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  • Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells
    2017
    Summary Details
    OPEN
    Title: Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells
    Author(s): Kenneth Thirstrup, Justus C. Dächsel, Felix Oppermann, D.S. Williamson, Garrick P. Smith, Karina Fog, Kenneth Vielsted Christensen
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page: 10300
    End Page: 10300
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-017-10501-z
    Best OA location URL: https://www.nature.com/articles/s41598-017-10501-z.pdf
    Citation Count: 105
  • Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
    2017
    Summary Details
    OPEN
    Title: Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
    Author(s): Nour K. Majbour, Davide Chiasserini, Nishant N. Vaikath, Paolo Eusebi, Takahiko Tokuda, Wilma D. J. van de Berg, Lucilla Parnetti, Paolo Calabresi, Omar M. A. El‐Agnaf
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page: 40263
    End Page: 40263
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep40263
    Best OA location URL: https://www.nature.com/articles/srep40263.pdf
    Citation Count: 57
  • Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na+/K+ ATPase Activity in Dendritic Cells
    2017
    Summary Details
    OPEN
    Title: Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na+/K+ ATPase Activity in Dendritic Cells
    Author(s): Zohreh Hosseinzadeh, Yogesh Singh, Derya R. Shimshek, Herman van der Putten, Carsten A. Wagner, Florian Läng
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page: 41117
    End Page: 41117
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep41117
    Best OA location URL: https://www.nature.com/articles/srep41117.pdf
    Citation Count: 8
  • CNTRICS Imaging Biomarkers Final Task Selection: Long-Term Memory and Reinforcement Learning
    2011
    Summary Details
    OPEN
    Title: CNTRICS Imaging Biomarkers Final Task Selection: Long-Term Memory and Reinforcement Learning
    Author(s): J. Daniel Ragland, Neal J. Cohen, Roshan Cools, Megan Frank, Deborah E. Hannula, Charan Ranganath
    Journal Name: Schizophrenia Bulletin
    Publisher: Oxford University Press (OUP)
    Vol: 38
    Issue #: 1
    Start Page: 62
    End Page: 72
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/schbul/sbr168
    Best OA location URL: https://academic.oup.com/schizophreniabulletin/article-pdf/38/1/62/5351297/sbr168.pdf
    Citation Count: 28
  • Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
    2016
    Summary Details
    OPEN
    Title: Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
    Author(s): Shu G. Chen, Vilius Stribinskis, Madhavi J. Rane, Donald R. Demuth, Evelyne Gozal, Andrew M. Roberts, Rekha Jagadapillai, Ruolan Liu, Kyonghwan Choe, Bhooma Shivakumar, Francheska Son, Shunying Jin, Richard A. Kerber, Anthony Adame, Eliezer Masliah, Robert P. Friedland
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page: 34477
    End Page: 34477
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep34477
    Best OA location URL: https://www.nature.com/articles/srep34477.pdf
    Citation Count: 455
  • Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery
    2016
    Summary Details
    OPEN
    Title: Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery
    Author(s): Niyanta Kumar, Mohan Gautam, Jeffrey J. Lochhead, Daniel J. Wolak, Vamsi Krishna Ithapu, Vikas Singh, Robert G. Thorne
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page: 31732
    End Page: 31732
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep31732
    Best OA location URL: https://www.nature.com/articles/srep31732.pdf
    Citation Count: 61
  • Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
    2013
    Summary Details
    OPEN
    Title: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
    Author(s): Carmen Noelker, Lydie Morel, Thomas Lescot, Anke Osterloh, Daniel Alvarez‐Fischer, Minka Breloer, Carmen Henze, Candan Depboylu, Delphine Skrzydelski, Patrick P. Michel, Richard C. Dodel, Lixia Lü, Étienne C. Hirsch, Stéphane Hunot, Andréas Hartmann
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page: 1393
    End Page: 1393
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/srep01393
    Best OA location URL: https://www.nature.com/articles/srep01393.pdf
    Citation Count: 162
  • LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts
    2016
    Summary Details
    OPEN
    Title: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts
    Author(s): Tomoki Kuwahara, Keiichi Inoue, Vivette D. D’Agati, Tetta Fujimoto, Tomoya Eguchi, Shamol Saha, Benjamin Wolozin, Takeshi Iwatsubo, Asa Abeliovich
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page: 29945
