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  • ELISA method to detect α-synuclein oligomers in cell and animal models
    2018
    Summary Details
    OPEN
    Title: ELISA method to detect α-synuclein oligomers in cell and animal models
    Author(s): Louise Berkhoudt Lassen, Emil Gregersen, Anne Kathrine Isager, Cristine Betzer, Rikke Hahn Kofoed, Poul Henning Jensen, Louise Berkhoudt Lassen, Emil Gregersen, Anne Kathrine Isager, Cristine Betzer, Rikke Hahn Kofoed, Poul Henning Jensen
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 13
    Issue #: 4
    Start Page: e0196056
    End Page: e0196056
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0196056
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0196056&type=printable
    Citation Count: 74
  • Small-scale protocols to characterize mitochondrial Complex V activity and assembly in peripheral blood mononuclear cells
    2025
    Summary Details
    OPEN
    Title: Small-scale protocols to characterize mitochondrial Complex V activity and assembly in peripheral blood mononuclear cells
    Author(s): Kai Yin Chau, Jan-Willem Taanman, Anthony H. V. Schapira
    Journal Name: PLOS One
    Publisher: Public Library of Science (PLoS)
    Vol: 20
    Issue #: 5
    Start Page: e0323136
    End Page: e0323136
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0323136
    Best OA location URL: https://doi.org/10.1371/journal.pone.0323136
    Citation Count: 2
  • Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks
    2025
    Summary Details
    OPEN
    Title: Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks
    Author(s): Rohit Tripathy, Zachary Frohock, Hong Wang, Gregory A. Cary, Stephen Keegan, Gregory W. Carter, Yi Li
    Journal Name: npj Systems Biology and Applications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41540-025-00519-9
    Best OA location URL: https://www.nature.com/articles/s41540-025-00519-9.pdf
    Citation Count: 0
  • Data-driven characterization of distinct cognitive subtypes in Parkinson’s disease dementia
    2025
    Summary Details
    OPEN
    Title: Data-driven characterization of distinct cognitive subtypes in Parkinson’s disease dementia
    Author(s): Miguel A. Labrador‐Espinosa, Jesús Silva‐Rodríguez, Pablo Mir, Michel J. Grothe
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41531-025-00970-9
    Best OA location URL: https://www.nature.com/articles/s41531-025-00970-9.pdf
    Citation Count: 1
  • Is Gauchian genotyping of GBA1 variants reliable?
    2025
    Summary Details
    OPEN
    Title: Is Gauchian genotyping of GBA1 variants reliable?
    Author(s): Nahid Tayebi, Jens Lichtenberg, Ellen Hertz, Ellen Sidransky
    Journal Name: Communications Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s42003-025-08059-y
    Best OA location URL: https://www.nature.com/articles/s42003-025-08059-y.pdf
    Citation Count: 1
  • Reply to: Is Gauchian genotyping of GBA1 variants reliable?
    2025
    Summary Details
    OPEN
    Title: Reply to: Is Gauchian genotyping of GBA1 variants reliable?
