3926 - 3950 of 8808 Results
Title
Year
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OPENTitle: LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell modelsJournal Name: Journal of Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 91Issue #: 4Start Page: 513End Page: 522Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00109-012-0984-yBest OA location URL: https://link.springer.com/content/pdf/10.1007/s00109-012-0984-y.pdfCitation Count: 74
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OPENTitle: Select E2 enzymes differentially regulate parkin activation and mitophagyJournal Name: Journal of Cell SciencePublisher: The Company of BiologistsVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1242/jcs.147520Best OA location URL: http://doi.org/10.1242/jcs.147520Citation Count: 69
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OPENTitle: Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep32583Best OA location URL: https://www.nature.com/articles/srep32583.pdfCitation Count: 22
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OPENTitle: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 115Issue #: 22Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1718946115Best OA location URL: https://www.pnas.org/content/pnas/115/22/E5164.full.pdfCitation Count: 109
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OPENTitle: Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neuronsJournal Name: Journal of Neuroscience ResearchPublisher: WileyVol: 89Issue #: 3Start Page: 406End Page: 417Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/jnr.22549Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6487665Citation Count: 17
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OPENTitle: APOE,MAPT, andSNCAGenes and Cognitive Performance in Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 71Issue #: 11Start Page: 1405End Page: 1405Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2014.1455Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/1900308/noi140049.pdfCitation Count: 196
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OPENTitle: Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson’s disease: an observational and case–control studyJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/npjparkd.2015.2Best OA location URL: https://escholarship.org/uc/item/48r6x3tjCitation Count: 135
- GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease2015OPENTitle: GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 1Start Page: 95End Page: 102Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26359Citation Count: 189
- Domain-specific accuracy of the Montreal Cognitive Assessment subsections in Parkinson's disease2017OPENTitle: Domain-specific accuracy of the Montreal Cognitive Assessment subsections in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 38Issue #:Start Page: 31End Page: 34Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.02.008Citation Count: 59
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OPENTitle: Activation of the unfolded protein response enhances motor recovery after spinal cord injuryJournal Name: Cell Death & DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 2Start Page: e272End Page: e272Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/cddis.2012.8Best OA location URL: https://www.nature.com/articles/cddis20128.pdfCitation Count: 137
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OPENTitle: Parkinson disease and incidental Lewy body diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 85Issue #: 19Start Page: 1670End Page: 1679Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000002102Best OA location URL: https://n.neurology.org/content/neurology/85/19/1670.full.pdfCitation Count: 109
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OPENTitle: Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's diseaseJournal Name: Behavioural Brain ResearchPublisher: Elsevier BVVol: 230Issue #: 2Start Page: 309End Page: 316Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bbr.2011.12.007Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3324279Citation Count: 145
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OPENTitle: LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complexJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2014.00049Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2014.00049/pdfCitation Count: 97
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OPENTitle: Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian ratsJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 60Issue #: 6Start Page: 861End Page: 868Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2010.12.032Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3133531Citation Count: 71
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RESTRICTEDTitle: Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structuresJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 118Issue #: 5Start Page: 795End Page: 808Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s00702-011-0653-2Citation Count: 281
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OPENTitle: Screening for Novel LRRK2 Inhibitors Using a High-Throughput TR-FRET Cellular Assay for LRRK2 Ser935 PhosphorylationJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 8Start Page: e43580End Page: e43580Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0043580Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043580&type=printableCitation Count: 38
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OPENTitle: Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4Journal Name: Molecular PharmacologyPublisher: Elsevier BVVol: 74Issue #: 5Start Page: 1345End Page: 1358Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1124/mol.108.049551Best OA location URL: http://doi.org/10.1124/mol.108.049551Citation Count: 185
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OPENTitle: Extra‐nigral pathological conditions are common in Parkinson's disease with freezing of gait: An in vivo positron emission tomography studyJournal Name: Movement DisordersPublisher: WileyVol: 29Issue #: 9Start Page: 1118End Page: 1124Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25929Best OA location URL: http://doi.org/10.1002/mds.25929Citation Count: 112
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OPENTitle: Sensitivity to change and prediction of global change for the Alzheimer’s QuestionnaireJournal Name: Alzheimer's Research & TherapyPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13195-014-0092-zBest OA location URL: https://alzres.biomedcentral.com/track/pdf/10.1186/s13195-014-0092-zCitation Count: 129
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OPENTitle: 4-amino-7-chloroquinoline derivatives for treating Parkinson’s disease: implications for drug discoveryJournal Name: Expert Opinion on Drug DiscoveryPublisher: Informa UK LimitedVol: 11Issue #: 4Start Page: 337End Page: 341Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1517/17460441.2016.1154529Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1517/17460441.2016.1154529?needAccess=trueCitation Count: 18
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OPENTitle: Autonomic complaints in patients with restless legs syndromeJournal Name: Sleep MedicinePublisher: Elsevier BVVol: 14Issue #: 12Start Page: 1413End Page: 1416Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.sleep.2013.08.781Best OA location URL: http://doi.org/10.1016/j.sleep.2013.08.781Citation Count: 31
- LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP62012OPENTitle: LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6Journal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 21Issue #: 22Start Page: 4966End Page: 4979Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds342Best OA location URL: https://academic.oup.com/hmg/article-pdf/21/22/4966/17257652/dds342.pdfCitation Count: 101
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OPENTitle: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 53Issue #: 15Start Page: 5476End Page: 5490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm100027pCitation Count: 84
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OPENTitle: Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal ModelJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 21Start Page: 7639End Page: 7647Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm200956qCitation Count: 59
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OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 85