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  • (Patho‐)physiological relevance of PINK 1‐dependent ubiquitin phosphorylation
    2015
    Summary Details
    OPEN
    Title: (Patho‐)physiological relevance of PINK 1‐dependent ubiquitin phosphorylation
    Author(s): Fabienne C. Fiesel, Maya Ando, Roman Hudec, Anneliese R. Hill, Monica Castanedes‐Casey, Thomas R. Caulfield, Elisabeth L. Moussaud-Lamodière, Jeannette N. Stankowski, Peter Bauer, Oswaldo Lorenzo‐Betancor, Isidró Ferrer, José Matías Arbelo, Joanna Siuda, Li Chen, Valina L. Dawson, Ted M. Dawson, Zbigniew K. Wszołek, Owen A. Ross, Dennis W. Dickson, Wolfdieter Springer
    Journal Name: EMBO reports
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 9
    Start Page: 1114
    End Page: 1130
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.15252/embr.201540514
    Best OA location URL: http://doi.org/10.15252/embr.201540514
    Citation Count: 165
  • Ruminative brooding is associated with salience network coherence in early pubertal youth
    2016
    Summary Details
    OPEN
    Title: Ruminative brooding is associated with salience network coherence in early pubertal youth
    Author(s): Sarah J. Ordaz, Joelle LeMoult, Natalie L. Colich, Gautam Prasad, Madeline Pollak, Morgan Popolizio, Alexandra Price, Michael D. Greicius, Ian H. Gotlib
    Journal Name: Social Cognitive and Affective Neuroscience
    Publisher: Oxford University Press (OUP)
    Vol: 12
    Issue #: 2
    Start Page: 298
    End Page: 310
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1093/scan/nsw133
    Best OA location URL: https://academic.oup.com/scan/article-pdf/12/2/298/27104291/nsw133.pdf
    Citation Count: 40
  • Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice
    2014
    Summary Details
    OPEN
    Title: Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice
    Author(s): Gonzalo Sánchez, Rafael K. Varaschin, Hansruedi Büeler, Paul C. Marcogliese, David S. Park, Louis‐Éric Trudeau
    Journal Name: PLoS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 9
    Issue #: 4
    Start Page: e94826
    End Page: e94826
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0094826
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094826&type=printable
    Citation Count: 35
  • Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
    2012
    Summary Details
    OPEN
    Title: Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
    Author(s): Cristian A Lasagna Reeves, Diana L. Castillo‐Carranza, Urmi Sengupta, Marcos J. Guerrero-Muñoz, Takaki Kiritoshi, Volker Neugebauer, George R Jackson, Rakez Kayed, Cristian A Lasagna Reeves, Diana L. Castillo‐Carranza, Urmi Sengupta, Marcos J. Guerrero-Muñoz, Takaki Kiritoshi, Volker Neugebauer, George R Jackson, Rakez Kayed
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 2
    Issue #: 1
    Start Page: 700
    End Page: 700
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1038/srep00700
    Best OA location URL: https://www.nature.com/articles/srep00700.pdf
    Citation Count: 485
  • Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease
    2018
    Summary Details
    OPEN
    Title: Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease
    Author(s): Lingyan Ping, Duc M. Duong, Luming Yin, Marla Gearing, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: Scientific Data
    Publisher: Springer Science and Business Media LLC
    Vol: 5
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/sdata.2018.36
    Best OA location URL: https://www.nature.com/articles/sdata201836.pdf
    Citation Count: 215
  • Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
    2013
    Summary Details
    OPEN
    Title: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
    Author(s): Carmen Noelker, Lydie Morel, Thomas Lescot, Anke Osterloh, Daniel Alvarez‐Fischer, Minka Breloer, Carmen Henze, Candan Depboylu, Delphine Skrzydelski, Patrick P. Michel, Richard C. Dodel, Lixia Lü, Étienne C. Hirsch, Stéphane Hunot, Andréas Hartmann
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/srep01393
    Best OA location URL: https://www.nature.com/articles/srep01393.pdf
    Citation Count: 150
  • Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in Rats
    2011
    Summary Details
    OPEN
    Title: Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in Rats
    Author(s): Darren W. Engers, Julie R. Field, Uyen Le, Ya Zhou, Julie D. Bolinger, Rocio Zamorano, Anna L. Blobaum, Carrie K. Jones, Satyawan Jadhav, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 54
    Issue #: 4
    Start Page: 1106
    End Page: 1110
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm101271s
    Citation Count: 48
  • Cerebral blood flow in Alzheimer’s disease
    2012
    Summary Details
    OPEN
    Title: Cerebral blood flow in Alzheimer’s disease
    Author(s): Alex E. Roher, Debbins, Michael Malek‐Ahmadi, Pipe, Maze, Belden, Maarouf, Hunter, Kokjohn, Walker, Kruchowsky, BĚlohlávek, Mary Catherine Beach, Marwan N. Sabbagh, Kewei Chen, Hua Mo, Pradeep Thiyyagura
    Journal Name: Vascular Health and Risk Management
