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  • Intake of antioxidant vitamins and risk of Parkinson's disease
    2016
    OPEN
    Title: Intake of antioxidant vitamins and risk of Parkinson's disease
    Author(s): Katherine C. Hughes, Xiang Gao, Iris Y. Kim, Eric B. Rimm, Molin Wang, Marc G. Weisskopf, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 31
    Issue #: 12
    Start Page: 1909
    End Page: 1914
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26819
    Best OA location URL: https://europepmc.org/articles/pmc5154924?pdf=render
    Citation Count: 99
  • c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson’s Disease
    2016
    RESTRICTED
    Title: c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson’s Disease
    Author(s): Dan Lindholm, Dan Duc Pham, A Cascone, Ove Eriksson, Krister Wennerberg, Märt Saarma
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 8
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2016.00254
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2016.00254/pdf
    Citation Count: 38
  • TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau
    2016
    OPEN
    Title: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau
    Author(s): Maxime W.C. Rousseaux, María de Haro, Cristian A. Lasagna‐Reeves, Antonia De Maio, Jeehye Park, Paymaan Jafar‐Nejad, Ismael Al‐Ramahi, Ajay Sharma, Lauren See, Nan Lü, Luis Vilanova-Velez, Tiemo J. Klisch, Thomas F. Westbrook, Juan C. Troncoso, Juan Botas, Huda Y. Zoghbi
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Vol: 5
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.7554/elife.19809
    Best OA location URL: https://doi.org/10.7554/elife.19809
    Citation Count: 109
  • A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals?
    2016
    OPEN
    Title: A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals?
    Author(s): Laura Wisse, Ana M. Daugherty, Rosanna K. Olsen, David Berron, Valerie A. Carr, Craig E.L. Stark, Robert S.C. Amaral, Katrin Amunts, Jean C. Augustinack, Andrew R. Bender, Jeffrey D. Bernstein, Marina Boccardi, Martina Bocchetta, Alison C. Burggren, M. Mallar Chakravarty, Marie Chupin, Arne D. Ekstrom, Robin de Flores, Ricardo Insausti, Prabesh Kanel, Olga Kedo, Kristen M. Kennedy, Geoffrey A. Kerchner, Karen F. LaRocque, Xiuwen Liu, Anne Maaß, Nikolai Malykhin, Susanne G. Mueller, Noa Ofen, Daniela J. Palombo, Mansi Parekh, John Pluta, Jens C. Pruessner, Naftali Raz, Karen M. Rodrigue, Dorothée Schoemaker, Andrea T. Shafer, Trevor A. Steve, Nanthia Suthana, Lei Wang, Julie L. Winterburn, Michael A. Yassa, Paul A. Yushkevich, Renaud La Joie
    Journal Name: Hippocampus
    Publisher: Wiley
    Vol: 27
    Issue #: 1
    Start Page: 3
    End Page: 11
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/hipo.22671
    Best OA location URL: https://discovery.ucl.ac.uk/1528722/1/Wisse_et_al-2016-Hippocampus.pdf
    Citation Count: 143
  • CSF Biomarkers and Its Associations with 18F-AV133 Cerebral VMAT2 Binding in Parkinson’s Disease—A Preliminary Report
    2016
    OPEN
    Title: CSF Biomarkers and Its Associations with 18F-AV133 Cerebral VMAT2 Binding in Parkinson’s Disease—A Preliminary Report
    Author(s): Rui Gao, Guangjian Zhang, Xueqi Chen, Aimin Yang, Gwenn S. Smith, Dean F. Wong, Yun Zhou
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 11
    Issue #: 10
    Start Page: e0164762
    End Page: e0164762
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0164762
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0164762&type=printable
    Citation Count: 17
  • T2-Imaging Changes in the Nigrosome-1 Relate to Clinical Measures of Parkinson’s Disease
    2016
    OPEN
    Title: T2-Imaging Changes in the Nigrosome-1 Relate to Clinical Measures of Parkinson’s Disease
    Author(s): Katherine Fu, Romil Nathan, Ivo D. Dinov, Junning Li, Arthur W. Toga
    Journal Name: Frontiers in Neurology
    Publisher: Frontiers Media SA
    Vol: 7
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fneur.2016.00174
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fneur.2016.00174/pdf
    Citation Count: 6
  • White matter microstructural characteristics in newly diagnosed Parkinson’s disease: An unbiased whole-brain study
    2016
    OPEN
    Title: White matter microstructural characteristics in newly diagnosed Parkinson’s disease: An unbiased whole-brain study
    Author(s): Ming‐Ching Wen, Hannah S. E. Heng, Samuel Yong Ern Ng, Louis C.S. Tan, Ling Ling Chan, Eng King Tan
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep35601
    Best OA location URL: https://www.nature.com/articles/srep35601.pdf
    Citation Count: 38
  • Is Axonal Degeneration a Key Early Event in Parkinson’s Disease?