    Author(s): Marco Toffoli, Anthony H.V. Schapira, Fritz J. Sedlazeck, Christos Proukakis
    Journal Name: Communications Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s42003-025-08060-5
    Best OA location URL: https://www.nature.com/articles/s42003-025-08060-5.pdf
    Citation Count: 0
  • GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
    2025
    Summary Details
    OPEN
    Title: GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
    Author(s): Diana Acosta Ingram, Emir Turkes, Tae Yeon Kim, S.T. Vo, Nicholas Sweeney, Marie-Amandine Bonte, Ryan Rutherford, Dominic Julian, Meixia Pan, Jacob Marsh, Andrea R. Argouarch, Min Wu, Douglas W. Scharre, Erica H. Bell, Lawrence S. Honig, Jean Paul Vonsattel, Geidy E. Serrano, Thomas G. Beach, Celeste M. Karch, Aimee W. Kao, Mark E. Hester, Xianlin Han, Hongjun Fu
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41467-025-58585-w
    Best OA location URL: https://doi.org/10.1038/s41467-025-58585-w
    Citation Count: 0
  • Structural pathway for PI3-kinase regulation by VPS15 in autophagy
    2025
    Summary Details
    RESTRICTED
    Title: Structural pathway for PI3-kinase regulation by VPS15 in autophagy
    Author(s): Annan SI Cook, Minghao Chen, Thanh Ngoc Nguyen, Ainara Claveras Cabezudo, Grace Khuu, Shanlin Rao, Samantha N. Garcia, M. Yang, Anthony T. Iavarone, Xuefeng Ren, Michael Lazarou, Gerhard Hummer, James H. Hurley
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/science.adl3787
    Best OA location URL: https://doi.org/10.1126/science.adl3787
    Citation Count: 9
  • Clinical and pathologic features of cognitive-predominant corticobasal degeneration
    2020
    Summary Details
    OPEN
    Title: Clinical and pathologic features of cognitive-predominant corticobasal degeneration
    Author(s): Nobutaka Sakae, Octavio A. Santos, Otto Pedraza, Irene Litvan, Melissa E. Murray, Ranjan Duara, Ryan J. Uitti, Zbigniew K. Wszołek, Neill R. Graff‐Radford, Keith A. Josephs, Dennis W. Dickson
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 95
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000009734
    Best OA location URL: https://n.neurology.org/content/neurology/95/1/e35.full.pdf
    Citation Count: 17
  • Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain
    2019
    Summary Details
    OPEN
    Title: Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain
    Author(s): Steven M. Graves, Zhong Xie, Kristen A. Stout, Enrico Zampese, Lena F. Burbulla, Jean C. Shih, Jyothisri Kondapalli, Tommaso Patriarchi, Lin Tian, Lars Brichta, Paul Greengard, Dimitri Krainc, Paul T. Schumacker, D. James Surmeier
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 23
    Issue #: 1
    Start Page: 15
    End Page: 20
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-019-0556-3
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7257994
    Citation Count: 171
  • Seeing ophthalmologic problems in Parkinson disease
    2020
    Summary Details
    OPEN
    Title: Seeing ophthalmologic problems in Parkinson disease
    Author(s): Carlijn D.J.M. Borm, Femke Visser, Mario Werkmann, Debbie de Graaf, Diana Putz, Klaus Seppi, Werner Poewe, Annemarie Vlaar, Carel B. Hoyng, Bastiaan R. Bloem, Thomas Theelen, Nienke M. de Vries
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 94
    Issue #: 14
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000009214
    Best OA location URL: https://n.neurology.org/content/neurology/94/14/e1539.full.pdf
    Citation Count: 58
  • Effects of Moderate Static Magnetic Field on Neural Systems Is a Non-invasive Mechanical Stimulation of the Brain Possible Theoretically?
    2020
    Summary Details
    OPEN
    Title: Effects of Moderate Static Magnetic Field on Neural Systems Is a Non-invasive Mechanical Stimulation of the Brain Possible Theoretically?
