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  • Gene therapy device-based delivery of progranulin, prosaposin, and GDNF as a combined precision and neurorestorative therapy in the rat 6-OHDA model of parkinsonism
    2025
    Summary Details
    OPEN
    Title: Gene therapy device-based delivery of progranulin, prosaposin, and GDNF as a combined precision and neurorestorative therapy in the rat 6-OHDA model of parkinsonism
    Author(s): Chiara Bertasini, Marco Rossini, Jacopo Grisotto, Dwaine F. Emerich, Matteo Brunelli, Serena Pedron, Cristina Parrado‐Fernández, Lars U. Wahlberg, Johan Lundkvist, Giovanna Paolone
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 395
    Issue #:
    Start Page: 115474
    End Page: 115474
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2025.115474
    Best OA location URL: https://doi.org/10.1016/j.expneurol.2025.115474
    Citation Count: 0
  • GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
    2025
    Summary Details
    OPEN
    Title: GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
    Author(s): Erin C. Bogacki, Gustavo Morrone Parfitt, A. B. da Cunha, G Longmore, Selina Wray, Patrick A. Lewis, Susanne Herbst
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 11
    Issue #: 51
    Start Page: eadv1434
    End Page: eadv1434
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.adv1434
    Best OA location URL: https://doi.org/10.1126/sciadv.adv1434
    Citation Count: 7
  • Deep brain stimulation of the substantia nigra for freezing of gait in Parkinson's disease: is it about stimulation frequency?
    2018
    Summary Details
    RESTRICTED
    Title: Deep brain stimulation of the substantia nigra for freezing of gait in Parkinson's disease: is it about stimulation frequency?
    Author(s): Daniel Weiß, Luka Milosevic, Alireza Gharabaghi
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 63
    Issue #:
    Start Page: 229
    End Page: 230
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.12.010
    Citation Count: 16
  • An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Aß42 and an APOE ε4 allele
    2019
    Summary Details
    OPEN
    Title: An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Aß42 and an APOE ε4 allele
    Author(s): Marian Shahid, Jeehyun Kim, Katherine Leaver, Taylor R. Hendershott, Delphine Zhu, Brenna Cholerton, Victor W. Henderson, Lü Tian, Kathleen L. Poston
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 127
    Issue #:
    Start Page: 278
    End Page: 286
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2019.02.023
    Best OA location URL: https://doaj.org/article/6a674f9f412742f7840d1c3d8f970659
    Citation Count: 34
  • Altered reward-related neural responses in non-manifesting carriers of the Parkinson disease related LRRK2 mutation
    2018
    Summary Details
    RESTRICTED
    Title: Altered reward-related neural responses in non-manifesting carriers of the Parkinson disease related LRRK2 mutation
    Author(s): Avner Thaler, Tal Gonen, Anat Mirelman, Rick C. Helmich, Tanya Gurevich, Avi Orr‐Urtreger, Bastiaan R. Bloem, Nir Giladi, Talma Hendler
    Journal Name: Brain Imaging and Behavior
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 4
    Start Page: 1009
    End Page: 1020
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s11682-018-9920-2
    Citation Count: 16
  • The UF Deep Brain Stimulation Cognitive Rating Scale (DBS-CRS): Clinical Decision Making, Validity, and Outcomes
    2020
    Summary Details
    OPEN
    Title: The UF Deep Brain Stimulation Cognitive Rating Scale (DBS-CRS): Clinical Decision Making, Validity, and Outcomes
    Author(s): Lauren Kenney, Brittany Rohl, Francesca V. Lopez, Jacob Lafo, Charles E. Jacobson, Michael S. Okun, Kelly D. Foote, Dawn Bowers
    Journal Name: Frontiers in Human Neuroscience
    Publisher: Frontiers Media SA
    Vol: 14
    Issue #:
    Start Page: 578216
    End Page: 578216
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnhum.2020.578216
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnhum.2020.578216/pdf
    Citation Count: 8
  • Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations
    2020
    Summary Details
    OPEN
    Title: Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations
    Author(s): Bramsh Q. Chandio, Shannon L. Risacher, Franco Pestilli, Daniel Bullock, Fang‐Cheng Yeh, Serge Koudoro, Ariel Rokem, Jaroslaw Harezlak, Eleftherios Garyfallidis
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page: 17149
    End Page: 17149
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-020-74054-4
    Best OA location URL: https://www.nature.com/articles/s41598-020-74054-4.pdf
    Citation Count: 134
  • A Survey of Rare Epigenetic Variation in 23,116 Human Genomes Identifies Disease-Relevant Epivariations and CGG Expansions
    2020
    Summary Details
    OPEN
    Title: A Survey of Rare Epigenetic Variation in 23,116 Human Genomes Identifies Disease-Relevant Epivariations and CGG Expansions
    Author(s): Paras Garg, Bharati Jadhav, Oscar L. Rodriguez, Nihir Patel, Alejandro Martin-Trujillo, Miten Jain, Sofie Metsu, Hugh E. Olsen, Benedict Paten, Beate Ritz, R. Frank Kooy, Jozef Gécz, Andrew J. Sharp
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Vol: 107
    Issue #: 4
    Start Page: 654
    End Page: 669
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2020.08.019
    Best OA location URL: http://www.cell.com/article/S0002929720302883/pdf
    Citation Count: 65
  • In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease
    2020
    Summary Details
    OPEN
    Title: In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease
    Author(s): Lana M. Chahine, Thomas G. Beach, Michael C. Brumm, Charles H. Adler, Christopher S. Coffey, Sherri Mosovsky, Chelsea Caspell‐Garcia, Geidy E. Serrano, David G. Muñoz, Charles L. White, John F. Crary, Danna Jennings, Peggy Taylor, Tatiana Foroud, Vanessa Arnedo, Catherine Kopil, Lindsey Riley, Kuldip D. Dave, Brit Mollenhauer, for the Systemic Synuclein Sampling Study
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 95
    Issue #: 9
    Start Page: e1267
    End Page: e1284
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000010404
    Best OA location URL: https://n.neurology.org/content/neurology/95/9/e1267.full.pdf
    Citation Count: 149
  • A blinded, controlled trial of objective measurement in Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: A blinded, controlled trial of objective measurement in Parkinson’s disease
    Author(s): Holly Woodrow, Malcolm Horne, Chathurini V. Fernando, Katya Kotschet, Treat to Target Study Group, Arup Bhattacharya, Richard Blazé, Andrew Roy Charmley, Belinda Cruse, Stephen Duma, Andrew Evans, Mina Ghaly, Blake F. Giarola, Amy J. Halliday, Thomas Kimber, Anand Kumar, Alexander Lehn, Kate Lilley, Andrew Ma, Neil Mahant, Salar McModie, Manju Perera, Huiliang Melissa Tang, John W. Tillett, Stephen Tisch, Antony Winkel, Christine Wools
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page: 35
    End Page: 35
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-020-00136-9
    Best OA location URL: https://www.nature.com/articles/s41531-020-00136-9.pdf
    Citation Count: 31
  • Case Report: Globus Pallidus Internus (GPi) Deep Brain Stimulation Induced Keyboard Typing Dysfunction
    2020
    Summary Details
    OPEN
    Title: Case Report: Globus Pallidus Internus (GPi) Deep Brain Stimulation Induced Keyboard Typing Dysfunction
    Author(s): Joshua K. Wong, Melissa J. Armstrong, Leonardo Almeida, Aparna Wagle Shukla, Addie Patterson, Michael S. Okun, Irene A. Malaty
    Journal Name: Frontiers in Human Neuroscience
    Publisher: Frontiers Media SA
    Vol: 14
    Issue #:
    Start Page: 583441
    End Page: 583441
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnhum.2020.583441
    Best OA location URL: https://doi.org/10.3389/fnhum.2020.583441
    Citation Count: 6
  • Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
    2020
    Summary Details
    OPEN
    Title: Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
    Author(s): Elisabeth H. Thijssen, Renaud La Joie, Amy Wolf, Amelia Strom, Ping Wang, Leonardo Iaccarino, Viktoriya Bourakova, Yann Cobigo, Hilary W. Heuer, Salvatore Spina, Lawren VandeVrede, Xiyun Chai, Nicholas K. Proctor, David Airey, Sergey Shcherbinin, Cynthia Evans, John R. Sims, Henrik Zetterberg, Kaj Blennow, Anna M. Karydas, Charlotte E. Teunissen, Joel H. Kramer, Lea T. Grinberg, William W. Seeley, Howie Rosen, Bradley F. Boeve, Bruce L. Miller, Gil D. Rabinovici, Jeffrey L. Dage, Julio C. Rojas, Adam L. Boxer
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 26
    Issue #: 3