    End Page: 29945
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep29945
    Best OA location URL: https://www.nature.com/articles/srep29945.pdf
    Citation Count: 133
  • Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
    2016
    Summary Details
    OPEN
    Title: Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
    Author(s): Maritza Oñate, Alejandra Catenaccio, Gabriela Martínez, Donna Armentano, Geoffrey Parsons, Bredford Kerr, Claudio Hetz, Felipe A. Court
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page: 21709
    End Page: 21709
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep21709
    Best OA location URL: https://www.nature.com/articles/srep21709.pdf
    Citation Count: 100
  • Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients
    2016
    Summary Details
    OPEN
    Title: Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients
    Author(s): Yoshiro Saito, Yoko Ogawa, Akihiro Matsumura, Kazumasa Saigoh, Sayoko Itoh, Kenta Sutou, M. Kobayashi, Yuichiro Mita, Mototada Shichiri, Shin Hisahara, Yasuo Hara, Harutoshi Fujimura, Hiroyuki Takamatsu, Yoshihisa Hagihara, Yasukazu Yoshida, Takao Hamakubo, Susumu Kusunoki, Shun Shimohama, Noriko Noguchi
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page: 30793
    End Page: 30793
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep30793
    Best OA location URL: https://www.nature.com/articles/srep30793.pdf
    Citation Count: 40
  • Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling
    2015
    Summary Details
    OPEN
    Title: Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling
    Author(s): Wei-Zheng Zeng, Di-Shi Liu, Lu Liu, Liang She, Long‐Jun Wu, Tian-Le Xu
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 5
    Issue #: 1
    Start Page: 14125
    End Page: 14125
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep14125
    Best OA location URL: https://www.nature.com/articles/srep14125.pdf
    Citation Count: 45
  • n-3 PUFA supplementation benefits microglial responses to myelin pathology
    2014
    Summary Details
    OPEN
    Title: n-3 PUFA supplementation benefits microglial responses to myelin pathology
    Author(s): Songela Chen, Haiyue Zhang, Hongjian Pu, Guohua Wang, Wenjin Li, Rehana K. Leak, Jun Chen, Anthony K. F. Liou, Xiaoming Hu
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page: 7458
    End Page: 7458
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1038/srep07458
    Best OA location URL: https://www.nature.com/articles/srep07458.pdf
    Citation Count: 141
  • Neurobiology of microglial action in CNS injuries: Receptor-mediated signaling mechanisms and functional roles
    2014
    Summary Details
    RESTRICTED
    Title: Neurobiology of microglial action in CNS injuries: Receptor-mediated signaling mechanisms and functional roles
    Author(s): A. Bodek, T. Ferbel, A. C. Melissinos, S. L. Olsen, P. Slattery, P. Tipton, Arindam Das, C. R. Hägen, S. G. Rajeev, С. Окубо
    Journal Name: Progress in Neurobiology
    Publisher: Elsevier BV
    Vol: 119-120
    Issue #:
    Start Page: 60
    End Page: 84
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.pneurobio.2014.06.002
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4121732
    Citation Count: 0
  • Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    2010
    Summary Details
    OPEN
    Title: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    Author(s): Moussa B. H. Youdim
    Journal Name: Rambam Maimonides Medical Journal
    Publisher: Rambam Health Corporation
    Vol: 1
    Issue #: 2
    Start Page: e0011
    End Page: e0011
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.5041/rmmj.10011
    Best OA location URL: https://doi.org/10.5041/rmmj.10011
    Citation Count: 8
  • Endosomal sorting pathways in the pathogenesis of Parkinson's disease
    2020
    Summary Details
    RESTRICTED
    Title: Endosomal sorting pathways in the pathogenesis of Parkinson's disease
    Author(s): Florence Jany‐Catrice
    Journal Name: Progress in Brain Research
    Publisher: Elsevier
    Vol:
    Issue #:
    Start Page: 69
    End Page: 87
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/bs.pbr.2020.02.001
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7206894
    Citation Count: 0
  • Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
    2014
    Summary Details
    OPEN
    Title: Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
    Author(s): John F. Kellie, Richard E. Higgs, John Ryder, Anthony Major, Thomas G. Beach, Charles H. Adler, Kalpana Merchant, Michael D. Knierman
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page: 5797
    End Page: 5797
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1038/srep05797