    Author(s): A. Hernando, Fernando Gálvez, M. A. Garcı̀a, Vanesa Soto-León, Carlos Alonso-Bonilla, Juan Aguilar, Antonio Oliviero
    Journal Name: Frontiers in Neuroscience
    Publisher: Frontiers Media SA
    Vol: 14
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnins.2020.00419
    Best OA location URL: https://doi.org/10.3389/fnins.2020.00419
    Citation Count: 22
  • Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
    2019
    Summary Details
    OPEN
    Title: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
    Author(s): Amado Carreras‐Sureda, Fabián Jaña, Hery Urra, Sylvère Durand, D.E. Mortenson, Alfredo Sagredo, Galdo Bustos, Younis Hazari, Eva Ramos‐Fernández, Maria Livia Sassano, Philippe Pihán, Alexander R. van Vliet, Matías González-Quiroz, Angie K. Torres, Nibaldo C. Inestrosa, Martijn Kerkhofs, Rubén Vicente, Randal J. Kaufman, Nibaldo C. Inestrosa, Christian González‐Billault, R. Luke Wiseman, Patrizia Agostinis, Geert Bultynck, Felipe A. Court, Guido Kroemer, César Cárdenas, Claudio Hetz
    Journal Name: Nature Cell Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 21
    Issue #: 6
    Start Page: 755
    End Page: 767
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41556-019-0329-y
    Best OA location URL: https://hal.science/hal-04702790
    Citation Count: 194
  • Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease
    2019
    Summary Details
    OPEN
    Title: Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease
    Author(s): Meghan C. Campbell, Joshua J. Jackson, Jonathan M. Koller, Abraham Z. Snyder, Paul T. Kotzbauer, Joel S. Perlmutter
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 94
    Issue #: 7
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000008677
    Best OA location URL: https://n.neurology.org/content/neurology/94/7/e718.full.pdf
    Citation Count: 29
  • Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
    2025
    Summary Details
    OPEN
    Title: Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
    Author(s): Sophie E Mastenbroek, Lyduine E. Collij, Jacob W. Vogel, Serena Caldera, Geidy E. Serrano, Charles H. Adler, Claudia Marina Vargiu, Sebastian Palmqvist, Frederik Barkhof, Piero Parchi, Thomas G. Beach, Rik Ossenkoppele, Oskar Hansson
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-025-62458-7
    Best OA location URL: https://www.nature.com/articles/s41467-025-62458-7.pdf
    Citation Count: 0
  • Enhanced beta power emerges from simulated parkinsonian primary motor cortex
    2025
    Summary Details
    OPEN
    Title: Enhanced beta power emerges from simulated parkinsonian primary motor cortex
    Author(s): Donald Doherty, Liqiang Chen, Yoland Smith, Thomas Wichmann, Hong‐Yuan Chu, William W. Lytton
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-025-01070-4
    Best OA location URL: https://www.nature.com/articles/s41531-025-01070-4.pdf
    Citation Count: 0
  • Rapid frontotemporal gray matter loss in proposed body-first Parkinson’s disease: a longitudinal voxel-based morphometry study
    2025
    Summary Details
    OPEN
    Title: Rapid frontotemporal gray matter loss in proposed body-first Parkinson’s disease: a longitudinal voxel-based morphometry study
    Author(s): Yan Jin, Yao Ge
    Journal Name: Frontiers in Neurology
    Publisher: Frontiers Media SA
    Vol: 16
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fneur.2025.1579561
    Best OA location URL: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1579561/pdf
    Citation Count: 0
  • LRRK2 kinase activity regulates Parkinson’s disease-relevant lipids at the lysosome
    2025
    Summary Details
    OPEN
    Title: LRRK2 kinase activity regulates Parkinson’s disease-relevant lipids at the lysosome
    Author(s): Michael T. Maloney, Xiang Wang, Rajarshi Ghosh, Shan V. Andrews, Romeo Maciuca, Shababa T. Masoud, Maayan Agam, Richard M. Caprioli, Giuseppe Astarita, Vitaliy V. Bondar, John Chen, Chi‐Lu Chiu, Sonnet S. Davis, Audrey Cheuk-Nga Ho, Hoang N. Nguyen, Nicholas E. Propson, Michelle L. Reyzer, Oliver B. Davis, Matthew C. Deen, Sha Zhu, Gilbert Di Paolo, David J. Vocadlo, Anthony A. Estrada, Javier De Vicente, Joseph W. Lewcock, Annie Arguello, Jung H. Suh, Sarah Huntwork‐Rodriguez, Anastasia G. Henry
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 20
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-025-00880-7
    Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-025-00880-7
    Citation Count: 0
  • Subsecond Analysis of Locomotor Activity in Parkinsonian Mice