    Start Page: 387
    End Page: 397
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41591-020-0762-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7101073
    Citation Count: 786
  • Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
    2020
    Summary Details
    OPEN
    Title: Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
    Author(s): Patrick L. Heilman, Ernest W. Wang, Mechelle M. Lewis, Stanisław Krzyżanowski, Colt Capan, Amanda R. Burmeister, Guangwei Du, Martha L. Escobar Galvis, Patrik Brundin, Xuemei Huang, Lena Brundin
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 35
    Issue #: 11
    Start Page: 2028
    End Page: 2037
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.28202
    Best OA location URL: https://movementdisorders.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28202
    Citation Count: 121
  • Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells
    2020
    Summary Details
    OPEN
    Title: Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells
    Author(s): Souvarish Sarkar, Eric B. Dammer, Emir Malovic, Abby L. Olsen, Syed Ali Raza, Tianwen Gao, Hailian Xiao, Danielle Oliver, Duc M. Duong, Valerie Joers, Nicholas T. Seyfried, Meixiang Huang, Thomas Kukar, Malú G. Tansey, Anumantha G. Kanthasamy, Srikant Rangaraju
    Journal Name: Frontiers in Immunology
    Publisher: Frontiers Media SA
    Vol: 11
    Issue #:
    Start Page: 33
    End Page: 33
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fimmu.2020.00033
    Best OA location URL: https://doi.org/10.3389/fimmu.2020.00033
    Citation Count: 86
  • AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer’s drug discovery
    2021
    Summary Details
    OPEN
    Title: AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer’s drug discovery
    Author(s): Yadi Zhou, Jiansong Fang, Lynn M. Bekris, Young Heon Kim, Andrew A. Pieper, James B. Leverenz, Jeffrey L. Cummings, Feixiong Cheng
    Journal Name: Alzheimer's Research & Therapy
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 1
    Start Page: 24
    End Page: 24
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13195-020-00760-w
    Best OA location URL: https://alzres.biomedcentral.com/track/pdf/10.1186/s13195-020-00760-w
    Citation Count: 85
  • Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases
    2021
    Summary Details
    OPEN
    Title: Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases
    Author(s): Virginia De Cesare, Daniel Carbajo, Peter D. Mabbitt, Adam J. Fletcher, Mathieu Soetens, Odetta Antico, Nicola T. Wood, Satpal Virdee
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 118
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2006947118
    Best OA location URL: https://www.pnas.org/doi/full/10.1073/pnas.2006947118
    Citation Count: 86
  • Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo
    2020
    Summary Details
    OPEN
    Title: Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo
    Author(s): Benjamin M. Hiller, David J. Marmion, Rachel M. Gross, Cayla A. Thompson, Carrie A. Chavez, Patrik Brundin, Dustin R. Wakeman, Christopher W. McMahon, Jeffrey H. Kordower
    Journal Name: Stem Cells Translational Medicine
    Publisher: Oxford University Press (OUP)
    Vol: 10
    Issue #: 2
    Start Page: 278
    End Page: 290
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/sctm.20-0014
    Best OA location URL: https://stemcellsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/sctm.20-0014
    Citation Count: 22
  • APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease
    2021
    Summary Details
    OPEN
    Title: APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease
    Author(s): Jon-Anders Tunold, Hanneke Geut, Annemieke J.M. Rozemüller, Sandra Pilar Henriksen, Mathias Toft, Wilma D. J. van de Berg, Lasse Pihlstrøm
    Journal Name: Frontiers in Neurology
    Publisher: Frontiers Media SA
    Vol: 12
    Issue #:
    Start Page: 631145
    End Page: 631145
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fneur.2021.631145
    Best OA location URL: https://doi.org/10.3389/fneur.2021.631145
    Citation Count: 48
  • Differential blood DNA methylation across Lewy body dementias
    2021
    Summary Details
    OPEN
    Title: Differential blood DNA methylation across Lewy body dementias
