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  • 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
    2018
    Summary Details
    RESTRICTED
    Title: 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
    Author(s): Silvia Fanni, Simona Scheggi, Francesca Rossi, Elisabetta Tronci, Francesco Traccis, Roberto Stancampiano, Maria Graziella De Montis, Paola Devoto, Carla Gambarana, Marco Bortolato, Roberto Frau, Manolo Carta
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 121
    Issue #:
    Start Page: 120
    End Page: 130
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2018.09.018
    Best OA location URL:
    Citation Count: 32
  • Animal models of neurodegenerative diseases
    2018
    Summary Details
    RESTRICTED
    Title: Animal models of neurodegenerative diseases
    Author(s): Ted M. Dawson, Todd E. Golde, Clotilde Lagier‐Tourenne
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 21
    Issue #: 10
    Start Page: 1370
    End Page: 1379
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0236-8
    Best OA location URL: https://europepmc.org/articles/pmc6615039?pdf=render
    Citation Count: 374
  • CSF Aβ1–42 level is associated with cognitive decline in early Parkinson’s disease with rapid eye movement sleep behavior disorder
    2018
    Summary Details
    OPEN
    Title: CSF Aβ1–42 level is associated with cognitive decline in early Parkinson’s disease with rapid eye movement sleep behavior disorder
    Author(s): Maowen Ba, Guoping Yu, Min Kong, Hui Liang, Ling Yu
    Journal Name: Translational Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40035-018-0129-5
    Best OA location URL: https://translationalneurodegeneration.biomedcentral.com/track/pdf/10.1186/s40035-018-0129-5
    Citation Count: 11
  • USP 14 inhibition corrects an in vivo model of impaired mitophagy
    2018
    Summary Details
    OPEN
    Title: USP 14 inhibition corrects an in vivo model of impaired mitophagy
    Author(s): Joy Chakraborty, Sophia von Stockum, Elena Marchesan, Federico Caicci, Vanni Ferrari, Aleksandar Raković, Christine Klein, Angelo Antonini, Luigi Bubacco, Elena Ziviani
    Journal Name: EMBO Molecular Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.15252/emmm.201809014
    Best OA location URL: https://doi.org/10.15252/emmm.201809014
    Citation Count: 90
  • Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
    2018
    Summary Details
    OPEN
    Title: Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
    Author(s): Lana M. Chahine, Thomas G. Beach, Nicholas Seedorff, Chelsea Caspell‐Garcia, Christopher S. Coffey, Michael C. Brumm, Charles H. Adler, Geidy E. Serrano, Carly Linder, Sherri Mosovsky, Tatiana Foroud, Holly Riss, Dixie Ecklund, John Seibyl, Danna Jennings, Vanessa Arnedo, Lindsey Riley, Kuldip D. Dave, Brit Mollenhauer
    Journal Name: Journal of Parkinson’s Disease
    Publisher: SAGE Publications
    Vol: 8
    Issue #: 4
    Start Page: 517
    End Page: 527
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181434
    Best OA location URL: http://hdl.handle.net/1805/19746
    Citation Count: 22
  • Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat
    2018
    Summary Details
    OPEN
    Title: Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat
    Author(s): Laura Anselmi, Cecilia Bove, F. Holly Coleman, Kim-Phuong N. Le, Megha Subramanian, Kala Venkiteswaran, Thyagarajan Subramanian, R. Alberto Travagli
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-018-0066-0
    Best OA location URL: https://www.nature.com/articles/s41531-018-0066-0.pdf
    Citation Count: 56
  • Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study
    2018
    Summary Details
    OPEN
    Title: Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study
    Author(s): Rodolfo Savica, Thomas G. Beach, Joseph G. Hentz, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Brittany N. Dugger, Holly A. Shill, Erika Driver‐Dunckley, John N. Caviness, Shyamal H. Mehta, Sandra A. Jacobson, Christine M. Belden, Kathryn Davis, Edward Zamrini, David Shprecher, Charles H. Adler
    Journal Name: Acta Neurologica Scandinavica
