7401 - 7425 of 9039 Results
Title
Year
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OPENTitle: GSK2578215A; A potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 17Start Page: 5625End Page: 5629Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.06.104Best OA location URL: http://hdl.handle.net/10871/35665Citation Count: 151
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OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 88
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OPENTitle: Large-scale replication and heterogeneity in Parkinson disease genetic lociJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 79Issue #: 7Start Page: 659End Page: 667Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e318264e353Best OA location URL: https://n.neurology.org/content/neurology/79/7/659.full.pdfCitation Count: 132
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions2010OPENTitle: Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusionsJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 42Issue #: 3Start Page: 234End Page: 239Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ng.536Best OA location URL: http://doi.org/10.1038/ng.536Citation Count: 612
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OPENTitle: Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar DegenerationJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 68Issue #: 4Start Page: 488End Page: 488Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2011.53Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3160280Citation Count: 121
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OPENTitle: Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsyJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 35Issue #: 6Start Page: 1514.e1End Page: 1514.e12Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2014.01.010Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2014.01.010Citation Count: 50
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OPENTitle: Genetic variability at the PARK16 locusJournal Name: European Journal of Human GeneticsPublisher: Springer Science and Business Media LLCVol: 18Issue #: 12Start Page: 1356End Page: 1359Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ejhg.2010.125Best OA location URL: https://www.nature.com/articles/ejhg2010125.pdfCitation Count: 94
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OPENTitle: Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locusJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 2Issue #: 1Start Page: 440End Page: 440Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-sa, cc-by-nc-saDOI - Digital Object Identifier: 10.1038/ncomms1453Best OA location URL: https://www.nature.com/articles/ncomms1453.pdfCitation Count: 497
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OPENTitle: Widespread sex differences in gene expression and splicing in the adult human brainJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page: 2771End Page: 2771Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/ncomms3771Best OA location URL: https://kclpure.kcl.ac.uk/portal/en/publications/75c8359f-d7e0-4c9d-8d86-c004995b7417Citation Count: 338
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OPENTitle: Genetic variability in the regulation of gene expression in ten regions of the human brainJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 17Issue #: 10Start Page: 1418End Page: 1428Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nn.3801Best OA location URL: http://doi.org/10.1038/nn.3801Citation Count: 711
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OPENTitle: Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodiesJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 453Issue #: 1Start Page: 101End Page: 113Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1042/bj20121742Best OA location URL: https://portlandpress.com/biochemj/article-pdf/453/1/101/675176/bj4530101.pdfCitation Count: 95
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OPENTitle: Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicityJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 22Issue #: 2Start Page: 328End Page: 344Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds431Best OA location URL: https://academic.oup.com/hmg/article-pdf/22/2/328/1857445/dds431.pdfCitation Count: 75
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OPENTitle: Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegenerationJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 23Issue #: 17Start Page: 4621End Page: 4638Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddu178Best OA location URL: https://academic.oup.com/hmg/article-pdf/23/17/4621/2215861/ddu178.pdfCitation Count: 174
- Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research2012OPENTitle: Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease ResearchJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 8Start Page: e43099End Page: e43099Publication Date:Open Access(OA) Status: OPENLicense: cc0, cc0DOI - Digital Object Identifier: 10.1371/journal.pone.0043099Best OA location URL: https://escholarship.org/uc/item/0hr9m7btCitation Count: 141
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OPENTitle: Role of Elongation and Secondary Pathways in S6 Amyloid Fibril GrowthJournal Name: Biophysical JournalPublisher: Elsevier BVVol: 102Issue #: 9Start Page: 2167End Page: 2175Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bpj.2012.03.047Best OA location URL: http://www.cell.com/article/S0006349512003888/pdfCitation Count: 35
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OPENTitle: Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brainJournal Name: Journal of NeurochemistryPublisher: WileyVol: 135Issue #: 6Start Page: 1242End Page: 1256Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1111/jnc.13369Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.13369Citation Count: 71
- Olfaction inParkinsingle and compound heterozygotes in a cohort of young onset Parkinson's disease patients2015RESTRICTEDTitle: Olfaction inParkinsingle and compound heterozygotes in a cohort of young onset Parkinson's disease patientsJournal Name: Acta Neurologica ScandinavicaPublisher: WileyVol: 134Issue #: 4Start Page: 271End Page: 276Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/ane.12538Citation Count: 24
- The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid Formation2014RESTRICTEDTitle: The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid FormationJournal Name: Journal of the American Chemical SocietyPublisher: American Chemical Society (ACS)Vol: 136Issue #: 10Start Page: 3859End Page: 3868Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/ja411577tCitation Count: 257
- Is the MC1R variant p.R160W associated with Parkinson's?2015RESTRICTEDTitle: Is the MC1R variant p.R160W associated with Parkinson's?Journal Name: Annals of NeurologyPublisher: WileyVol: 79Issue #: 1Start Page: 159End Page: 161Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/ana.24527Citation Count: 19
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OPENTitle: Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvationJournal Name: Biochemical and Biophysical Research CommunicationsPublisher: Elsevier BVVol: 441Issue #: 4Start Page: 862End Page: 866Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.bbrc.2013.10.159Best OA location URL: https://doi.org/10.1016/j.bbrc.2013.10.159Citation Count: 86
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OPENTitle: Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple SclerosisJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 80Issue #: 1Start Page: 62End Page: 72Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.biopsych.2015.11.022Best OA location URL: https://kclpure.kcl.ac.uk/ws/files/46558917/1_s2.0_S0006322315010252_main.pdfCitation Count: 148
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OPENTitle: SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 9Start Page: 1333End Page: 1344Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27770Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7322732Citation Count: 28
- Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases2016OPENTitle: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPasesJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.12813Best OA location URL: https://doi.org/10.7554/elife.12813Citation Count: 1079
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OPENTitle: Exercise response in Parkinson’s disease: insights from a cross-sectional comparison with sedentary controls and a per-protocol analysis of a randomised controlled trialJournal Name: BMJ OpenPublisher: BMJVol: 7Issue #: 12Start Page: e017194End Page: e017194Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1136/bmjopen-2017-017194Best OA location URL: https://bmjopen.bmj.com/content/bmjopen/7/12/e017194.full.pdfCitation Count: 38
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OPENTitle: Disease-related patterns of in vivo pathology in Corticobasal syndromeJournal Name: European Journal of Nuclear Medicine and Molecular ImagingPublisher: Springer Science and Business Media LLCVol: 45Issue #: 13Start Page: 2413End Page: 2425Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1007/s00259-018-4104-2Best OA location URL: https://kclpure.kcl.ac.uk/portal/en/publications/9fe6a2c3-b627-4290-99fe-c31eb72bafcbCitation Count: 31