    Author(s): Chanond A. Nasamran, Anubhav Nikunj Singh Sachan, Jennifer Mott, Yuliya I. Kuras, Clemens R. Scherzer, Harvard Biomarkers Study, Eugenia Ricciardelli, Kristen Jepsen, Steven D. Edland, Kathleen M. Fisch, Paula Desplats
    Journal Name: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
    Publisher: Wiley
    Vol: 13
    Issue #: 1
    Start Page: e12156
    End Page: e12156
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/dad2.12156
    Best OA location URL: https://escholarship.org/uc/item/0rj4j3cb
    Citation Count: 11
  • Probable REM sleep behavior disorder is associated with longitudinal cortical thinning in Parkinson’s disease
    2021
    Summary Details
    OPEN
    Title: Probable REM sleep behavior disorder is associated with longitudinal cortical thinning in Parkinson’s disease
    Author(s): Eun Jin Yoon, Oury Monchi
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page: 19
    End Page: 19
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-021-00164-z
    Best OA location URL: https://www.nature.com/articles/s41531-021-00164-z.pdf
    Citation Count: 29
  • Thalamic morphology predicts the onset of freezing of gait in Parkinson’s disease
    2021
    Summary Details
    OPEN
    Title: Thalamic morphology predicts the onset of freezing of gait in Parkinson’s disease
    Author(s): Nicholas D’Cruz, Griet Vervoort, Sima Chalavi, Bauke W. Dijkstra, Moran Gilat, Alice Nieuwboer
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page: 20
    End Page: 20
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-021-00163-0
    Best OA location URL: https://www.nature.com/articles/s41531-021-00163-0.pdf
    Citation Count: 37
  • Validation of a Parkinson Disease Predictive Model in a Population-Based Study
    2020
    Summary Details
    OPEN
    Title: Validation of a Parkinson Disease Predictive Model in a Population-Based Study
    Author(s): Irene Faust, Brad A. Racette, Susan Searles Nielsen
    Journal Name: Parkinson's Disease
    Publisher: Wiley
    Vol: 2020
    Issue #:
    Start Page: 1
    End Page: 7
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1155/2020/2857608
    Best OA location URL: https://downloads.hindawi.com/journals/pd/2020/2857608.pdf
    Citation Count: 10
  • Serum FGF-21, GDF-15, and blood mtDNA copy number are not biomarkers of Parkinson disease
    2020
    Summary Details
    OPEN
    Title: Serum FGF-21, GDF-15, and blood mtDNA copy number are not biomarkers of Parkinson disease
    Author(s): Ryan L. Davis, Siew L. Wong, Phillippa J. Carling, Thomas Payne, Carolyn M. Sue, Oliver Bandmann
    Journal Name: Neurology Clinical Practice
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 10
    Issue #: 1
    Start Page: 40
    End Page: 46
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/cpj.0000000000000702
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7057070
    Citation Count: 32
  • Symptom burden among individuals with Parkinson disease
    2020
    Summary Details
    OPEN
    Title: Symptom burden among individuals with Parkinson disease
    Author(s): Christopher G. Tarolli, Grace A. Zimmerman, Peggy Auinger, Scott McIntosh, Robert Horowitz, Benzi M. Kluger, E. Ray Dorsey, Robert G. Holloway
    Journal Name: Neurology Clinical Practice
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 10
    Issue #: 1
    Start Page: 65
    End Page: 72
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/cpj.0000000000000746
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7057075
    Citation Count: 49
  • Exercise Reverses Dysregulation of T-Cell-Related Function in Blood Leukocytes of Patients With Parkinson's Disease
    2020
    Summary Details
    OPEN
    Title: Exercise Reverses Dysregulation of T-Cell-Related Function in Blood Leukocytes of Patients With Parkinson's Disease
    Author(s): Yong Hu, Kunshan Zhang, Tianyu Zhang, Junbang Wang, Fei Chen, Wenting Qin, Weifang Tong, Qiang Guan, Yijing He, Yulin Ge, Xiaoyu Chen, Un Jung Kang, Yi Sun, Siguang Li, Lingjing Jin
    Journal Name: Frontiers in Neurology
    Publisher: Frontiers Media SA
    Vol: 10
    Issue #:
    Start Page: 1389
    End Page: 1389
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fneur.2019.01389
    Best OA location URL: https://doi.org/10.3389/fneur.2019.01389
    Citation Count: 10
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