    2025
    Summary Details
    OPEN
    Title: Subsecond Analysis of Locomotor Activity in Parkinsonian Mice
    Author(s): Daniil Berezhnoi, Hiba Douja Chehade, Gabriel Simms, Liqiang Chen, Kishore Kumar S. Narasimhan, Shashank M. Dravid, Hong‐Yuan Chu
    Journal Name: eneuro
    Publisher: Society for Neuroscience
    Vol: 12
    Issue #: 8
    Start Page: ENEURO.0014
    End Page: 25.2025
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1523/eneuro.0014-25.2025
    Best OA location URL: https://doi.org/10.1523/eneuro.0014-25.2025
    Citation Count: 0
  • Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson’s disease
    2025
    Summary Details
    OPEN
    Title: Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson’s disease
    Author(s): Sreeja V. Nair, Ebsy Jaimon, Ayan Adhikari, Jonas Nikoloff, Suzanne R. Pfeffer
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 122
    Issue #: 31
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2504774122
    Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.2504774122
    Citation Count: 0
  • In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
    2025
    Summary Details
    OPEN
    Title: In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
    Author(s): Kevin Rose, Eric Herrmann, Eve V. Kakudji, Javier Lizarrondo, A. Yasemin Celebi, Florian Wilfling, Samantha C. Lewis, James H. Hurley
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 122
    Issue #: 31
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2511890122
    Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.2511890122
    Citation Count: 1
  • Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery
    2025
    Summary Details
    OPEN
    Title: Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery
    Author(s): Elias Adriaenssens, Stefan Schaar, Annan SI Cook, Jan F. M. Stuke, Justyna Sawa‐Makarska, Thanh Ngoc Nguyen, Xuefeng Ren, Martina Schuschnig, Julia Romanov, Grace Khuu, Louise Uoselis, Michael Lazarou, Gerhard Hummer, James H. Hurley, Sascha Martens
    Journal Name: Nature Cell Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 27
    Issue #: 8
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41556-025-01712-y
    Best OA location URL: https://doi.org/10.1038/s41556-025-01712-y
    Citation Count: 0
  • Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
    2025
    Summary Details
    OPEN
    Title: Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
    Author(s): Mirja Thomsen, Fabian Ott, Sebastian Loens, Gamze Kilic‐Berkmen, Ai Huey Tan, Shen‐Yang Lim, Ebba Lohmann, Katrin Schröder, Lea Ipsen, Lena A. Nothacker, Linn Welzel, Agata Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E. Zeuner, Friederike Schumann, Andrea A. Kühn, Simone Zittel, Marius E. Moeller, Robert M. Pfister, Christoph Kamm, Anthony E. Lang, Yi Wen Tay, Ana Luísa de Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S. Perlmutter, Jeanne Feuerstein, Victor S.C. Fung, Florence Chang, Richard L. Barbano, Steven Bellows, Aparna Wagle Shukla, Alberto J. Espay, Mark S. LeDoux, Brian D. Berman, Stephen G. Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H. A. Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 12
    Issue #: 8
    Start Page: 1648
    End Page: 1659
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/acn3.70100
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.70100
    Citation Count: 1
  • CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline
    2025
    Summary Details
    OPEN
    Title: CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline
    Author(s): J. Muñoz, Arnau Puig‐Davi, Iñigo Ruíz‐Barrio, Javier Pagonabarraga, Anna Vázquez‐Oliver, Andrea Horta‐Barba, Jaime Kulisevsky, Saül Martínez‐Horta
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 12
    Issue #: 8
    Start Page: 1575
    End Page: 1584
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.70075
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.70075
    Citation Count: 0
  • Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease
    2025
    Summary Details
    OPEN
    Title: Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease
    Author(s): Dariia Kuzovenkova, L W Liu, Ziv Gan‐Or, Konstantin Senkevich
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 12
    Issue #: 8
    Start Page: 1706
    End Page: 1710
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/acn3.70076
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.70076
    Citation Count: 0
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