6326 - 6350 of 8823 Results
Title
Year
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OPENTitle: Structural Characterization of LRRK2 InhibitorsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 58Issue #: 9Start Page: 3751End Page: 3756Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm5018779Best OA location URL: https://research.rug.nl/en/publications/5c2dfd00-1285-4fd7-a819-6b338c56d5a8Citation Count: 38
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OPENTitle: Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's diseaseJournal Name: Stem Cell ResearchPublisher: Elsevier BVVol: 28Issue #:Start Page: 161End Page: 164Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.scr.2018.02.015Best OA location URL: https://doi.org/10.1016/j.scr.2018.02.015Citation Count: 9
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OPENTitle: Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and ToxicityJournal Name: ACS Chemical BiologyPublisher: American Chemical Society (ACS)Vol: 11Issue #: 4Start Page: 931End Page: 942Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschembio.5b01042Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6300141Citation Count: 31
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OPENTitle: Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonistsJournal Name: British Journal of PharmacologyPublisher: WileyVol: 175Issue #: 5Start Page: 782End Page: 796Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/bph.14123Best OA location URL: https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bph.14123Citation Count: 20
- The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR22016OPENTitle: The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR2Journal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 8Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2015.00089Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2015.00089/pdfCitation Count: 59
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RESTRICTEDTitle: Design, synthesis, and evaluation of a selective chemosensor for leucine-rich repeat kinase 2Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 24Issue #: 24Start Page: 5648End Page: 5651Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2014.10.079Citation Count: 8
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OPENTitle: Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathiesJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 28Issue #: 4Start Page: 548End Page: 560Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddy365Best OA location URL: https://academic.oup.com/hmg/article-pdf/28/4/548/27636558/ddy365.pdfCitation Count: 65
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RESTRICTEDTitle: The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid FormationJournal Name: Journal of the American Chemical SocietyPublisher: American Chemical Society (ACS)Vol: 136Issue #: 10Start Page: 3859End Page: 3868Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/ja411577tCitation Count: 238
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OPENTitle: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesisJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 6Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.31012Best OA location URL: https://doi.org/10.7554/elife.31012Citation Count: 461
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OPENTitle: Comparison of voluntary and reflex cough effectiveness in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 20Issue #: 11Start Page: 1226End Page: 1230Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.09.010Best OA location URL: http://doi.org/10.1016/j.parkreldis.2014.09.010Citation Count: 46
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OPENTitle: Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in ratsJournal Name: NeurosciencePublisher: Elsevier BVVol: 318Issue #:Start Page: 157End Page: 165Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuroscience.2016.01.020Best OA location URL: http://doi.org/10.1016/j.neuroscience.2016.01.020Citation Count: 93
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OPENTitle: Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and InternalizationJournal Name: Journal of Biological ChemistryPublisher: Elsevier BVVol: 291Issue #: 9Start Page: 4374End Page: 4385Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1074/jbc.m115.705095Best OA location URL: http://www.jbc.org/article/S0021925820435859/pdfCitation Count: 145
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RESTRICTEDTitle: Erythropoietin and small molecule agonists of the tissue-protective erythropoietin receptor increase FXN expression in neuronal cells in vitro and in Fxn-deficient KIKO mice in vivoJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 123Issue #:Start Page: 34End Page: 45Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2017.05.011Citation Count: 11
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OPENTitle: CoREST Complex-Selective Histone Deacetylase Inhibitors Show Prosynaptic Effects and an Improved Safety Profile To Enable Treatment of SynaptopathiesJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 10Issue #: 3Start Page: 1729End Page: 1743Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00620Citation Count: 42
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OPENTitle: Practical Application of DaTQUANT with Optimal Threshold for Diagnostic Accuracy of Dopamine Transporter SPECTJournal Name: TomographyPublisher: MDPI AGVol: 7Issue #: 4Start Page: 980End Page: 989Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/tomography7040081Best OA location URL: https://www.mdpi.com/2379-139X/7/4/81/pdf?version=1640054033Citation Count: 20
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OPENTitle: Safety of AADC Gene Therapy for Moderately Advanced Parkinson DiseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 98Issue #: 1Start Page: e40End Page: e50Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1212/wnl.0000000000012952Best OA location URL: https://escholarship.org/uc/item/9jh0j4gbCitation Count: 77
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OPENTitle: Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegenerationJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 144Issue #: 12Start Page: 3674End Page: 3691Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awab356Best OA location URL: https://academic.oup.com/brain/article-pdf/144/12/3674/42004692/awab356.pdfCitation Count: 26
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OPENTitle: Trajectory Analysis of Orthostatic Hypotension in Parkinson’s Disease: Results From Parkinson’s Progression Markers Initiative CohortJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 13Issue #:Start Page: 762759End Page: 762759Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2021.762759Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2021.762759/pdfCitation Count: 10
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OPENTitle: NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome ActivationJournal Name: International Journal of InflammationPublisher: WileyVol: 2022Issue #:Start Page: 1End Page: 12Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2022/2337363Best OA location URL: https://downloads.hindawi.com/journals/iji/2022/2337363.pdfCitation Count: 11
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OPENTitle: Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson’s diseaseJournal Name: Molecular Therapy - Nucleic AcidsPublisher: Elsevier BVVol: 28Issue #:Start Page: 1End Page: 15Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.omtn.2022.02.007Best OA location URL: https://doi.org/10.1016/j.omtn.2022.02.007Citation Count: 23
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OPENTitle: Multivariate genomic and transcriptomic determinants of imaging-derived personalized therapeutic needs in Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 12Issue #: 1Start Page: 5483End Page: 5483Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-022-09506-0Best OA location URL: https://www.nature.com/articles/s41598-022-09506-0.pdfCitation Count: 7
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OPENTitle: Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal MitochondriaJournal Name: Frontiers in Cellular NeurosciencePublisher: Frontiers Media SAVol: 16Issue #:Start Page: 852245End Page: 852245Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fncel.2022.852245Best OA location URL: https://doi.org/10.3389/fncel.2022.852245Citation Count: 6
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OPENTitle: Disease-Modifying Antirheumatic Drugs and Risk of Parkinson DiseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 98Issue #: 12Start Page: e1273End Page: e1281Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000013303Best OA location URL: https://n.neurology.org/content/neurology/98/12/e1273.full.pdfCitation Count: 23
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OPENTitle: Psychometric Properties of Clinical Indicators for Identification and Management of Advanced Parkinson’s Disease: Real-World Evidence From G7 CountriesJournal Name: Neurology and TherapyPublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page: 303End Page: 318Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1007/s40120-021-00313-9Best OA location URL: https://link.springer.com/content/pdf/10.1007/s40120-021-00313-9.pdfCitation Count: 11
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OPENTitle: Real-World Adherence to Tetrabenazine or Deutetrabenazine Among Patients With Huntington’s Disease: A Retrospective Database AnalysisJournal Name: Neurology and TherapyPublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page: 435End Page: 448Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1007/s40120-021-00309-5Best OA location URL: https://link.springer.com/content/pdf/10.1007/s40120-021-00309-5.pdfCitation Count: 14