell, Connie Marras, Jane A. Hoppin, David M. Umbach, Grace S. Bhudhikanok, Cheryl Meng, Monica Korell, Kathleen Comyns, Robert A. Hauser, Joseph Jankovic, Stewart A. Factor, Susan Bressman, Kelly E. Lyons, Dale P. Sandler, J. William Langston, Caroline M. Tanner
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 29
    Issue #: 9
    Start Page: 1171
    End Page: 1180
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25895
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4777298
    Citation Count: 48
  • Results of the citalopram to enhance cognition in Huntington disease trial
    2013
    Summary Details
    OPEN
    Title: Results of the citalopram to enhance cognition in Huntington disease trial
    Author(s): Leigh J. Beglinger, William Adams, Douglas R. Langbehn, Jess G. Fiedorowicz, Ricardo E. Jorge, Kevin Biglan, John N. Caviness, Blair Olson, Robert G. Robinson, Karl Kieburtz, Jane S. Paulsen
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 29
    Issue #: 3
    Start Page: 401
    End Page: 405
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25750
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3960314
    Citation Count: 59
  • The Unified Parkinson�s Disease Rating Scale as a predictor of peak aerobic capacity and ambulatory function
    2012
    Summary Details
    OPEN
    Title: The Unified Parkinson�s Disease Rating Scale as a predictor of peak aerobic capacity and ambulatory function
    Author(s): Frederick M. Ivey, Leslie I. Katzel, John D. Sorkin, Richard F. Macko, Lisa M. Shulman
    Journal Name: The Journal of Rehabilitation Research and Development
    Publisher: Journal of Rehabilitation Research & Development
    Vol: 49
    Issue #: 8
    Start Page: 1269
    End Page: 1269
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1682/jrrd.2011.06.0103
    Citation Count: 27
  • Reliability of a new scale for essential tremor
    2012
    Summary Details
    OPEN
    Title: Reliability of a new scale for essential tremor
    Author(s): Rodger J. Elble, Cynthia Comella, Stanley Fahn, Mark Hallett, Joseph Jankovic, Jorge L. Juncos, Peter A. LeWitt, Kelly E. Lyons, William G. Ondo, Rajesh Pahwa, Kapil D. Sethi, Natividad Stover, Daniel Tarsy, Claudia Testa, Ron Tintner, Ray L. Watts, Theresa Zesiewicz
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 27
    Issue #: 12
    Start Page: 1567
    End Page: 1569
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25162
    Best OA location URL: http://doi.org/10.1002/mds.25162
    Citation Count: 211
  • Impaired perception of biological motion in Parkinson’s disease.
    2016
    Summary Details
    OPEN
    Title: Impaired perception of biological motion in Parkinson’s disease.
    Author(s): Abhishek Jaywant, Maggie Shiffrar, Serge H. Roy, Alice Cronin‐Golomb
    Journal Name: Neuropsychology
    Publisher: American Psychological Association (APA)
    Vol: 30
    Issue #: 6
    Start Page: 720
    End Page: 730
    Publication Date:
    Open Access(OA) Status: OPEN
    License: other-oa
    DOI - Digital Object Identifier: 10.1037/neu0000276
    Best OA location URL: https://doi.org/10.1037/neu0000276
    Citation Count: 51
  • Evaluation of the D3 dopamine receptor selective antagonist PG01037 on l-dopa-dependent abnormal involuntary movements in rats
    2009
    Summary Details
    OPEN
    Title: Evaluation of the D3 dopamine receptor selective antagonist PG01037 on l-dopa-dependent abnormal involuntary movements in rats
    Author(s): Rakesh Kumar, Lindsay R. Riddle, Suzy A. Griffin, Peter Grundt, Amy Hauck Newman, Robert R. Luedtke
    Journal Name: Neuropharmacology
    Publisher: Elsevier BV
    Vol: 56
    Issue #: 6-7
    Start Page: 944
    End Page: 955
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuropharm.2009.01.020
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3820009
    Citation Count: 46
  • Morphological Alterations in the Thalamus, Striatum, and Pallidum in Autism Spectrum Disorder
    2016
    Summary Details
    OPEN
    Title: Morphological Alterations in the Thalamus, Striatum, and Pallidum in Autism Spectrum Disorder
    Author(s): Manuela Schuetze, Min Tae M Park, Ivy YK Cho, Frank P. MacMaster, M. Mallar Chakravarty, Signe Bray
    Journal Name: Neuropsychopharmacology
    Publisher: Springer Science and Business Media LLC
    Vol: 41
    Issue #: 11
    Start Page: 2627
    End Page: 2637
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/npp.2016.64