    Publisher: Wiley
    Vol: 139
    Issue #: 1
    Start Page: 76
    End Page: 81
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ane.13028
    Best OA location URL: https://doi.org/10.1111/ane.13028
    Citation Count: 42
  • Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease
    2018
    Summary Details
    OPEN
    Title: Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease
    Author(s): Measho Abreha, Eric B. Dammer, Lingyan Ping, Tian Zhang, Duc M. Duong, Marla Gearing, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: PROTEOMICS
    Publisher: Wiley
    Vol: 18
    Issue #: 20
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/pmic.201800108
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6283072
    Citation Count: 63
  • Unraveling connectivity changes due to dopaminergic therapy in chronically treated Parkinson’s disease patients
    2018
    Summary Details
    OPEN
    Title: Unraveling connectivity changes due to dopaminergic therapy in chronically treated Parkinson’s disease patients
    Author(s): Tommaso Ballarini, Filip Růžička, Ondřej Bezdíček, Evžen Růžička, Jan Roth, Arno Villringer, Josef Vymazal, Karsten Mueller, Matthias L. Schroeter, Robert Jech
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-31988-0
    Best OA location URL: https://www.nature.com/articles/s41598-018-31988-0.pdf
    Citation Count: 21
  • Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders
    2018
    Summary Details
    OPEN
    Title: Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders
    Author(s): Rik Ossenkoppele, Gil D. Rabinovici, Ruben Smith, Hanna Cho, Michael Schöll, Olof Strandberg, Sebastian Palmqvist, Niklas Mattsson, Shorena Janelidze, Alexander Santillo, Tomas Ohlsson, Jonas Jögi, Richard Tsai, Renaud La Joie, Joel H. Kramer, Adam L. Boxer, Maria Luisa Gorno‐Tempini, Bruce L. Miller, Jae Yong Choi, Young Hoon Ryu, Chul Hyoung Lyoo, Oskar Hansson
    Journal Name: JAMA
    Publisher: American Medical Association (AMA)
    Vol: 320
    Issue #: 11
    Start Page: 1151
    End Page: 1151
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/jama.2018.12917
    Best OA location URL: https://jamanetwork.com/journals/jama/articlepdf/2702872/jama_ossenkoppele_2018_pc_180007.pdf
    Citation Count: 373
  • β2‐adrenoreceptor medications and risk of Parkinson disease
    2018
    Summary Details
    OPEN
    Title: β2‐adrenoreceptor medications and risk of Parkinson disease
    Author(s): Susan Searles Nielsen, Anat Gross, Alejandra Camacho‐Soto, Allison W. Willis, Brad A. Racette
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 84
    Issue #: 5
    Start Page: 683
    End Page: 693
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.25341
    Best OA location URL:
    Citation Count: 72
  • Insights into the Influence of Specific Splicing Events on the Structural Organization of LRRK2
    2018
    Summary Details
    OPEN
    Title: Insights into the Influence of Specific Splicing Events on the Structural Organization of LRRK2
    Author(s): Dimitriοs Vlachakis, Nikolaos E. Labrou, Costas S. Iliopoulos, John Hardy, Patrick A. Lewis, Hardy J. Rideout, Daniah Trabzuni
    Journal Name: International Journal of Molecular Sciences
    Publisher: MDPI AG
    Vol: 19
    Issue #: 9
    Start Page: 2784
    End Page: 2784
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/ijms19092784
    Best OA location URL: https://www.mdpi.com/1422-0067/19/9/2784/pdf?version=1537093660
    Citation Count: 2
  • Common and rare GCH1 variants are associated with Parkinson's disease
    2018
    Summary Details
    OPEN
    Title: Common and rare GCH1 variants are associated with Parkinson's disease
    Author(s): Uladzislau Rudakou, Bouchra Ouled Amar Bencheikh, Jennifer A. Ruskey, Lynne Krohn, Sandra B. Laurent, Dan Spiegelman, Christopher Liong, Stanley Fahn, Cheryl Waters, Oury Monchi, Edward A. Fon, Yves Dauvilliers, Roy N. Alcalay, Nicolas Dupré, Ziv Gan‐Or
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 73
    Issue #:
    Start Page: 231.e1
    End Page: 231.e6
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2018.09.008