    2016
    RESTRICTED
    Title: Is Axonal Degeneration a Key Early Event in Parkinson’s Disease?
    Author(s): Zuzanna Kurowska, Jeffrey H. Kordower, A. Jon Stoessl, Robert E. Burke, Patrik Brundin, Zhenyu Yue, Scott T. Brady, Jeffrey Milbrandt, Bruce D. Trapp, Todd Sherer, Satish Medicetty
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 6
    Issue #: 4
    Start Page: 703
    End Page: 707
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.3233/jpd-160881
    Best OA location URL: http://darchive.mblwhoilibrary.org/bitstreams/2010ffba-e9af-51c2-a5bd-d7afa7449372/download
    Citation Count: 39
  • The Effects of Physical Activity in Parkinson’s Disease: A Review
    2016
    RESTRICTED
    Title: The Effects of Physical Activity in Parkinson’s Disease: A Review
    Author(s): Martine Lauzé, Jean‐François Daneault, Christian Duval
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 6
    Issue #: 4
    Start Page: 685
    End Page: 698
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-160790
    Best OA location URL: https://europepmc.org/articles/pmc5088404?pdf=render
    Citation Count: 138
  • Clinical and demographic characteristics related to onset site and spread of cervical dystonia
    2016
    OPEN
    Title: Clinical and demographic characteristics related to onset site and spread of cervical dystonia
    Author(s): Scott A. Norris, H. A. Jinnah, Alberto J. Espay, Christine Klein, Norbert Brüggemann, Richard L. Barbano, Irene A. Malaty, Ramon L. Rodriguez, Marie Vidailhet, Emmanuel Roze, Stephen G. Reich, Brian D. Berman, Mark S. LeDoux, Sarah Pirio Richardson, Pinky Agarwal, Zoltán Mari, William G. Ondo, Ludy C. Shih, Susan Fox, Alfredo Berardelli, Claudia M. Testa, Florence Ching-Fen Cheng, Daniel Truong, Fatta B. Nahab, Tao Xie, Mark Hallett, Anne Rosén, Laura J. Wright, Joel S. Perlmutter
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 31
    Issue #: 12
    Start Page: 1874
    End Page: 1882
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26817
    Best OA location URL: https://europepmc.org/articles/pmc5154862?pdf=render
    Citation Count: 41
  • Dexmedetomidine for refractory adrenergic crisis in familial dysautonomia
    2016
    OPEN
    Title: Dexmedetomidine for refractory adrenergic crisis in familial dysautonomia
    Author(s): Ryan C. Dillon, Jose‐Alberto Palma, Christy Spalink, Diana Altshuler, Lucy Norcliffe‐Kaufmann, David Fridman, John Papadopoulos, Horacio Kaufmann
    Journal Name: Clinical Autonomic Research
    Publisher: Springer Science and Business Media LLC
    Vol: 27
    Issue #: 1
    Start Page: 7
    End Page: 15
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s10286-016-0383-5
    Best OA location URL: https://europepmc.org/articles/pmc5292083?pdf=render
    Citation Count: 13
  • Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity
    2016
    OPEN
    Title: Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity
    Author(s): J. L. Webb, Auriel A. Willette
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 50
    Issue #:
    Start Page: 39
    End Page: 46
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2016.10.006
    Best OA location URL: https://europepmc.org/articles/pmc5209269?pdf=render
    Citation Count: 11
  • Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression
    2016
    OPEN
    Title: Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression
    Author(s): Chadwick M. Hales, Eric B. Dammer, Qiudong Deng, Duc M. Duong, Marla Gearing, Juan C. Troncoso, Madhav Thambisetty, James J. Lah, Joshua M. Shulman, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: PROTEOMICS
    Publisher: Wiley
    Vol: 16
    Issue #: 23
    Start Page: 3042
    End Page: 3053
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/pmic.201600057