    Publisher: Informa UK Limited
    Vol:
    Issue #:
    Start Page: 599
    End Page: 599
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.2147/vhrm.s34874
    Best OA location URL: https://www.dovepress.com/getfile.php?fileID=14292
    Citation Count: 187
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 157
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 326
  • Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    2013
    Summary Details
    OPEN
    Title: Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    Author(s): Shireen A. Sarraf, Malavika Raman, Virginia Guarani‐Pereira, Mathew E. Sowa, Edward L. Huttlin, Steven P. Gygi, J. Wade Harper
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 496
    Issue #: 7445
    Start Page: 372
    End Page: 376
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature12043
    Best OA location URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11878916
    Citation Count: 956
  • Measuring mild cognitive impairment in patients with Parkinson's disease
    2013
    Summary Details
    OPEN
    Title: Measuring mild cognitive impairment in patients with Parkinson's disease
    Author(s): Connie Marras, Melissa J. Armstrong, Christopher Meaney, Susan H. Fox, Brandon Rothberg, William Reginold, David F. Tang‐Wai, David Gill, Paul J. Eslinger, Cindy Zadikoff, Nancy Kennedy, Fred Marshall, Mark Mapstone, Kelvin L. Chou, Carol Persad, Irene Litvan, Benjamin T. Mast, Adam Gerstenecker, Sandra Weıntraub, Sarah Duff‐Canning
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 28
    Issue #: 5
    Start Page: 626
    End Page: 633
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25426
    Best OA location URL: https://hdl.handle.net/2027.42/98243
    Citation Count: 134
  • Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease
    2015
    Summary Details
    OPEN
    Title: Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease
    Author(s): Coralie de Hemptinne, Nicole C. Swann, Jill L. Ostrem, Elena Ryapolova-Webb, Marta San Luciano, Nicholas B. Galifianakis, Philip A. Starr
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 18
    Issue #: 5
    Start Page: 779
    End Page: 786
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3997
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4414895
    Citation Count: 581
  • Cortical phosphorylated α‐Synuclein levels correlate with brain wave spectra in Parkinson's disease
    2016
    Summary Details
    OPEN
    Title: Cortical phosphorylated α‐Synuclein levels correlate with brain wave spectra in Parkinson's disease
    Author(s): John N. Caviness, Lih-Fen Lue, Joseph G. Hentz, Christopher T. Schmitz, Charles H. Adler, Holly A. Shill, Marwan N. Sabbagh, Thomas G. Beach, Douglas G. Walker
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 31
    Issue #: 7
    Start Page: 1012
    End Page: 1019
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26621
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4931950
    Citation Count: 35
  • Subliminal gait initiation deficits in rapid eye movement sleep behavior disorder: A harbinger of freezing of gait?
    2016
    Summary Details
    OPEN
    Title: Subliminal gait initiation deficits in rapid eye movement sleep behavior disorder: A harbinger of freezing of gait?
    Author(s): Laila Alibiglou, Aleksandar Videnović, Peggy J. Planetta, David E. Vaillancourt, Colum D. MacKinnon
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 31
    Issue #: 11
    Start Page: 1711
    End Page: 1719
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26665
    Best OA location URL: http://doi.org/10.1002/mds.26665
    Citation Count: 41
  • Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP‐C
    2016
    Summary Details
    OPEN
    Title: Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP‐C
    Author(s): Shunsuke Koga, Keith A. Josephs, Kotaro Ogaki, Catherine Labbé, Ryan J. Uitti, Neill R. Graff‐Radford, Jay A. van Gerpen, William P. Cheshire, Naoya Aoki, Rosa Rademakers, Zbigniew K. Wszołek, Owen A. Ross, Dennis W. Dickson
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 31
    Issue #: 5
    Start Page: 653
    End Page: 662
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26499
    Best OA location URL: http://doi.org/10.1002/mds.26499
    Citation Count: 70
  • R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
    2009
    Summary Details
    OPEN
    Title: R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
    Author(s): Youren Tong, Antonio Pisani, Giuseppina Martella, Maha Karouani, Hiroo Yamaguchi, Emmanuel N. Pothos, Jie Shen
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 106
    Issue #: 34
    Start Page: 14622
    End Page: 14627
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0906334106
    Best OA location URL: http://doi.org/10.1073/pnas.0906334106
    Citation Count: 296
  • Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells
    2009
    Summary Details
    OPEN
    Title: Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells
    Author(s): Marta Biagioli, Milena Pinto, Daniela Cesselli, Marta Zaninello, Dejan Lazarević, Paola Roncaglia, Roberto Simone, Christina Vlachouli, Charles Plessy, Nicolas Bertin, Antonio Paolo Beltrami, Kazuto Kobayashi, Vittorio Gallo, Claudio Santoro, Isidró Ferrer, Stefano Rivella, Carlo Alberto Beltrami, Piero Carninci, Elio Raviola, Stefano Gustincich
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 106
    Issue #: 36
    Start Page: 15454
    End Page: 15459
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0813216106
    Best OA location URL: http://www.pnas.org/content/106/36/15454.full.pdf
    Citation Count: 260
  • Autonomic function, as self-reported on the SCOPA-autonomic questionnaire, is normal in essential tremor but not in Parkinson's disease
    2012
    Summary Details
    OPEN
    Title: Autonomic function, as self-reported on the SCOPA-autonomic questionnaire, is normal in essential tremor but not in Parkinson's disease
    Author(s): Anne Damian, Charles H. Adler, Joseph G. Hentz, Holly A. Shill, John N. Caviness, Marwan N. Sabbagh, Virgilio Gerald H. Evidente, Thomas G. Beach, Erika Driver‐Dunckley
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 18
    Issue #: 10
    Start Page: 1089
    End Page: 1093
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2012.06.008
    Best OA location URL: https://doi.org/10.1016/j.parkreldis.2012.06.008
    Citation Count: 62
  • Epidemiology and neuropsychiatric manifestations of Young Onset Parkinson's Disease in the United States
    2012
    Summary Details
    OPEN
    Title: Epidemiology and neuropsychiatric manifestations of Young Onset Parkinson's Disease in the United States
    Author(s): Allison W. Willis, Mario Schootman, Nina Kung, Brad A. Racette
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 19
    Issue #: 2
    Start Page: 202
    End Page: 206
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2012.09.014
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3562561
    Citation Count: 46
  • Treatment of myoclonus-dystonia syndrome with tetrabenazine
    2014
    Summary Details
    OPEN
    Title: Treatment of myoclonus-dystonia syndrome with tetrabenazine
    Author(s): Angelo Y. Luciano, Hyder A. Jinnah, Ronald F. Pfeiffer, Daniel Truong, Martha Nance, Mark S. LeDoux
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 20
    Issue #: 12
    Start Page: 1423
    End Page: 1426
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.09.029
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4254189
    Citation Count: 34
  • Changes in the detergent‐insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression
    2016
    Summary Details
    OPEN
    Title: Changes in the detergent‐insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression
    Author(s): Chadwick M. Hales, Eric B. Dammer, Qiudong Deng, Duc M. Duong, Marla Gearing, Juan C. Troncoso, Madhav Thambisetty, James J. Lah, Joshua M. Shulman, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: PROTEOMICS
    Publisher: Wiley
    Vol: 16
    Issue #: 23
    Start Page: 3042
    End Page: 3053
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/pmic.201600057
    Citation Count: 86
  • Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
    2017
    Summary Details
    OPEN
    Title: Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
    Author(s): Dilan Athauda, Kate Maclagan, Simon S. Skene, Martha Bajwa-Joseph, Dawn Letchford, Kashfia Chowdhury, Steve Hibbert, Natalia Budnik, Luca Zampedri, John Dickson, Yazhou Li, Icíar Avilés-Olmos, Thomas T. Warner, Patricia Limousin, Andrew J. Lees, Nigel H. Greig, Susan Tebbs, Thomas Foltynie
    Journal Name: The Lancet
    Publisher: Elsevier BV
    Vol: 390
    Issue #: 10103
    Start Page: 1664
    End Page: 1675
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/s0140-6736(17)31585-4
    Citation Count: 690
  • Sequential Voluntary Cough and Aspiration or Aspiration Risk in Parkinson’s Disease
    2014
    Summary Details
    OPEN
    Title: Sequential Voluntary Cough and Aspiration or Aspiration Risk in Parkinson’s Disease
    Author(s): Karen Wheeler‐Hegland, Michael S. Okun, Michelle S. Troche
    Journal Name: Lung
    Publisher: Springer Science and Business Media LLC
    Vol: 192
    Issue #: 4
    Start Page: 601
    End Page: 608
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00408-014-9584-7
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4740922
    Citation Count: 89
  • Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease
    2018
    Summary Details
    OPEN
    Title: Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease
    Author(s): Madelyn C. Houser, Jianjun Chang, Stewart A. Factor, Eric Molho, Cyrus P. Zabetian, Erin M. Hill‐Burns, Haydeh Payami, Vicki Hertzberg, Malú G. Tansey
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 5
    Start Page: 793
    End Page: 804
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27326
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5992021
    Citation Count: 162
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