    Best OA location URL:
    Citation Count: 29
  • An mGlu4‐Positive Allosteric Modulator Alleviates Parkinsonism in Primates
    2018
    Summary Details
    RESTRICTED
    Title: An mGlu4‐Positive Allosteric Modulator Alleviates Parkinsonism in Primates
    Author(s): Delphine Charvin, Thérèse Di Paolo, Erwan Bézard, Laurent Grégoire, Akihiro Takano, Guillaume Duvey, Elsa Y. Pioli, Christer Halldin, Rossella Medori, François Conquet
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 10
    Start Page: 1619
    End Page: 1631
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27462
    Best OA location URL:
    Citation Count: 50
  • Detecting Mild Cognitive Deficits in Parkinson's Disease: Comparison of Neuropsychological Tests
    2018
    Summary Details
    RESTRICTED
    Title: Detecting Mild Cognitive Deficits in Parkinson's Disease: Comparison of Neuropsychological Tests
    Author(s): Jeroen Hoogland, Lennard L. van Wanrooij, Judith A. Boel, Jennifer G. Goldman, Glenn T. Stebbins, John C. Dalrymple‐Alford, Connie Marras, Charles H. Adler, Carme Junqué, Kenn Freddy Pedersen, Brit Mollenhauer, Cyrus P. Zabetian, Paul J. Eslinger, Simon Lewis, Ruey‐Meei Wu, Martin Klein, Maria C. Rodríguez‐Oroz, Davide Maria Cammisuli, Paolo Barone, Roberta Biundo, Rob M.A. de Bie, Ben Schmand, Alexander I. Tröster, David J. Burn, Irene Litvan, J. Vincent Filoteo, Gert J. Geurtsen, Daniel Weintraub
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 11
    Start Page: 1750
    End Page: 1759
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.110
    Best OA location URL: https://europepmc.org/articles/pmc6261669?pdf=render
    Citation Count: 45
  • Modeling and prediction of clinical symptom trajectories in Alzheimer’s disease using longitudinal data
    2018
    Summary Details
    OPEN
    Title: Modeling and prediction of clinical symptom trajectories in Alzheimer’s disease using longitudinal data
    Author(s): Nikhil Bhagwat, Joseph D. Viviano, Aristotle N. Voineskos, M. Mallar Chakravarty
    Journal Name: PLOS Computational Biology
    Publisher: Public Library of Science (PLoS)
    Vol: 14
    Issue #: 9
    Start Page: e1006376
    End Page: e1006376
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pcbi.1006376
    Best OA location URL: https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006376&type=printable
    Citation Count: 134
  • Autonomic dysfunction and white matter microstructural changes in drug-naïve patients with Parkinson’s disease
    2018
    Summary Details
    OPEN
    Title: Autonomic dysfunction and white matter microstructural changes in drug-naïve patients with Parkinson’s disease
    Author(s): Amir Ashraf‐Ganjouei, Alireza Majd, Ali Javinani, Mohammad Hadi Aarabi
    Journal Name: PeerJ
    Publisher: PeerJ
    Vol: 6
    Issue #:
    Start Page: e5539
    End Page: e5539
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.7717/peerj.5539
    Best OA location URL: https://peerj.com/articles/5539.pdf
    Citation Count: 18
  • Multi-objective particle swarm optimization for postoperative deep brain stimulation targeting of subthalamic nucleus pathways
    2018
    Summary Details
    OPEN
    Title: Multi-objective particle swarm optimization for postoperative deep brain stimulation targeting of subthalamic nucleus pathways
    Author(s): Edgar Peña, Simeng Zhang, Rémi Patriat, Joshua E. Aman, Jerrold L. Vitek, Noam Harel, Matthew D. Johnson
    Journal Name: Journal of Neural Engineering
    Publisher: IOP Publishing
    Vol: 15
    Issue #: 6
    Start Page: 066020
    End Page: 066020
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1088/1741-2552/aae12f
    Best OA location URL: https://europepmc.org/articles/pmc6424118?pdf=render
    Citation Count: 35
  • Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease
    2018
    Summary Details
    OPEN
    Title: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease
    Author(s): Xianjun Dong, Zhixiang Liao, David Gritsch, Yavor Hadzhiev, Yunfei Bai, Joseph J. Locascio, Boris Guennewig, Ganqiang Liu, Cornelis Blauwendraat, Tao Wang, Charles H. Adler, John C. Hedreen, Richard L. M. Faull, Matthew P. Frosch, Peter T. Nelson, Patrizia Rizzu, Antony A. Cooper, Peter Heutink, Thomas G. Beach, John S. Mattick, Ferenc Müller, Clemens R. Scherzer