    Best OA location URL: https://europepmc.org/articles/pmc5462625?pdf=render
    Citation Count: 77
  • Dual Tasking for the Differentiation between Depression and Mild Cognitive Impairment
    2016
    OPEN
    Title: Dual Tasking for the Differentiation between Depression and Mild Cognitive Impairment
    Author(s): Florian G. Metzger, Markus A. Hobert, Ann‐Christine Ehlis, Sandra E. Hasmann, Tim Hahn, Gerhard W. Eschweiler, Daniela Berg, Andreas J. Fallgatter, Walter Maetzler
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 8
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2016.00235
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2016.00235/pdf
    Citation Count: 18
  • Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson’s Disease
    2016
    OPEN
    Title: Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson’s Disease
    Author(s): Marta San Luciano, Cuiling Wang, Roberto A. Ortega, Qiping Yu, Sarah Boschung, Jeannie Soto‐Valencia, Susan Bressman, Richard B. Lipton, Seth L. Pullman, Rachel Saunders‐Pullman
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 11
    Issue #: 10
    Start Page: e0162799
    End Page: e0162799
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0162799
    Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0162799&type=printable
    Citation Count: 93
  • mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
    2016
    OPEN
    Title: mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
    Author(s): Claudia Manzoni, Adamantios Mamais, Dorien A. Roosen, Sybille Dihanich, Marc P. M. Soutar, Hélène Plun‐Favreau, Rina Bandopadhyay, John Hardy, Sharon A. Tooze, Mark Cookson, Patrick A. Lewis
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep35106
    Best OA location URL: https://doi.org/10.1038/srep35106
    Citation Count: 72
  • Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s disease
    2016
    RESTRICTED
    Title: Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s disease
    Author(s): Michael M. Lipp, Richard Batycky, Jerome A. Moore, Mika Leinonen, Martin I. Freed
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 8
    Issue #: 360
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aad8858
    Best OA location URL:
    Citation Count: 63
  • Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
    2016
    OPEN
    Title: Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
    Author(s): Steven Lubbe, Valentina Escott‐Price, J. Raphael Gibbs, Mike A. Nalls, José Brás, T. Ryan Price, Aude Nicolas, Iris E. Jansen, Kin Y. Mok, Alan Pittman, James E. Tomkins, Patrick A. Lewis, Alastair Noyce, Suzanne Lesage, Manu Sharma, Elena Schiff, Adam P. Levine, Alexis Brice, Thomas Gasser, John Hardy, Peter Heutink, Nicholas Wood, Andrew Singleton, Nigel Williams, Huw R. Morris
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol:
    Issue #:
    Start Page: ddw348
    End Page: ddw348
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/hmg/ddw348
    Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/24/5483/10408585/ddw348.pdf
    Citation Count: 49
  • Machine Learning Interface for Medical Image Analysis
    2016
    OPEN
    Title: Machine Learning Interface for Medical Image Analysis
    Author(s): Yi Cheng Zhang, Alexander C. Kagen
    Journal Name: Journal of Digital Imaging
    Publisher: Springer Science and Business Media LLC
    Vol: 30
    Issue #: 5
    Start Page: 615
    End Page: 621
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s10278-016-9910-0
    Best OA location URL: https://europepmc.org/articles/pmc5603426?pdf=render
    Citation Count: 58
  • Neuropsychological impairment in prodromal Parkinson's disease
    2016
    RESTRICTED
    Title: Neuropsychological impairment in prodromal Parkinson's disease