    Best OA location URL: https://www.nature.com/articles/npp201664.pdf
    Citation Count: 148
  • Prefrontal White Matter Structure Mediates the Influence of GAD1 on Working Memory
    2016
    Summary Details
    OPEN
    Title: Prefrontal White Matter Structure Mediates the Influence of GAD1 on Working Memory
    Author(s): Tristram A. Lett, Kristen M. Kennedy, Natasha Radhu, Luis García Domínguez, M. Mallar Chakravarty, Arash Nazeri, Faranak Farzan, Henrik Walter, Andreas Heinz, Benoit H. Mulsant, Zafiris J. Daskalakis, Aristotle N. Voineskos
    Journal Name: Neuropsychopharmacology
    Publisher: Springer Science and Business Media LLC
    Vol: 41
    Issue #: 9
    Start Page: 2224
    End Page: 2231
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/npp.2016.14
    Best OA location URL: https://www.nature.com/articles/npp201614.pdf
    Citation Count: 27
  • mGlu1 and mGlu5 modulate distinct excitatory inputs to the nucleus accumbens shell
    2018
    Summary Details
    OPEN
    Title: mGlu1 and mGlu5 modulate distinct excitatory inputs to the nucleus accumbens shell
    Author(s): Brandon D. Turner, Jerri M. Rook, Craig W. Lindsley, P. Jeffrey Conn, Brad A. Grueter
    Journal Name: Neuropsychopharmacology
    Publisher: Springer Science and Business Media LLC
    Vol: 43
    Issue #: 10
    Start Page: 2075
    End Page: 2082
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41386-018-0049-1
    Best OA location URL: https://www.nature.com/articles/s41386-018-0049-1.pdf
    Citation Count: 30
  • Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    2009
    Summary Details
    OPEN
    Title: Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    Author(s): Kambiz N. Alavian, Paola Sgadó, Lavinia Albéri, Srinivasa Subramaniam, Horst H. Simon
    Journal Name: Neural Development
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1749-8104-4-11
    Best OA location URL: https://neuraldevelopment.biomedcentral.com/counter/pdf/10.1186/1749-8104-4-11
    Citation Count: 40
  • Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging
    2012
    Summary Details
    OPEN
    Title: Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging
    Author(s): Brittany N. Dugger, Geidy E. Serrano, Lucia I. Sue, Douglas G. Walker, Charles H. Adler, Holly A. Shill, Marwan N. Sabbagh, John N. Caviness, José A. Hidalgo, Megan Saxon‐LaBelle, Glenn Chiarolanza, Monica Mariner, Jonette Henry-Watson, Thomas G. Beach
    Journal Name: Journal of Parkinson’s Disease
    Publisher: SAGE Publications
    Vol: 2
    Issue #: 1
    Start Page: 57
    End Page: 65
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3233/jpd-2012-11073
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3423968
    Citation Count: 40
  • Expert Testimony at the Food and Drug Administration: Who Wants the Truth?
    2011
    Summary Details
    OPEN
    Title: Expert Testimony at the Food and Drug Administration: Who Wants the Truth?
    Author(s): Joel S. Perlmutter
    Journal Name: Narrative Inquiry in Bioethics
    Publisher: Project MUSE
    Vol: 1
    Issue #: 2
    Start Page: 78
    End Page: 82
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1353/nib.2011.0046
    Citation Count: 0
  • Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease
    2015
    Summary Details
    OPEN
    Title: Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease
    Author(s): Maike Hartlage‐Rübsamen, Alexander Waniek, Juliane Meißner, Markus Morawski, Stephan Schilling, Carsten Jäger, Martin Kleinschmidt, Holger Cynis, Astrid Kehlen, Thomas Arendt, Hans‐Ulrich Demuth, Steffen Roßner
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 129
    Issue #: 4
    Start Page: 565
    End Page: 583
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-015-1395-2
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-015-1395-2.pdf
    Citation Count: 50
  • Models for LRRK2-Linked Parkinsonism
    2011
    Summary Details
    OPEN
    Title: Models for LRRK2-Linked Parkinsonism
    Author(s): Tianxia Li, Dejun Yang, Sarah Sushchky, Zhaohui Liu, Wanli W. Smith
    Journal Name: Parkinson's Disease
    Publisher: Wiley
    Vol: 2011
    Issue #:
    Start Page: 1
    End Page: 16
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.4061/2011/942412
    Best OA location URL: https://downloads.hindawi.com/journals/pd/2011/942412.pdf
    Citation Count: 35
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