7826 - 7850 of 7939 Results
Title
Year
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulatorsJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 18Issue #: 20Start Page: 5626End Page: 5630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.08.087Best OA location URL: https://europepmc.org/articles/pmc3182458?pdf=renderCitation Count: 55
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OPENTitle: Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson diseaseJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 118Issue #: 9Start Page: 3087End Page: 3097Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci35781Best OA location URL: http://www.jci.org/articles/view/35781/files/pdfCitation Count: 186
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OPENTitle: Enantiomeric Propanolamines as selectiveN-Methyl-d-aspartate 2B Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 51Issue #: 18Start Page: 5506End Page: 5521Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm8002153Best OA location URL: https://europepmc.org/articles/pmc3142473?pdf=renderCitation Count: 25
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OPENTitle: Generation of Stable Transgenic C. elegans Using MicroinjectionJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 18Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/833Best OA location URL: https://europepmc.org/articles/pmc3253564?pdf=renderCitation Count: 81
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OPENTitle: A Genome‐wide Scan in an Amish Pedigree with ParkinsonismJournal Name: Annals of Human GeneticsPublisher: WileyVol: 72Issue #: 5Start Page: 621End Page: 629Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1469-1809.2008.00452.xBest OA location URL: https://europepmc.org/articles/pmc2764120?pdf=renderCitation Count: 12
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OPENTitle: GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 105Issue #: 31Start Page: 10907End Page: 10912Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0802437105Best OA location URL: https://www.pnas.org/content/pnas/105/31/10907.full.pdfCitation Count: 245
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OPENTitle: UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicalsJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 454Issue #: 7206Start Page: 846End Page: 851Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nature07181Best OA location URL: https://europepmc.org/articles/pmc4101536?pdf=renderCitation Count: 671
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OPENTitle: Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4Journal Name: Molecular PharmacologyPublisher: Elsevier BVVol: 74Issue #: 5Start Page: 1345End Page: 1358Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1124/mol.108.049551Best OA location URL: https://europepmc.org/articles/pmc2574552?pdf=renderCitation Count: 180
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OPENTitle: Neuronal gene expression correlates of Parkinson's disease with dementiaJournal Name: Movement DisordersPublisher: WileyVol: 23Issue #: 11Start Page: 1588End Page: 1595Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22184Best OA location URL: https://europepmc.org/articles/pmc2666445?pdf=renderCitation Count: 47
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OPENTitle: Activation of recombinant NR1/NR2C NMDA receptorsJournal Name: The Journal of PhysiologyPublisher: WileyVol: 586Issue #: 18Start Page: 4425End Page: 4439Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1113/jphysiol.2008.158634Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1113/jphysiol.2008.158634Citation Count: 105
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OPENTitle: Application of a C. elegans Dopamine Neuron Degeneration Assay for the Validation of Potential Parkinson's Disease GenesJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 17Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/835Best OA location URL: https://europepmc.org/articles/pmc3253614?pdf=renderCitation Count: 43
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OPENTitle: Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian ratsJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 16Issue #: 9Start Page: 1572End Page: 1579Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2008.146Best OA location URL: http://www.cell.com/article/S1525001616320548/pdfCitation Count: 110
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OPENTitle: Evaluation of α-synuclein immunohistochemical methods used by invited expertsJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 116Issue #: 3Start Page: 277End Page: 288Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-008-0409-8Best OA location URL: https://europepmc.org/articles/pmc2708176?pdf=renderCitation Count: 165
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OPENTitle: The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviorsJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 32Issue #: 2Start Page: 229End Page: 242Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2008.06.018Best OA location URL: https://europepmc.org/articles/pmc2886670?pdf=renderCitation Count: 62
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OPENTitle: Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control studyJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 7Issue #: 7Start Page: 583End Page: 590Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/s1474-4422(08)70117-0Best OA location URL: http://www.thelancet.com/article/S1474442208701170/pdfCitation Count: 1375
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RESTRICTEDTitle: Strengths and limitations of genetic mouse models of Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 14Issue #:Start Page: S84End Page: S87Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2008.04.004Best OA location URL: https://europepmc.org/articles/pmc2577895?pdf=renderCitation Count: 74
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RESTRICTEDTitle: Value of genetic models in understanding the cause and mechanisms of Parkinson’s diseaseJournal Name: Current Neurology and Neuroscience ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 4Start Page: 288End Page: 296Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s11910-008-0045-7Best OA location URL: https://europepmc.org/articles/pmc4431569?pdf=renderCitation Count: 42
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OPENTitle: Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosisJournal Name: Annals of NeurologyPublisher: WileyVol: 64Issue #: 1Start Page: 60End Page: 70Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.21425Best OA location URL: https://europepmc.org/articles/pmc2674108?pdf=renderCitation Count: 670
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OPENTitle: Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP BiosensorJournal Name: Molecular PharmacologyPublisher: Elsevier BVVol: 74Issue #: 3Start Page: 585End Page: 594Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1124/mol.108.048884Best OA location URL: https://europepmc.org/articles/pmc3766527?pdf=renderCitation Count: 142
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OPENTitle: Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 131Issue #: 7Start Page: 1880End Page: 1894Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awn101Best OA location URL: https://academic.oup.com/brain/article-pdf/131/7/1880/1093630/awn101.pdfCitation Count: 316
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OPENTitle: Changes in attack behavior and activity in EphA5 knockout miceJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1205Issue #:Start Page: 91End Page: 99Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.brainres.2008.02.047Best OA location URL: https://europepmc.org/articles/pmc4042433?pdf=renderCitation Count: 22
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OPENTitle: Therapeutic cloning in individual parkinsonian miceJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 14Issue #: 4Start Page: 379End Page: 381Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nm1732Best OA location URL: https://europepmc.org/articles/pmc2786166?pdf=renderCitation Count: 116
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RESTRICTEDTitle: Protein Aggregation in the Brain: The Molecular Basis for Alzheimer’s and Parkinson’s DiseasesJournal Name: Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 14Issue #: 7-8Start Page: 451End Page: 464Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.2119/2007-00100.irvineBest OA location URL: https://molmed.biomedcentral.com/counter/pdf/10.2119/2007-00100.IrvineCitation Count: 469
- The Sun Health Research Institute Brain Donation Program: Description and Eexperience, 1987–20072008OPENTitle: The Sun Health Research Institute Brain Donation Program: Description and Eexperience, 1987–2007Journal Name: Cell and Tissue BankingPublisher: Springer Science and Business Media LLCVol: 9Issue #: 3Start Page: 229End Page: 245Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1007/s10561-008-9067-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s10561-008-9067-2.pdfCitation Count: 240
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OPENTitle: CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson DiseasesJournal Name: American Journal of Clinical PathologyPublisher: Oxford University Press (OUP)Vol: 129Issue #: 4Start Page: 526End Page: 529Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1309/w01y0b808emeh12lBest OA location URL: https://academic.oup.com/ajcp/article-pdf/129/4/526/24985935/ajcpath129-0526.pdfCitation Count: 254