    Author(s): Christoph Pausch, Robert Schomburg, Stefan Wagenpfeil, Frank A. Wollenweber, Caroline Bayer, Klaus Faßbender, Stefanie Behnke
    Journal Name: Journal of the Neurological Sciences
    Publisher: Elsevier BV
    Vol: 371
    Issue #:
    Start Page: 117
    End Page: 120
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.jns.2016.10.007
    Best OA location URL:
    Citation Count: 14
  • Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
    2016
    OPEN
    Title: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
    Author(s): Mariet Allen, Minerva M. Carrasquillo, Cory C. Funk, Ben Heavner, Fanggeng Zou, Curtis Younkin, Jeremy D. Burgess, High Seng Chai, Julia E. Crook, James A. Eddy, Hong‐Dong Li, Benjamin A. Logsdon, Mette A. Peters, Kristen K. Dang, Xue Wang, Daniel Serie, Chen Wang, Thuy Nguyen, Sarah Lincoln, Kimberly G. Malphrus, Gina Bisceglio, Li Ma, Todd E. Golde, Lara M. Mangravite, Yan W. Asmann, Nathan D. Price, Peter St George–Hyslop, Neill R. Graff‐Radford, Dennis W. Dickson, Stéphanie Debette, Nilüfer Ertekin‐Taner
    Journal Name: Scientific Data
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/sdata.2016.89
    Best OA location URL: https://www.nature.com/articles/sdata201689.pdf
    Citation Count: 393
  • Impaired contrast sensitivity is associated with more severe cognitive impairment in Parkinson disease
    2016
    OPEN
    Title: Impaired contrast sensitivity is associated with more severe cognitive impairment in Parkinson disease
    Author(s): Andrew Ridder, Martijn L.T.M. Müller, Vikas Kotagal, Kirk A. Frey, Roger L. Albin, Nicolaas I. Bohnen
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 34
    Issue #:
    Start Page: 15
    End Page: 19
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.10.006
    Best OA location URL: https://europepmc.org/articles/pmc5222688?pdf=render
    Citation Count: 32
  • N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase
    2016
    OPEN
    Title: N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase
    Author(s): Jeremy S. Francis, Ireneusz Wojtas, Vladimir Markov, Steven J. Gray, Thomas J. McCown, R. Jude Samulski, Larissa T. Bilaniuk, Dah-Jyuu Wang, Darryl C. De Vivo, Christopher G. Janson, Paola Leone
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 96
    Issue #:
    Start Page: 323
    End Page: 334
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2016.10.001
    Best OA location URL: https://europepmc.org/articles/pmc5102763?pdf=render
    Citation Count: 32
  • Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
    2016
    OPEN
    Title: Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
    Author(s): Shu G. Chen, Vilius Stribinskis, Madhavi J. Rane, Donald R. Demuth, Evelyne Gozal, Andrew M. Roberts, Rekha Jagadapillai, Ruolan Liu, Kyonghwan Choe, Bhooma Shivakumar, Francheska Son, Shufang Jin, Richard A. Kerber, Anthony Adame, Eliezer Masliah, Robert P. Friedland
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep34477
    Best OA location URL: https://www.nature.com/articles/srep34477.pdf
    Citation Count: 366
  • Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration
    2016
    OPEN
    Title: Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration
    Author(s): Mónica Sánchez-Contreras, Michael G. Heckman, Paweł Tacik, Nancy N. Diehl, Patricia E. Brown, Alexandra I. Soto‐Ortolaza, Elizabeth Christopher, Ronald L. Walton, Owen A. Ross, Lawrence I. Golbe, Neill R. Graff‐Radford, Zbigniew K. Wszołek, Dennis W. Dickson, Rosa Rademakers
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 32
    Issue #: 1
    Start Page: 115
    End Page: 123
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26815
    Best OA location URL: https://europepmc.org/articles/pmc5269612?pdf=render
    Citation Count: 53
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