7051 - 7075 of 9140 Results
Title
Year
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 122
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OPENTitle: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 27Start Page: 11441End Page: 11446Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0702717104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0702717104Citation Count: 539
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 41Start Page: E3945End Page: 54Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/94836Citation Count: 213
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OPENTitle: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 29Start Page: 10732End Page: 10737Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321785111Best OA location URL: https://www.pnas.org/content/pnas/111/29/10732.full.pdfCitation Count: 343
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OPENTitle: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 11Start Page: 4055End Page: 4060Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1323285111Best OA location URL: https://www.pnas.org/content/pnas/111/11/4055.full.pdfCitation Count: 116
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 224
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP12014OPENTitle: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 18Start Page: 6804End Page: 6809Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321845111Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/104291Citation Count: 215
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OPENTitle: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 28Start Page: 8756End Page: 8761Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1509742112Best OA location URL: https://www.pnas.org/content/pnas/112/28/8756.full.pdfCitation Count: 195
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo2015OPENTitle: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 49Start Page: E6818End Page: 24Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1519430112Best OA location URL: https://www.pnas.org/content/pnas/112/49/E6818.full.pdfCitation Count: 30
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OPENTitle: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 2Start Page: 636End Page: 641Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1220399110Best OA location URL: https://www.pnas.org/content/pnas/110/2/636.full.pdfCitation Count: 210
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation2015OPENTitle: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 15Start Page: E1926End Page: 35Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417883112Best OA location URL: https://www.pnas.org/content/pnas/112/15/E1926.full.pdfCitation Count: 150
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 1Start Page: E34End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 127
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OPENTitle: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 113Issue #: 34Start Page: 9587End Page: 9592Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1610099113Best OA location URL: https://www.pnas.org/content/pnas/113/34/9587.full.pdfCitation Count: 266
- Stochastic electrotransport selectively enhances the transport of highly electromobile molecules2015OPENTitle: Stochastic electrotransport selectively enhances the transport of highly electromobile moleculesJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 46Start Page: E6274End Page: 83Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1510133112Best OA location URL: https://www.pnas.org/content/pnas/112/46/E6274.full.pdfCitation Count: 265
- Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons2016OPENTitle: Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 113Issue #: 47Start Page: E7564End Page: E7571Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1608784113Best OA location URL: https://www.pnas.org/content/pnas/113/47/E7564.full.pdfCitation Count: 60
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OPENTitle: Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 115Issue #: 11Start Page: E2634End Page: E2643Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1713849115Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5856519Citation Count: 231
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OPENTitle: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasisJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 114Issue #: 5Start Page: 1165End Page: 1170Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1522872114Best OA location URL: https://www.pnas.org/content/pnas/114/5/1165.full.pdfCitation Count: 121
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OPENTitle: Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 114Issue #: 10Start Page: 2735End Page: 2740Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1621218114Best OA location URL: https://kclpure.kcl.ac.uk/portal/en/publications/fe4ac1f8-01d0-455f-938a-1a1dbc447b69Citation Count: 40
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OPENTitle: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 115Issue #: 22Start Page: E5164End Page: E5173Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1718946115Best OA location URL: https://www.pnas.org/content/pnas/115/22/E5164.full.pdfCitation Count: 118
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RESTRICTEDTitle: Multi-modal and targeted imaging improves automated mid-brain segmentationJournal Name: SPIE ProceedingsPublisher: SPIEVol: 10133Issue #:Start Page: 101330JEnd Page: 101330JPublication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1117/12.2254428Best OA location URL: http://doi.org/10.1117/12.2254428Citation Count: 4
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RESTRICTEDTitle: Multi-scale hippocampal parcellation improves atlas-based segmentation accuracyJournal Name: SPIE ProceedingsPublisher: SPIEVol: 10133Issue #:Start Page: 101332DEnd Page: 101332DPublication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1117/12.2254425Best OA location URL: http://doi.org/10.1117/12.2254425Citation Count: 17
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OPENTitle: µ Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's DiseaseJournal Name: The Journal of NeurosciencePublisher: Society for NeuroscienceVol: 40Issue #: 35Start Page: 6812End Page: 6819Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1523/jneurosci.0610-20.2020Best OA location URL: https://www.jneurosci.org/content/jneuro/40/35/6812.full.pdfCitation Count: 29
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OPENTitle: Questioning the Meaning of a Change on the Alzheimer’s Disease Assessment Scale–Cognitive Subscale (ADAS-Cog): Noncomparable Scores and Item-Specific Effects Over TimeJournal Name: AssessmentPublisher: SAGE PublicationsVol: 28Issue #: 6Start Page: 1708End Page: 1722Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1177/1073191120915273Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/1073191120915273Citation Count: 10
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OPENTitle: A 12-month, dose-level blinded safety and efficacy study of levodopa inhalation powder (CVT-301, Inbrija) in patients with Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 81Issue #:Start Page: 144End Page: 150Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.parkreldis.2020.10.029Best OA location URL: http://www.prd-journal.com/article/S1353802020308221/pdfCitation Count: 25
- Midbrain hyperechogenicity, hyposmia, mild parkinsonian signs and risk for incident Parkinson's disease over 10 years: A prospective population-based study2019RESTRICTEDTitle: Midbrain hyperechogenicity, hyposmia, mild parkinsonian signs and risk for incident Parkinson's disease over 10 years: A prospective population-based studyJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 70Issue #:Start Page: 51End Page: 54Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.12.008Citation Count: 39