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 21
    Issue #: 10
    Start Page: 1482
    End Page: 1492
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0223-0
    Best OA location URL: https://europepmc.org/articles/pmc6334654?pdf=render
    Citation Count: 95
  • Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau
    2018
    Summary Details
    OPEN
    Title: Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau
    Author(s): Urmi Sengupta, Rakez Kayed
    Journal Name: Neuropsychopharmacology
    Publisher: Springer Science and Business Media LLC
    Vol: 44
    Issue #: 1
    Start Page: 222
    End Page: 223
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41386-018-0204-8
    Best OA location URL: https://www.nature.com/articles/s41386-018-0204-8.pdf
    Citation Count: 1
  • Depressive symptoms may increase the risk of the future development of freezing of gait in patients with Parkinson's disease: Findings from a 5-year prospective study
    2018
    Summary Details
    RESTRICTED
    Title: Depressive symptoms may increase the risk of the future development of freezing of gait in patients with Parkinson's disease: Findings from a 5-year prospective study
    Author(s): Talia Herman, Shirley Shema-Shiratzky, Liraz Arie, Nir Giladi, Jeffrey M. Hausdorff
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 60
    Issue #:
    Start Page: 98
    End Page: 104
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.09.013
    Best OA location URL:
    Citation Count: 38
  • Repeated Spiral Drawings in Essential Tremor: a Possible Limb-Based Measure of Motor Learning
    2018
    Summary Details
    RESTRICTED
    Title: Repeated Spiral Drawings in Essential Tremor: a Possible Limb-Based Measure of Motor Learning
    Author(s): Christine Kim, Lan Luo, Qiping Yu, Ana Mirallave, Rachel Saunders‐Pullman, Richard B. Lipton, Elan D. Louis, Seth L. Pullman
    Journal Name: The Cerebellum
    Publisher: Springer Science and Business Media LLC
    Vol: 18
    Issue #: 2
    Start Page: 178
    End Page: 187
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s12311-018-0974-x
    Best OA location URL:
    Citation Count: 5
  • Antidepressant potential of metabotropic glutamate receptor mGlu2 and mGlu3 negative allosteric modulators
    2018
    Summary Details
    OPEN
    Title: Antidepressant potential of metabotropic glutamate receptor mGlu2 and mGlu3 negative allosteric modulators
    Author(s): Max E. Joffe, P. Jeffrey Conn
    Journal Name: Neuropsychopharmacology
    Publisher: Springer Science and Business Media LLC
    Vol: 44
    Issue #: 1
    Start Page: 214
    End Page: 236
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41386-018-0192-8
    Best OA location URL: https://www.nature.com/articles/s41386-018-0192-8.pdf
    Citation Count: 17
  • Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease
    2018
    Summary Details
    OPEN
    Title: Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease
    Author(s): Isabel Ortuño‐Lizarán, Gema Esquiva, Thomas G. Beach, Geidy E. Serrano, Charles H. Adler, Pedro Lax, Nicolás Cuenca
    Journal Name: Acta Neuropathologica Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40478-018-0596-z
    Best OA location URL: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-018-0596-z
    Citation Count: 70
  • Early detection of Parkinson’s disease through patient questionnaire and predictive modelling
    2018
    Summary Details
    OPEN
    Title: Early detection of Parkinson’s disease through patient questionnaire and predictive modelling
    Author(s): R. Prashanth, Sumantra Dutta Roy
    Journal Name: International Journal of Medical Informatics
    Publisher: Elsevier BV
    Vol: 119
    Issue #:
    Start Page: 75
    End Page: 87
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.ijmedinf.2018.09.008
    Best OA location URL: https://arxiv.org/pdf/1810.01855
    Citation Count: 75
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