    Best OA location URL: https://www.nature.com/articles/srep05797.pdf
    Citation Count: 176
  • Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
    2010
    Summary Details
    OPEN
    Title: Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
    Author(s): Erik Kvam, Michael R. Sierks, Charles B. Shoemaker, Anne Messer
    Journal Name: Protein Engineering, Design and Selection
    Publisher: Oxford University Press (OUP)
    Vol: 23
    Issue #: 6
    Start Page: 489
    End Page: 498
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/protein/gzq022
    Best OA location URL: https://academic.oup.com/peds/article-pdf/23/6/489/17494272/gzq022.pdf
    Citation Count: 63
  • Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing
    2013
    Summary Details
    OPEN
    Title: Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing
    Author(s): Kasandra Burgos, Ashkan Javaherian, Roberto Bomprezzi, Layla Ghaffari, Susan N. Rhodes, Amanda Courtright, Waibhav Tembe, Seungchan Kim, Raghu Metpally, Kendall Van Keuren‐Jensen
    Journal Name: RNA
    Publisher: Cold Spring Harbor Laboratory
    Vol: 19
    Issue #: 5
    Start Page: 712
    End Page: 722
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1261/rna.036863.112
    Best OA location URL: http://rnajournal.cshlp.org/content/19/5/712.full.pdf
    Citation Count: 189
  • Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
    2016
    Summary Details
    OPEN
    Title: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
    Author(s): Mariet Allen, Minerva M. Carrasquillo, Cory C. Funk, Ben Heavner, Fanggeng Zou, Curtis Younkin, Jeremy D. Burgess, High-Seng Chai, Julia E. Crook, James A. Eddy, Hong‐Dong Li, Ben Logsdon, Mette A. Peters, Kristen K. Dang, Xue Wang, Daniel Serie, Chen Wang, Thuy Nguyen, Sarah Lincoln, Kimberly G. Malphrus, Gina Bisceglio, Li Ma, Todd E. Golde, Lara M. Mangravite, Yan W. Asmann, Nathan D. Price, Ronald Petersen, Neill R. Graff‐Radford, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner
    Journal Name: Scientific Data
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page: 160089
    End Page: 160089
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/sdata.2016.89
    Best OA location URL: https://www.nature.com/articles/sdata201689.pdf
    Citation Count: 533
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 400
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 190
  • MRI biomarkers — a precision medicine tool in neurology?
    2016
    Summary Details
    RESTRICTED
    Title: MRI biomarkers — a precision medicine tool in neurology?
    Author(s): А В Березин, Н С Келлин, М Б Марков, С В Паротькин
    Journal Name: Nature Reviews Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 6
    Start Page: 323
    End Page: 4
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nrneurol.2016.51
    Citation Count: 0
  • Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    2017
    Summary Details
    OPEN
    Title: Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    Author(s): Malte Gersch, Christina Gladkova, Alexander F. Schubert, Martin A. Michel, Sarah Maslen, David Komander
    Journal Name: Nature Structural & Molecular Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 24
    Issue #: 11
    Start Page: 920
    End Page: 930
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nsmb.3475
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5757785
    Citation Count: 223
  • CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
    2013
    Summary Details
    OPEN
    Title: CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
    Author(s): Brian C. Shonesy, Xiaohan Wang, Kristie L. Rose, Teniel S Ramikie, Victoria S. Cavener, Tyler J. Rentz, Anthony J. Baucum, Nidhi Jalan‐Sakrikar, Ken Mackie, Danny G. Winder, Sachin Patel, Roger Colbran
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 4
    Start Page: 456
    End Page: 463
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3353
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3636998
    Citation Count: 82
  • A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    2018
    Summary Details
    OPEN
    Title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    Author(s): Hongjun Fu, Andrea Possenti, Rosie Freer, Yoshikazu Nakano, Nancy C. Hernandez Villegas, Maoping Tang, Paula Victoria Maglio Cauhy, Benjamin Lassus, Shuo Chen, Stephanie L. Fowler, Helen Y. Figueroa, Edward D. Huey, Gail V.W. Johnson, Michele Vendruscolo, Karen Duff
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 22
    Issue #: 1
    Start Page: 47
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7
    Citation Count: 275
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